ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-05

AUTHORS

S P Bell, B Stillman

ABSTRACT

A multiprotein complex that specifically recognizes cellular origins of DNA replication has been identified and purified from the yeast Saccharomyces cerevisiae. We observe a strong correlation between origin function and origin recognition by this activity. Interestingly, specific DNA binding by the origin recognition complex is dependent upon the addition of ATP. We propose that the origin recognition complex acts as the initiator protein for S. cerevisiae origins of DNA replication. More... »

PAGES

128-134

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/357128a0

DOI

http://dx.doi.org/10.1038/357128a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008093514

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1579162


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