sg:pub.10.1038/35057062 - Springer Nature SciGraph

Article Info

DATE

2001-02

AUTHORS

E S Lander, L M Linton, B Birren, C Nusbaum, M C Zody, J Baldwin, K Devon, K Dewar, M Doyle, W FitzHugh, R Funke, D Gage, K Harris, A Heaford, J Howland, L Kann, J Lehoczky, R LeVine, P McEwan, K McKernan, J Meldrim, J P Mesirov, C Miranda, W Morris, J Naylor, C Raymond, M Rosetti, R Santos, A Sheridan, C Sougnez, Y Stange-Thomann, N Stojanovic, A Subramanian, D Wyman, J Rogers, J Sulston, R Ainscough, S Beck, D Bentley, J Burton, C Clee, N Carter, A Coulson, R Deadman, P Deloukas, A Dunham, I Dunham, R Durbin, L French, D Grafham, S Gregory, T Hubbard, S Humphray, A Hunt, M Jones, C Lloyd, A McMurray, L Matthews, S Mercer, S Milne, J C Mullikin, A Mungall, R Plumb, M Ross, R Shownkeen, S Sims, R H Waterston, R K Wilson, L W Hillier, J D McPherson, M A Marra, E R Mardis, L A Fulton, A T Chinwalla, K H Pepin, W R Gish, S L Chissoe, M C Wendl, K D Delehaunty, T L Miner, A Delehaunty, J B Kramer, L L Cook, R S Fulton, D L Johnson, P J Minx, S W Clifton, T Hawkins, E Branscomb, P Predki, P Richardson, S Wenning, T Slezak, N Doggett, J F Cheng, A Olsen, S Lucas, C Elkin, E Uberbacher, M Frazier, R A Gibbs, D M Muzny, S E Scherer, J B Bouck, E J Sodergren, K C Worley, C M Rives, J H Gorrell, M L Metzker, S L Naylor, R S Kucherlapati, D L Nelson, G M Weinstock, Y Sakaki, A Fujiyama, M Hattori, T Yada, A Toyoda, T Itoh, C Kawagoe, H Watanabe, Y Totoki, T Taylor, J Weissenbach, R Heilig, W Saurin, F Artiguenave, P Brottier, T Bruls, E Pelletier, C Robert, P Wincker, D R Smith, L Doucette-Stamm, M Rubenfield, K Weinstock, H M Lee, J Dubois, A Rosenthal, M Platzer, G Nyakatura, S Taudien, A Rump, H Yang, J Yu, J Wang, G Huang, J Gu, L Hood, L Rowen, A Madan, S Qin, R W Davis, N A Federspiel, A P Abola, M J Proctor, R M Myers, J Schmutz, M Dickson, J Grimwood, D R Cox, M V Olson, R Kaul, C Raymond, N Shimizu, K Kawasaki, S Minoshima, G A Evans, M Athanasiou, R Schultz, B A Roe, F Chen, H Pan, J Ramser, H Lehrach, R Reinhardt, W R McCombie, M de la Bastide, N Dedhia, H Blöcker, K Hornischer, G Nordsiek, R Agarwala, L Aravind, J A Bailey, A Bateman, S Batzoglou, E Birney, P Bork, D G Brown, C B Burge, L Cerutti, H C Chen, D Church, M Clamp, R R Copley, T Doerks, S R Eddy, E E Eichler, T S Furey, J Galagan, J G Gilbert, C Harmon, Y Hayashizaki, D Haussler, H Hermjakob, K Hokamp, W Jang, L S Johnson, T A Jones, S Kasif, A Kaspryzk, S Kennedy, W J Kent, P Kitts, E V Koonin, I Korf, D Kulp, D Lancet, T M Lowe, A McLysaght, T Mikkelsen, J V Moran, N Mulder, V J Pollara, C P Ponting, G Schuler, J Schultz, G Slater, A F Smit, E Stupka, J Szustakowki, D Thierry-Mieg, J Thierry-Mieg, L Wagner, J Wallis, R Wheeler, A Williams, Y I Wolf, K H Wolfe, S P Yang, R F Yeh, F Collins, M S Guyer, J Peterson, A Felsenfeld, K A Wetterstrand, A Patrinos, M J Morgan, P de Jong, J J Catanese, K Osoegawa, H Shizuya, S Choi, Y J Chen, J Szustakowki

ABSTRACT

The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence. More... »

PAGES

860

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Journal

TITLE

Nature

ISSUE

6822

VOLUME

409

Subjects

FOR: Genetics

FOR: Biological Sciences

MESH: Animals

MESH: Chromosome Mapping

MESH: Conserved Sequence

MESH: Cpg Islands

MESH: Dna Transposable Elements

MESH: Databases, Factual

MESH: Drug Industry

MESH: Evolution, Molecular

MESH: Forecasting

MESH: Gc Rich Sequence

MESH: Gene Duplication

MESH: Genes

MESH: Genetic Diseases, Inborn

MESH: Genetics, Medical

MESH: Genome, Human

MESH: Human Genome Project

MESH: Humans

MESH: Mutation

MESH: Private Sector

MESH: Proteins

MESH: Proteome

MESH: Public Sector

MESH: Rna

MESH: Repetitive Sequences, Nucleic Acid

MESH: Sequence Analysis, Dna

MESH: Species Specificity

Author Affiliations

Massachusetts Institute of Technology

From Grant

The Human Genome Sequencing Center

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Use Of Whole Exome Sequencing/Whole Genome Sequencing In The Plain Communities

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High Throughput Methods Comprising Analysis Of Repetitive Element Dna Methylation

Compositions And Methods For Regulating Cell Osmolarity

Single Molecule Sequencing Of Captured Nucleic Acids

Engineered Protein Kinases Which Can Utilize Modified Nucleotide Triphosphate Substrates

Genetically Modified Mice That Produce Hybrid Antibodies

Histone Acetyltransferase Modulators And Uses Thereof

Method Of Determining The Nucleotide Sequence Of Oligonucleotides And Dna Molecules

Devices And Methods For Target Molecule Characterization

Methods Of Modifying Eukaryotic Cells

Oligonucleotides Useful For Detecting And Analyzing Nucleic Acids Of Interest

Methods Of Producing Hybrid Antibodies

Methods Of Making A Nucleic Acid Encoding A Human Variable Region

Characterizing Stretched Polynucleotides In A Synthetic Nanopassage

Multipurpose Analysis Using Second Harmonic Generating Nanoprobes

Methods Of Producing Hybrid Antibodies

Massively Parallel Continguity Mapping

Reagents, Methods, And Libraries For Bead-Based Sequencing

Methods For Bead-Based Sequencing

Methods Of Modulating Immune Function

Short Cycle Methods For Sequencing Polynucleotides

Identification And Characterization Of Protein Fragments

Noninvasive Diagnosis Of Fetal Aneuploidy By Sequencing

Rapid Aneuploidy Detection

Methods For Non-Invasive Prenatal Ploidy Calling

Multiple Tagging Of Individual Long Dna Fragments

Reagents, Methods, And Libraries For Bead-Based Sequencing

Single Molecule Sequencing Of Captured Nucleic Acids

Methods For Placing, Accepting, And Filling Orders For Products And Services

Protein With Fusogenic Activity, Nucleic Acid Sequences Encoding Said Protein And Pharmaceutical Compositions Comprising The Same

Ange Gene In Atopy

Reagents, Methods, And Libraries For Bead-Based Sequencing

Dna Sequencing With Non-Fluorescent Nucleotide Reversible Terminators And Cleavable Label Modified Nucleotide Terminators

Isolated Stem Cell Comprising A Xic Flanking Region Transgene

Methods And Kits For Treating And Classifying Individuals At Risk Of Or Suffering From Trap1 Change-Of-Function

Detecting And Sorting Methylated Dna Using A Synthetic Nanopore

Short Cycle Methods For Sequencing Polynucleotides

Method Of Determining The Nucleotide Sequence Of Oligonucleotides And Dna Molecules

Rapid Analysis Of Variations In A Genome

Methods And Kits For Analyzing Polynucleotide Sequences

Method Of Determining The Nucleotide Sequence Of Oligonucleotides And Dna Molecules

Non-Invasive Determination Of Fetal Inheritance Of Parental Haplotypes At The Genome-Wide Scale

Noninvasive Diagnosis Of Fetal Aneuploidy By Sequencing

Proteins

Transposase And Method Of Gene Modification

Multipotent Stem Cells And Uses Thereof

Space Efficient Polymer Sets

Method Of Determining The Nucleotide Sequence Of Oligonucleotides And Dna Molecules

Computer Systems And Methods For Analyzing Experiment Design

Aberrantly Methylated Genes In Pancreatic Cancer

Engineered Protein Kinases Which Can Utilize Modified Nucleotide Triphosphate Substrates

Method Of Determining The Nucleotide Sequence Of Oligonucleotides And Dna Molecules

Uses Of Histone Acetyltransferase Activators

Nanopore Based Sequencer

Methods And Systems For Detecting Genetic Mutations

Methods And Apparatuses For Analyzing Polynucleotide Sequences

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

Method Of Determining The Nucleotide Sequence Of Oligonucleotides And Dna Molecules

Transposase And Method Of Gene Modification

Methods For Detection Of Genetic Disorders

Rapid Analysis Of Variations In A Genome

Method For Controlling Tumor Growth, Angiogenesis And Metastasis Using Immunoglobulin Containing And Proline Rich Receptor-1 (Igpr-1)

Il-1 Gene Cluster And Associated Inflammatory Polymorphisms And Haplotypes

Multipotent Stem Cells And Uses Thereof

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

Protection Of Cells From Alu-Rna-Induced Degenereation And Inhibitors For Protecting Cells

Methods Of Producing Hybrid Antibodies

Protection Of Cells From Alu-Rna-Induced Degeneration And Inhibitors For Protecting Cells

Functionalization Of And Use Of Functionalized Second Harmonic Generating Nanoprobes

Transposon System And Methods Of Use

Methods For Detection Of Genetic Disorders

Short Cycle Methods For Sequencing Polynucleotides

Method For Genetic Detection Using Interspersed Genetic Elements: A Multiplexed Dna Analysis System

Noninvasive Diagnosis Of Fetal Aneuploidy By Sequencing

Diagnosis And Treatment Of Herpes Simplex Virus Diseases

Rapid Analysis Of Variations In A Genome

Methods For Detection Of Genetic Disorders

Second Harmonic Imaging Nanoprobes And Techniques For Use Thereof

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/35057062

DOI

http://dx.doi.org/10.1038/35057062

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042854081

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11237011

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Download the RDF metadata as: json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/35057062'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/35057062'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/35057062'

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This table displays all metadata directly associated to this object as RDF triples.

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469	″	schema:description	The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.
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Initial sequencing and analysis of the human genome View Full Text

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