Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1991-04

AUTHORS

O Chisaka, M R Capecchi

ABSTRACT

Gene targeting in mouse embryo-derived stem cells has been used to disrupt the homeobox gene hox-1.5. Mice heterozygous at the hox-1.5 locus appear normal, whereas hox-1.5-/hox-1.5- mice die at or shortly after birth. These homozygotes are athymic, aparathyroid, have reduced thyroid and submaxillary tissue and exhibit a wide range of throat abnormalities. In addition, they often feature defects of the heart and arteries as well as craniofacial abnormalities. These deficiencies are remarkably similar to the pathology of the human congenital disorder DiGeorge's syndrome. More... »

PAGES

473-479

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/350473a0

DOI

http://dx.doi.org/10.1038/350473a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000427753

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1673020


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Abnormalities, Multiple", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals, Newborn", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Arteries", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bone and Bones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cartilage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Embryonic and Fetal Development", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Esophagus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Homeobox", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heart Defects, Congenital", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Homozygote", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Morphogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organ Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Parathyroid Glands", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Pharynx", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phenotype", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Restriction Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thymus Gland", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Thyroid Gland", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Trachea", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "University of Utah", 
          "id": "https://www.grid.ac/institutes/grid.223827.e", 
          "name": [
            "Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City 84112."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chisaka", 
        "givenName": "O", 
        "id": "sg:person.01114445340.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114445340.14"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Capecchi", 
        "givenName": "M R", 
        "id": "sg:person.0612270466.89", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612270466.89"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/324662a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001762188", 
          "https://doi.org/10.1038/324662a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/324662a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001762188", 
          "https://doi.org/10.1038/324662a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(90)90385-r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005958333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.2.7.901", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008418443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/325021b0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008891611", 
          "https://doi.org/10.1038/325021b0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/276565a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009007731", 
          "https://doi.org/10.1038/276565a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/tera.1420220306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013756994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/tera.1420220306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013756994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/287795a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017279186", 
          "https://doi.org/10.1038/287795a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ar.1092250306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018246230"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1749-6632.1990.tb13214.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024196049"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/336348a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024391427", 
          "https://doi.org/10.1038/336348a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/346847a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027532470", 
          "https://doi.org/10.1038/346847a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/17.24.10385", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028581059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.1.10.1268", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030359843"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/308428a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032105729", 
          "https://doi.org/10.1038/308428a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(84)90262-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032942613"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0888-7543(90)90185-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034940159"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(87)90646-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039136966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(84)90371-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040313878"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/309255a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040988478", 
          "https://doi.org/10.1038/309255a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-9525(89)90029-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042901717"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-419x(89)90033-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045655399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-419x(89)90033-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045655399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/335025a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047320553", 
          "https://doi.org/10.1038/335025a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(89)90912-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048713376"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(84)90370-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050957184"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gad.2.7.773", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051295005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1974085", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062515811"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.221.4605.23", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062527239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2660260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062549377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2884726", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062570104"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3898362", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062622093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.6844926", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062640995"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074999859", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077359029", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078856437", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1989.tb03534.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1079046848"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079444188", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079447290", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079603262", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1991-04", 
    "datePublishedReg": "1991-04-01", 
    "description": "Gene targeting in mouse embryo-derived stem cells has been used to disrupt the homeobox gene hox-1.5. Mice heterozygous at the hox-1.5 locus appear normal, whereas hox-1.5-/hox-1.5- mice die at or shortly after birth. These homozygotes are athymic, aparathyroid, have reduced thyroid and submaxillary tissue and exhibit a wide range of throat abnormalities. In addition, they often feature defects of the heart and arteries as well as craniofacial abnormalities. These deficiencies are remarkably similar to the pathology of the human congenital disorder DiGeorge's syndrome.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/350473a0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6318", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "350"
      }
    ], 
    "name": "Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5", 
    "pagination": "473-479", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "02091dc90f1db52793e98e9801c4eacfef5ccce100cb808a8a689b553c53f443"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "1673020"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/350473a0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1000427753"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/350473a0", 
      "https://app.dimensions.ai/details/publication/pub.1000427753"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T19:44", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000421.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/350473a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/350473a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/350473a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/350473a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/350473a0'


 

This table displays all metadata directly associated to this object as RDF triples.

280 TRIPLES      21 PREDICATES      89 URIs      43 LITERALS      31 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/350473a0 schema:about N0168b98bdb12433da2514bb8168aca6d
2 N05113bb783d64cf6a2f6b846565345d5
3 N119f42abbcbf42f4b19b575adb91e6e3
4 N3a37a5827ff943f1a4e90ae4cbc7a617
5 N43b78d6f56684bd9bba4f0abf4fd3837
6 N5d118b5763964dab9c35958ad99ec2f9
7 N6983da0e259d45c48abc4b297d7d89b0
8 N6d851efda9ee44c896118e23ec5b8f8b
9 N74b8a300fdbb466ab160a59f564bdb7f
10 N765211d8bbb0407fb38790ce8bb209bc
11 N7b9277d6059840ee83a4953d09ffeae2
12 N80b92688133d4f05a060f54ab80eb8dd
13 Na6d2f7a5d21a450d8aadd2ea5b08b064
14 Na7bdab8d8ff14b33ae2336ba1b7d4109
15 Naa099a7c11074061bec5832e2524e5bc
16 Nb8a269d957ef40bd9c69c89cf2d1bc3b
17 Nbdd2ab5ba4f240c0a4339a38a15655c6
18 Nc470448919074ed0be3bea960ed4c0f6
19 Nca698f6b86c444cbab974d14941b3d29
20 Ndc854879fc1b47cb94e9ba0f4e374d73
21 Nddb0e50038434ce0ad4d30e335124aa0
22 Nde7e3cd91c524a11b7d7fa72f73221b7
23 anzsrc-for:06
24 anzsrc-for:0604
25 schema:author N377c7d3c407747088fa17d0a2ce475ac
26 schema:citation sg:pub.10.1038/276565a0
27 sg:pub.10.1038/287795a0
28 sg:pub.10.1038/308428a0
29 sg:pub.10.1038/309255a0
30 sg:pub.10.1038/324662a0
31 sg:pub.10.1038/325021b0
32 sg:pub.10.1038/335025a0
33 sg:pub.10.1038/336348a0
34 sg:pub.10.1038/346847a0
35 https://app.dimensions.ai/details/publication/pub.1074999859
36 https://app.dimensions.ai/details/publication/pub.1077359029
37 https://app.dimensions.ai/details/publication/pub.1078856437
38 https://app.dimensions.ai/details/publication/pub.1079444188
39 https://app.dimensions.ai/details/publication/pub.1079447290
40 https://app.dimensions.ai/details/publication/pub.1079603262
41 https://doi.org/10.1002/ar.1092250306
42 https://doi.org/10.1002/j.1460-2075.1989.tb03534.x
43 https://doi.org/10.1002/tera.1420220306
44 https://doi.org/10.1016/0092-8674(84)90262-9
45 https://doi.org/10.1016/0092-8674(84)90370-2
46 https://doi.org/10.1016/0092-8674(84)90371-4
47 https://doi.org/10.1016/0092-8674(87)90646-5
48 https://doi.org/10.1016/0092-8674(89)90912-4
49 https://doi.org/10.1016/0092-8674(90)90385-r
50 https://doi.org/10.1016/0168-9525(89)90029-2
51 https://doi.org/10.1016/0304-419x(89)90033-4
52 https://doi.org/10.1016/0888-7543(90)90185-w
53 https://doi.org/10.1093/nar/17.24.10385
54 https://doi.org/10.1101/gad.1.10.1268
55 https://doi.org/10.1101/gad.2.7.773
56 https://doi.org/10.1101/gad.2.7.901
57 https://doi.org/10.1111/j.1749-6632.1990.tb13214.x
58 https://doi.org/10.1126/science.1974085
59 https://doi.org/10.1126/science.221.4605.23
60 https://doi.org/10.1126/science.2660260
61 https://doi.org/10.1126/science.2884726
62 https://doi.org/10.1126/science.3898362
63 https://doi.org/10.1126/science.6844926
64 schema:datePublished 1991-04
65 schema:datePublishedReg 1991-04-01
66 schema:description Gene targeting in mouse embryo-derived stem cells has been used to disrupt the homeobox gene hox-1.5. Mice heterozygous at the hox-1.5 locus appear normal, whereas hox-1.5-/hox-1.5- mice die at or shortly after birth. These homozygotes are athymic, aparathyroid, have reduced thyroid and submaxillary tissue and exhibit a wide range of throat abnormalities. In addition, they often feature defects of the heart and arteries as well as craniofacial abnormalities. These deficiencies are remarkably similar to the pathology of the human congenital disorder DiGeorge's syndrome.
67 schema:genre research_article
68 schema:inLanguage en
69 schema:isAccessibleForFree false
70 schema:isPartOf N2b08fb038bd3410eaf9625ade4d99fd8
71 Ne2e985988dd74d998dcfa53920ec824a
72 sg:journal.1018957
73 schema:name Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5
74 schema:pagination 473-479
75 schema:productId N01f92965acff4b79904fe02ab3d5b5f1
76 N1e3c65d20b204e039fe3dd4f26ad90e9
77 N4499c18cc55c471e8e0ecb560859dbc7
78 Nc5734a7f411a4cef9161d04223bab503
79 Nffd62103461e4885b097afd4ffed8513
80 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000427753
81 https://doi.org/10.1038/350473a0
82 schema:sdDatePublished 2019-04-10T19:44
83 schema:sdLicense https://scigraph.springernature.com/explorer/license/
84 schema:sdPublisher Ncf97223d88c34cf2a6f637de62c72b1d
85 schema:url http://www.nature.com/articles/350473a0
86 sgo:license sg:explorer/license/
87 sgo:sdDataset articles
88 rdf:type schema:ScholarlyArticle
89 N0168b98bdb12433da2514bb8168aca6d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Trachea
91 rdf:type schema:DefinedTerm
92 N01f92965acff4b79904fe02ab3d5b5f1 schema:name dimensions_id
93 schema:value pub.1000427753
94 rdf:type schema:PropertyValue
95 N05113bb783d64cf6a2f6b846565345d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
96 schema:name Genes, Homeobox
97 rdf:type schema:DefinedTerm
98 N119f42abbcbf42f4b19b575adb91e6e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
99 schema:name Animals, Newborn
100 rdf:type schema:DefinedTerm
101 N1e3c65d20b204e039fe3dd4f26ad90e9 schema:name doi
102 schema:value 10.1038/350473a0
103 rdf:type schema:PropertyValue
104 N2b08fb038bd3410eaf9625ade4d99fd8 schema:issueNumber 6318
105 rdf:type schema:PublicationIssue
106 N377c7d3c407747088fa17d0a2ce475ac rdf:first sg:person.01114445340.14
107 rdf:rest N4dc995bad61d407c81162097f0a54669
108 N3a37a5827ff943f1a4e90ae4cbc7a617 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
109 schema:name Homozygote
110 rdf:type schema:DefinedTerm
111 N43b78d6f56684bd9bba4f0abf4fd3837 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Gene Expression
113 rdf:type schema:DefinedTerm
114 N4499c18cc55c471e8e0ecb560859dbc7 schema:name readcube_id
115 schema:value 02091dc90f1db52793e98e9801c4eacfef5ccce100cb808a8a689b553c53f443
116 rdf:type schema:PropertyValue
117 N4dc995bad61d407c81162097f0a54669 rdf:first sg:person.0612270466.89
118 rdf:rest rdf:nil
119 N5d118b5763964dab9c35958ad99ec2f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Morphogenesis
121 rdf:type schema:DefinedTerm
122 N6983da0e259d45c48abc4b297d7d89b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Abnormalities, Multiple
124 rdf:type schema:DefinedTerm
125 N6d851efda9ee44c896118e23ec5b8f8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Restriction Mapping
127 rdf:type schema:DefinedTerm
128 N74b8a300fdbb466ab160a59f564bdb7f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Bone and Bones
130 rdf:type schema:DefinedTerm
131 N765211d8bbb0407fb38790ce8bb209bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Phenotype
133 rdf:type schema:DefinedTerm
134 N7b9277d6059840ee83a4953d09ffeae2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Arteries
136 rdf:type schema:DefinedTerm
137 N80b92688133d4f05a060f54ab80eb8dd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Organ Specificity
139 rdf:type schema:DefinedTerm
140 Na6d2f7a5d21a450d8aadd2ea5b08b064 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Esophagus
142 rdf:type schema:DefinedTerm
143 Na7bdab8d8ff14b33ae2336ba1b7d4109 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Thyroid Gland
145 rdf:type schema:DefinedTerm
146 Naa099a7c11074061bec5832e2524e5bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
147 schema:name Mice
148 rdf:type schema:DefinedTerm
149 Nb8a269d957ef40bd9c69c89cf2d1bc3b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
150 schema:name Heart Defects, Congenital
151 rdf:type schema:DefinedTerm
152 Nbdd2ab5ba4f240c0a4339a38a15655c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
153 schema:name Parathyroid Glands
154 rdf:type schema:DefinedTerm
155 Nc470448919074ed0be3bea960ed4c0f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
156 schema:name Embryonic and Fetal Development
157 rdf:type schema:DefinedTerm
158 Nc5734a7f411a4cef9161d04223bab503 schema:name nlm_unique_id
159 schema:value 0410462
160 rdf:type schema:PropertyValue
161 Nca698f6b86c444cbab974d14941b3d29 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Thymus Gland
163 rdf:type schema:DefinedTerm
164 Ncf97223d88c34cf2a6f637de62c72b1d schema:name Springer Nature - SN SciGraph project
165 rdf:type schema:Organization
166 Ndc854879fc1b47cb94e9ba0f4e374d73 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Cartilage
168 rdf:type schema:DefinedTerm
169 Nddb0e50038434ce0ad4d30e335124aa0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Animals
171 rdf:type schema:DefinedTerm
172 Nde7e3cd91c524a11b7d7fa72f73221b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Pharynx
174 rdf:type schema:DefinedTerm
175 Ne2e985988dd74d998dcfa53920ec824a schema:volumeNumber 350
176 rdf:type schema:PublicationVolume
177 Nffd62103461e4885b097afd4ffed8513 schema:name pubmed_id
178 schema:value 1673020
179 rdf:type schema:PropertyValue
180 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
181 schema:name Biological Sciences
182 rdf:type schema:DefinedTerm
183 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
184 schema:name Genetics
185 rdf:type schema:DefinedTerm
186 sg:journal.1018957 schema:issn 0090-0028
187 1476-4687
188 schema:name Nature
189 rdf:type schema:Periodical
190 sg:person.01114445340.14 schema:affiliation https://www.grid.ac/institutes/grid.223827.e
191 schema:familyName Chisaka
192 schema:givenName O
193 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114445340.14
194 rdf:type schema:Person
195 sg:person.0612270466.89 schema:familyName Capecchi
196 schema:givenName M R
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0612270466.89
198 rdf:type schema:Person
199 sg:pub.10.1038/276565a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009007731
200 https://doi.org/10.1038/276565a0
201 rdf:type schema:CreativeWork
202 sg:pub.10.1038/287795a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017279186
203 https://doi.org/10.1038/287795a0
204 rdf:type schema:CreativeWork
205 sg:pub.10.1038/308428a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032105729
206 https://doi.org/10.1038/308428a0
207 rdf:type schema:CreativeWork
208 sg:pub.10.1038/309255a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040988478
209 https://doi.org/10.1038/309255a0
210 rdf:type schema:CreativeWork
211 sg:pub.10.1038/324662a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001762188
212 https://doi.org/10.1038/324662a0
213 rdf:type schema:CreativeWork
214 sg:pub.10.1038/325021b0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008891611
215 https://doi.org/10.1038/325021b0
216 rdf:type schema:CreativeWork
217 sg:pub.10.1038/335025a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047320553
218 https://doi.org/10.1038/335025a0
219 rdf:type schema:CreativeWork
220 sg:pub.10.1038/336348a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024391427
221 https://doi.org/10.1038/336348a0
222 rdf:type schema:CreativeWork
223 sg:pub.10.1038/346847a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027532470
224 https://doi.org/10.1038/346847a0
225 rdf:type schema:CreativeWork
226 https://app.dimensions.ai/details/publication/pub.1074999859 schema:CreativeWork
227 https://app.dimensions.ai/details/publication/pub.1077359029 schema:CreativeWork
228 https://app.dimensions.ai/details/publication/pub.1078856437 schema:CreativeWork
229 https://app.dimensions.ai/details/publication/pub.1079444188 schema:CreativeWork
230 https://app.dimensions.ai/details/publication/pub.1079447290 schema:CreativeWork
231 https://app.dimensions.ai/details/publication/pub.1079603262 schema:CreativeWork
232 https://doi.org/10.1002/ar.1092250306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018246230
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1002/j.1460-2075.1989.tb03534.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1079046848
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1002/tera.1420220306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013756994
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1016/0092-8674(84)90262-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032942613
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1016/0092-8674(84)90370-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050957184
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1016/0092-8674(84)90371-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040313878
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1016/0092-8674(87)90646-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039136966
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1016/0092-8674(89)90912-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048713376
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1016/0092-8674(90)90385-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1005958333
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1016/0168-9525(89)90029-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042901717
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1016/0304-419x(89)90033-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045655399
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1016/0888-7543(90)90185-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1034940159
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1093/nar/17.24.10385 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028581059
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1101/gad.1.10.1268 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030359843
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1101/gad.2.7.773 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051295005
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1101/gad.2.7.901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008418443
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1111/j.1749-6632.1990.tb13214.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024196049
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1126/science.1974085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062515811
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1126/science.221.4605.23 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062527239
269 rdf:type schema:CreativeWork
270 https://doi.org/10.1126/science.2660260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062549377
271 rdf:type schema:CreativeWork
272 https://doi.org/10.1126/science.2884726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062570104
273 rdf:type schema:CreativeWork
274 https://doi.org/10.1126/science.3898362 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062622093
275 rdf:type schema:CreativeWork
276 https://doi.org/10.1126/science.6844926 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062640995
277 rdf:type schema:CreativeWork
278 https://www.grid.ac/institutes/grid.223827.e schema:alternateName University of Utah
279 schema:name Howard Hughes Medical Institute, Department of Human Genetics, University of Utah School of Medicine, Salt Lake City 84112.
280 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...