Viral envelope fails to deliver? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1998-02

AUTHORS

Dani P. Bolognesi, Thomas J. Matthews

ABSTRACT

Clinical trials of vaccines against the human immunodeficiency virus are underway, but initial results do not seem promising — at least for one type of vaccine. By injecting patients with a recombinant form of a viral envelope protein, gp120, the idea was to induce an antibody response that could fight subsequent infection with the virus. But in a trial of 18 people, all became infected with HIV-1 and, at the level of the immune system, those who had received the vaccine did not seem to deal with the infection any differently than unvaccinated patients. More... »

PAGES

638-639

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/35504

DOI

http://dx.doi.org/10.1038/35504

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045715446

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/9490406


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