Nuclear compartmentalization and gene activity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-11

AUTHORS

Claire Francastel, Dirk Schübeler, David I. K. Martin, Mark Groudine

ABSTRACT

The regulated expression of genes during development and differentiation is influenced by the availability of regulatory proteins and accessibility of the DNA to the transcriptional apparatus. There is growing evidence that the transcriptional activity of genes is influenced by nuclear organization, which itself changes during differentiation. How do these changes in nuclear organization help to establish specific patterns of gene expression? More... »

PAGES

137-143

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/35040083

DOI

http://dx.doi.org/10.1038/35040083

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1007304424

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11253366


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