The origins, patterns and implications of human spontaneous mutation View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-10

AUTHORS

J F Crow

ABSTRACT

The germline mutation rate in human males, especially older males, is generally much higher than in females, mainly because in males there are many more germ-cell divisions. However, there are some exceptions and many variations. Base substitutions, insertion-deletions, repeat expansions and chromosomal changes each follow different rules. Evidence from evolutionary sequence data indicates that the overall rate of deleterious mutation may be high enough to have a large effect on human well-being. But there are ways in which the impact of deleterious mutations can be mitigated. More... »

PAGES

40-47

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/35049558

    DOI

    http://dx.doi.org/10.1038/35049558

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1018255526

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11262873


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    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/35049558'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/35049558'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/35049558'

    RDF/XML is a standard XML format for linked data.

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