Post-transcriptional gene silencing by double-stranded RNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-02

AUTHORS

S M Hammond, A A Caudy, G J Hannon

ABSTRACT

Imagine being able to knock out your favourite gene with only a day's work. Not just in one model system, but in virtually any organism: plants, flies, mice or cultured cells. This sort of experimental dream might one day become reality as we learn to harness the power of RNA interference, the process by which double-stranded RNA induces the silencing of homologous endogenous genes. How this phenomenon works is slowly becoming clear, and might help us to develop an effortless tool to probe gene function in cells and animals. More... »

PAGES

110

References to SciGraph publications

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  • Journal

    TITLE

    Nature Reviews Genetics

    ISSUE

    2

    VOLUME

    2

    Author Affiliations

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/35052556

    DOI

    http://dx.doi.org/10.1038/35052556

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1002056710

    PUBMED

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