Enabling the chemistry of life View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-01

AUTHORS

C Walsh

ABSTRACT

Enzymes are the subset of proteins that catalyse the chemistry of life, transforming both macromolecular substrates and small molecules. The precise three-dimensional architecture of enzymes permits almost unerring selectivity in physical and chemical steps to impose remarkable rate accelerations and specificity in product-determining reactions. Many enzymes are members of families that carry out related chemical transformations and offer opportunities for directed in vitro evolution, to tailor catalytic properties to particular functions. More... »

PAGES

226-231

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/35051697

DOI

http://dx.doi.org/10.1038/35051697

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053324592

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11196650


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