The microenvironment of the tumour–host interface View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-05

AUTHORS

L A Liotta, E C Kohn

ABSTRACT

Throughout the entire process of cancer aetiology, progression and metastasis, the microenvironment of the local host tissue can be an active participant. Invasion occurs within a tumour-host microecology, where stroma and tumour cells exchange enzymes and cytokines that modify the local extracellular matrix, stimulate migration, and promote proliferation and survival. A new class of cancer therapies that targets this pathological communication interface between tumour cells and host cells is currently under development. More... »

PAGES

375-379

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/35077241

    DOI

    http://dx.doi.org/10.1038/35077241

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1037985715

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11357145


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