Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-03

AUTHORS

Fadel A. Samatey, Katsumi Imada, Shigehiro Nagashima, Ferenc Vonderviszt, Takashi Kumasaka, Masaki Yamamoto, Keiichi Namba

ABSTRACT

The bacterial flagellar filament is a helical propeller constructed from 11 protofilaments of a single protein, flagellin. The filament switches between left- and right-handed supercoiled forms when bacteria switch their swimming mode between running and tumbling. Supercoiling is produced by two different packing interactions of flagellin called L and R. In switching from L to R, the intersubunit distance ( approximately 52 A) along the protofilament decreases by 0.8 A. Changes in the number of L and R protofilaments govern supercoiling of the filament. Here we report the 2.0 A resolution crystal structure of a Salmonella flagellin fragment of relative molecular mass 41,300. The crystal contains pairs of antiparallel straight protofilaments with the R-type repeat. By simulated extension of the protofilament model, we have identified possible switch regions responsible for the bi-stable mechanical switch that generates the 0.8 A difference in repeat distance. More... »

PAGES

331

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/35066504

DOI

http://dx.doi.org/10.1038/35066504

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020882969

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11268201


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Crystallography, X-Ray", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Flagellin", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Motor Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Peptide Fragments", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Transport", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Salmonella typhimurium", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Japan Science and Technology Agency", 
          "id": "https://www.grid.ac/institutes/grid.419082.6", 
          "name": [
            "*Protonic NanoMachine Project, ERATO, JST, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Samatey", 
        "givenName": "Fadel A.", 
        "id": "sg:person.0676217526.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676217526.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japan Science and Technology Agency", 
          "id": "https://www.grid.ac/institutes/grid.419082.6", 
          "name": [
            "*Protonic NanoMachine Project, ERATO, JST, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Imada", 
        "givenName": "Katsumi", 
        "id": "sg:person.0707206125.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707206125.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Japan Science and Technology Agency", 
          "id": "https://www.grid.ac/institutes/grid.419082.6", 
          "name": [
            "*Protonic NanoMachine Project, ERATO, JST, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Nagashima", 
        "givenName": "Shigehiro", 
        "id": "sg:person.01110502020.68", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110502020.68"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Pannonia", 
          "id": "https://www.grid.ac/institutes/grid.7336.1", 
          "name": [
            "\u2020Department of Physics, University of Veszpr\u00e9m, Egyetem, u.10 H-8201, Hungary"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vonderviszt", 
        "givenName": "Ferenc", 
        "id": "sg:person.0672073303.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672073303.17"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "\u2021RIKEN Harima Institute, 1-1-1 Kouto, Mikazuki, Hyogo 679-5198, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kumasaka", 
        "givenName": "Takashi", 
        "id": "sg:person.01011002721.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011002721.10"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "\u2021RIKEN Harima Institute, 1-1-1 Kouto, Mikazuki, Hyogo 679-5198, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Yamamoto", 
        "givenName": "Masaki", 
        "id": "sg:person.012771421304.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012771421304.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Panasonic (Japan)", 
          "id": "https://www.grid.ac/institutes/grid.410834.a", 
          "name": [
            "*Protonic NanoMachine Project, ERATO, JST, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan", 
            "\u00a7Advanced Technology Research Laboratories, Matsushita Electric Industrial Co., Ltd, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Namba", 
        "givenName": "Keiichi", 
        "id": "sg:person.01331553347.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331553347.38"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0968-0004(00)89080-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000822935"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(78)90285-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002389330"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(97)76066-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004907170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0969-2126(99)80113-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006065225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(77)80153-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006661237"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jsbi.2000.4312", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006768304"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/245380a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006993053", 
          "https://doi.org/10.1038/245380a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/245380a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006993053", 
          "https://doi.org/10.1038/245380a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.114.5.977", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007322401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444999000839", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008525008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1998.2184", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008905836"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0909049597014738", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009976977"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(90)90149-g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012887250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/249073a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013527060", 
          "https://doi.org/10.1038/249073a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(79)90199-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014133511"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0108767390010224", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014210169"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0021889891004399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014885043"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/342648a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015633149", 
          "https://doi.org/10.1038/342648a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/255121a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016034428", 
          "https://doi.org/10.1038/255121a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/34465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016383987", 
          "https://doi.org/10.1038/34465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/34465", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016383987", 
          "https://doi.org/10.1038/34465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.93.26.15108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017351963"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.182.10.2793-2801.2000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019088959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/26.1.323", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021724724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1995.0572", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022150484"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(76)80133-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022366558"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(72)90168-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023114847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1995.0281", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025357908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444994003112", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025573949"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsb0298-125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027385836", 
          "https://doi.org/10.1038/nsb0298-125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1999.3175", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027884535"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(82)90142-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027920259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-5193(76)90016-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031609763"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(91)90946-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031761351"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35000233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034898832", 
          "https://doi.org/10.1038/35000233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35000233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034898832", 
          "https://doi.org/10.1038/35000233"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1997.1111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035142831"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(76)90306-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040667715"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0076-6879(97)77028-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041442837"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(91)90187-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043617799"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/225121a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050450716", 
          "https://doi.org/10.1038/225121a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/249074a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051894411", 
          "https://doi.org/10.1038/249074a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1995.0282", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051967597"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/286628a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053321095", 
          "https://doi.org/10.1038/286628a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/346677a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053585241", 
          "https://doi.org/10.1038/346677a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.235.4787.458", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062533650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.290.5499.2148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062572480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.177.4.1090-1093.1995", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062724512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080707752", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2001-03", 
    "datePublishedReg": "2001-03-01", 
    "description": "The bacterial flagellar filament is a helical propeller constructed from 11 protofilaments of a single protein, flagellin. The filament switches between left- and right-handed supercoiled forms when bacteria switch their swimming mode between running and tumbling. Supercoiling is produced by two different packing interactions of flagellin called L and R. In switching from L to R, the intersubunit distance ( approximately 52 A) along the protofilament decreases by 0.8 A. Changes in the number of L and R protofilaments govern supercoiling of the filament. Here we report the 2.0 A resolution crystal structure of a Salmonella flagellin fragment of relative molecular mass 41,300. The crystal contains pairs of antiparallel straight protofilaments with the R-type repeat. By simulated extension of the protofilament model, we have identified possible switch regions responsible for the bi-stable mechanical switch that generates the 0.8 A difference in repeat distance.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/35066504", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6826", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "410"
      }
    ], 
    "name": "Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling", 
    "pagination": "331", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "637fd3800fa43a6239271c3c47ef351cc04a4950d2f82b310e8c80a11d4ea869"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11268201"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/35066504"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1020882969"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/35066504", 
      "https://app.dimensions.ai/details/publication/pub.1020882969"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:16", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000361_0000000361/records_54017_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://www.nature.com/articles/35066504"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/35066504'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/35066504'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/35066504'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/35066504'


 

This table displays all metadata directly associated to this object as RDF triples.

306 TRIPLES      21 PREDICATES      84 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/35066504 schema:about N0477cfa21f064b39943840fac75b64c8
2 N2a06cf977a3648309181d267b70e95f6
3 N3649a3bfa3ce42d3b50bb60ff65b5f0b
4 N3d5638daf4de4735bd58a9089828a02f
5 N518b2f82680a4e3788648921dc8896d0
6 N560a551a3d60477abed6ce71e9930aa5
7 N5b2e6ed043dd4fc6ae6db073db5d2dad
8 Ndb268644a6114ef295d124f2ab956cd0
9 Nf644b13d0a1c4ebbba32763b26204c82
10 anzsrc-for:06
11 anzsrc-for:0601
12 schema:author N14d102452e7d4d4e8ccc650f9cdf3cbf
13 schema:citation sg:pub.10.1038/225121a0
14 sg:pub.10.1038/245380a0
15 sg:pub.10.1038/249073a0
16 sg:pub.10.1038/249074a0
17 sg:pub.10.1038/255121a0
18 sg:pub.10.1038/286628a0
19 sg:pub.10.1038/342648a0
20 sg:pub.10.1038/34465
21 sg:pub.10.1038/346677a0
22 sg:pub.10.1038/35000233
23 sg:pub.10.1038/nsb0298-125
24 https://app.dimensions.ai/details/publication/pub.1080707752
25 https://doi.org/10.1006/jmbi.1995.0281
26 https://doi.org/10.1006/jmbi.1995.0282
27 https://doi.org/10.1006/jmbi.1995.0572
28 https://doi.org/10.1006/jmbi.1997.1111
29 https://doi.org/10.1006/jmbi.1998.2184
30 https://doi.org/10.1006/jmbi.1999.3175
31 https://doi.org/10.1006/jsbi.2000.4312
32 https://doi.org/10.1016/0022-2836(72)90168-4
33 https://doi.org/10.1016/0022-2836(76)90306-5
34 https://doi.org/10.1016/0022-2836(78)90285-1
35 https://doi.org/10.1016/0022-2836(79)90199-2
36 https://doi.org/10.1016/0022-2836(82)90142-5
37 https://doi.org/10.1016/0022-2836(90)90149-g
38 https://doi.org/10.1016/0022-2836(91)90187-b
39 https://doi.org/10.1016/0022-2836(91)90946-4
40 https://doi.org/10.1016/0022-5193(76)90016-3
41 https://doi.org/10.1016/s0022-2836(76)80133-7
42 https://doi.org/10.1016/s0022-2836(77)80153-8
43 https://doi.org/10.1016/s0076-6879(97)76066-x
44 https://doi.org/10.1016/s0076-6879(97)77028-9
45 https://doi.org/10.1016/s0968-0004(00)89080-5
46 https://doi.org/10.1016/s0969-2126(99)80113-0
47 https://doi.org/10.1073/pnas.93.26.15108
48 https://doi.org/10.1083/jcb.114.5.977
49 https://doi.org/10.1093/nar/26.1.323
50 https://doi.org/10.1107/s0021889891004399
51 https://doi.org/10.1107/s0108767390010224
52 https://doi.org/10.1107/s0907444994003112
53 https://doi.org/10.1107/s0907444999000839
54 https://doi.org/10.1107/s0909049597014738
55 https://doi.org/10.1126/science.235.4787.458
56 https://doi.org/10.1126/science.290.5499.2148
57 https://doi.org/10.1128/jb.177.4.1090-1093.1995
58 https://doi.org/10.1128/jb.182.10.2793-2801.2000
59 schema:datePublished 2001-03
60 schema:datePublishedReg 2001-03-01
61 schema:description The bacterial flagellar filament is a helical propeller constructed from 11 protofilaments of a single protein, flagellin. The filament switches between left- and right-handed supercoiled forms when bacteria switch their swimming mode between running and tumbling. Supercoiling is produced by two different packing interactions of flagellin called L and R. In switching from L to R, the intersubunit distance ( approximately 52 A) along the protofilament decreases by 0.8 A. Changes in the number of L and R protofilaments govern supercoiling of the filament. Here we report the 2.0 A resolution crystal structure of a Salmonella flagellin fragment of relative molecular mass 41,300. The crystal contains pairs of antiparallel straight protofilaments with the R-type repeat. By simulated extension of the protofilament model, we have identified possible switch regions responsible for the bi-stable mechanical switch that generates the 0.8 A difference in repeat distance.
62 schema:genre research_article
63 schema:inLanguage en
64 schema:isAccessibleForFree false
65 schema:isPartOf N92e8e1beb8de4eb3bbde5b4de2f57675
66 Nb76b9f03521b4c5e943477e623f1f2ec
67 sg:journal.1018957
68 schema:name Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling
69 schema:pagination 331
70 schema:productId N75bc2eb60f7d4076b2585cd5d06ab90b
71 N7bf01941f2ea436390f44c82ad0c2df5
72 N91635684b26b4c5f94842decd2dbbb28
73 Nb30665eefa404663907c4ad934f1c34e
74 Nb3a732a2e77549998d867ba2b0d28985
75 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020882969
76 https://doi.org/10.1038/35066504
77 schema:sdDatePublished 2019-04-11T12:16
78 schema:sdLicense https://scigraph.springernature.com/explorer/license/
79 schema:sdPublisher Nb8454c1e8e474263ba8766a3f112e778
80 schema:url https://www.nature.com/articles/35066504
81 sgo:license sg:explorer/license/
82 sgo:sdDataset articles
83 rdf:type schema:ScholarlyArticle
84 N01ce7b3bba2049c9a36522a0672e1c91 rdf:first sg:person.0707206125.15
85 rdf:rest Nd0839f04d8724c0a80516eb81b389acc
86 N0477cfa21f064b39943840fac75b64c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Models, Molecular
88 rdf:type schema:DefinedTerm
89 N10aab6e118814898813b92ab12bd09c2 schema:name ‡RIKEN Harima Institute, 1-1-1 Kouto, Mikazuki, Hyogo 679-5198, Japan
90 rdf:type schema:Organization
91 N14d102452e7d4d4e8ccc650f9cdf3cbf rdf:first sg:person.0676217526.54
92 rdf:rest N01ce7b3bba2049c9a36522a0672e1c91
93 N2a06cf977a3648309181d267b70e95f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Protein Conformation
95 rdf:type schema:DefinedTerm
96 N3649a3bfa3ce42d3b50bb60ff65b5f0b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Flagellin
98 rdf:type schema:DefinedTerm
99 N36c6bfa4e665451e975748021ddfe047 rdf:first sg:person.01331553347.38
100 rdf:rest rdf:nil
101 N3d5638daf4de4735bd58a9089828a02f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
102 schema:name Salmonella typhimurium
103 rdf:type schema:DefinedTerm
104 N508ebb3c4aca4d668d34cfb95fd84c57 rdf:first sg:person.0672073303.17
105 rdf:rest Na92fd85ac4fc4282a44c26f2f8ef0d58
106 N518b2f82680a4e3788648921dc8896d0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
107 schema:name Crystallography, X-Ray
108 rdf:type schema:DefinedTerm
109 N560a551a3d60477abed6ce71e9930aa5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
110 schema:name Molecular Motor Proteins
111 rdf:type schema:DefinedTerm
112 N5b2e6ed043dd4fc6ae6db073db5d2dad schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
113 schema:name Peptide Fragments
114 rdf:type schema:DefinedTerm
115 N75bc2eb60f7d4076b2585cd5d06ab90b schema:name dimensions_id
116 schema:value pub.1020882969
117 rdf:type schema:PropertyValue
118 N7bf01941f2ea436390f44c82ad0c2df5 schema:name doi
119 schema:value 10.1038/35066504
120 rdf:type schema:PropertyValue
121 N91635684b26b4c5f94842decd2dbbb28 schema:name pubmed_id
122 schema:value 11268201
123 rdf:type schema:PropertyValue
124 N92e8e1beb8de4eb3bbde5b4de2f57675 schema:volumeNumber 410
125 rdf:type schema:PublicationVolume
126 Na92fd85ac4fc4282a44c26f2f8ef0d58 rdf:first sg:person.01011002721.10
127 rdf:rest Ncb10154c0abd4b3a8009634f66c6f408
128 Nb30665eefa404663907c4ad934f1c34e schema:name readcube_id
129 schema:value 637fd3800fa43a6239271c3c47ef351cc04a4950d2f82b310e8c80a11d4ea869
130 rdf:type schema:PropertyValue
131 Nb3a732a2e77549998d867ba2b0d28985 schema:name nlm_unique_id
132 schema:value 0410462
133 rdf:type schema:PropertyValue
134 Nb76b9f03521b4c5e943477e623f1f2ec schema:issueNumber 6826
135 rdf:type schema:PublicationIssue
136 Nb8454c1e8e474263ba8766a3f112e778 schema:name Springer Nature - SN SciGraph project
137 rdf:type schema:Organization
138 Ncb10154c0abd4b3a8009634f66c6f408 rdf:first sg:person.012771421304.81
139 rdf:rest N36c6bfa4e665451e975748021ddfe047
140 Nd0839f04d8724c0a80516eb81b389acc rdf:first sg:person.01110502020.68
141 rdf:rest N508ebb3c4aca4d668d34cfb95fd84c57
142 Ndb268644a6114ef295d124f2ab956cd0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Protein Transport
144 rdf:type schema:DefinedTerm
145 Neb13a556a3424cad852c6e712eed3a80 schema:name ‡RIKEN Harima Institute, 1-1-1 Kouto, Mikazuki, Hyogo 679-5198, Japan
146 rdf:type schema:Organization
147 Nf644b13d0a1c4ebbba32763b26204c82 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Mutation
149 rdf:type schema:DefinedTerm
150 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
151 schema:name Biological Sciences
152 rdf:type schema:DefinedTerm
153 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
154 schema:name Biochemistry and Cell Biology
155 rdf:type schema:DefinedTerm
156 sg:journal.1018957 schema:issn 0090-0028
157 1476-4687
158 schema:name Nature
159 rdf:type schema:Periodical
160 sg:person.01011002721.10 schema:affiliation N10aab6e118814898813b92ab12bd09c2
161 schema:familyName Kumasaka
162 schema:givenName Takashi
163 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01011002721.10
164 rdf:type schema:Person
165 sg:person.01110502020.68 schema:affiliation https://www.grid.ac/institutes/grid.419082.6
166 schema:familyName Nagashima
167 schema:givenName Shigehiro
168 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110502020.68
169 rdf:type schema:Person
170 sg:person.012771421304.81 schema:affiliation Neb13a556a3424cad852c6e712eed3a80
171 schema:familyName Yamamoto
172 schema:givenName Masaki
173 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012771421304.81
174 rdf:type schema:Person
175 sg:person.01331553347.38 schema:affiliation https://www.grid.ac/institutes/grid.410834.a
176 schema:familyName Namba
177 schema:givenName Keiichi
178 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331553347.38
179 rdf:type schema:Person
180 sg:person.0672073303.17 schema:affiliation https://www.grid.ac/institutes/grid.7336.1
181 schema:familyName Vonderviszt
182 schema:givenName Ferenc
183 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672073303.17
184 rdf:type schema:Person
185 sg:person.0676217526.54 schema:affiliation https://www.grid.ac/institutes/grid.419082.6
186 schema:familyName Samatey
187 schema:givenName Fadel A.
188 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0676217526.54
189 rdf:type schema:Person
190 sg:person.0707206125.15 schema:affiliation https://www.grid.ac/institutes/grid.419082.6
191 schema:familyName Imada
192 schema:givenName Katsumi
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707206125.15
194 rdf:type schema:Person
195 sg:pub.10.1038/225121a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050450716
196 https://doi.org/10.1038/225121a0
197 rdf:type schema:CreativeWork
198 sg:pub.10.1038/245380a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006993053
199 https://doi.org/10.1038/245380a0
200 rdf:type schema:CreativeWork
201 sg:pub.10.1038/249073a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013527060
202 https://doi.org/10.1038/249073a0
203 rdf:type schema:CreativeWork
204 sg:pub.10.1038/249074a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051894411
205 https://doi.org/10.1038/249074a0
206 rdf:type schema:CreativeWork
207 sg:pub.10.1038/255121a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016034428
208 https://doi.org/10.1038/255121a0
209 rdf:type schema:CreativeWork
210 sg:pub.10.1038/286628a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053321095
211 https://doi.org/10.1038/286628a0
212 rdf:type schema:CreativeWork
213 sg:pub.10.1038/342648a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015633149
214 https://doi.org/10.1038/342648a0
215 rdf:type schema:CreativeWork
216 sg:pub.10.1038/34465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016383987
217 https://doi.org/10.1038/34465
218 rdf:type schema:CreativeWork
219 sg:pub.10.1038/346677a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053585241
220 https://doi.org/10.1038/346677a0
221 rdf:type schema:CreativeWork
222 sg:pub.10.1038/35000233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034898832
223 https://doi.org/10.1038/35000233
224 rdf:type schema:CreativeWork
225 sg:pub.10.1038/nsb0298-125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027385836
226 https://doi.org/10.1038/nsb0298-125
227 rdf:type schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1080707752 schema:CreativeWork
229 https://doi.org/10.1006/jmbi.1995.0281 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025357908
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1006/jmbi.1995.0282 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051967597
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1006/jmbi.1995.0572 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022150484
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1006/jmbi.1997.1111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035142831
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1006/jmbi.1998.2184 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008905836
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1006/jmbi.1999.3175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027884535
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1006/jsbi.2000.4312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006768304
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1016/0022-2836(72)90168-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023114847
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1016/0022-2836(76)90306-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040667715
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1016/0022-2836(78)90285-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002389330
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1016/0022-2836(79)90199-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014133511
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1016/0022-2836(82)90142-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027920259
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1016/0022-2836(90)90149-g schema:sameAs https://app.dimensions.ai/details/publication/pub.1012887250
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1016/0022-2836(91)90187-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1043617799
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1016/0022-2836(91)90946-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031761351
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1016/0022-5193(76)90016-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031609763
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1016/s0022-2836(76)80133-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022366558
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1016/s0022-2836(77)80153-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006661237
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1016/s0076-6879(97)76066-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004907170
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1016/s0076-6879(97)77028-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041442837
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1016/s0968-0004(00)89080-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000822935
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1016/s0969-2126(99)80113-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006065225
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1073/pnas.93.26.15108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017351963
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1083/jcb.114.5.977 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007322401
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1093/nar/26.1.323 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021724724
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1107/s0021889891004399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014885043
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1107/s0108767390010224 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014210169
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1107/s0907444994003112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025573949
284 rdf:type schema:CreativeWork
285 https://doi.org/10.1107/s0907444999000839 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008525008
286 rdf:type schema:CreativeWork
287 https://doi.org/10.1107/s0909049597014738 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009976977
288 rdf:type schema:CreativeWork
289 https://doi.org/10.1126/science.235.4787.458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062533650
290 rdf:type schema:CreativeWork
291 https://doi.org/10.1126/science.290.5499.2148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062572480
292 rdf:type schema:CreativeWork
293 https://doi.org/10.1128/jb.177.4.1090-1093.1995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062724512
294 rdf:type schema:CreativeWork
295 https://doi.org/10.1128/jb.182.10.2793-2801.2000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019088959
296 rdf:type schema:CreativeWork
297 https://www.grid.ac/institutes/grid.410834.a schema:alternateName Panasonic (Japan)
298 schema:name *Protonic NanoMachine Project, ERATO, JST, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan
299 §Advanced Technology Research Laboratories, Matsushita Electric Industrial Co., Ltd, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan
300 rdf:type schema:Organization
301 https://www.grid.ac/institutes/grid.419082.6 schema:alternateName Japan Science and Technology Agency
302 schema:name *Protonic NanoMachine Project, ERATO, JST, 3-4 Hikaridai, Seika, Kyoto 619-0237, Japan
303 rdf:type schema:Organization
304 https://www.grid.ac/institutes/grid.7336.1 schema:alternateName University of Pannonia
305 schema:name †Department of Physics, University of Veszprém, Egyetem, u.10 H-8201, Hungary
306 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...