The mitochondrion in apoptosis: how Pandora's box opens View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-01

AUTHORS

Naoufal Zamzami, Guido Kroemer

ABSTRACT

There is widespread agreement that mitochondria have a function in apoptosis, but the mechanisms behind their involvement remain controversial. Here we suggest that opening of a multiprotein complex called the mitochondrial permeability transition pore complex is sufficient (and, usually, necessary) for triggering apoptosis.

PAGES

67-71

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/35048073

DOI

http://dx.doi.org/10.1038/35048073

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053037482

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11413468


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