Genomics, gene expression and DNA arrays View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2000-06

AUTHORS

D J Lockhart, E A Winzeler

ABSTRACT

Experimental genomics in combination with the growing body of sequence information promise to revolutionize the way cells and cellular processes are studied. Information on genomic sequence can be used experimentally with high-density DNA arrays that allow complex mixtures of RNA and DNA to be interrogated in a parallel and quantitative fashion. DNA arrays can be used for many different purposes, most prominently to measure levels of gene expression (messenger RNA abundance) for tens of thousands of genes simultaneously. Measurements of gene expression and other applications of arrays embody much of what is implied by the term 'genomics'; they are broad in scope, large in scale, and take advantage of all available sequence information for experimental design and data interpretation in pursuit of biological understanding. More... »

PAGES

827-836

References to SciGraph publications

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  • Journal

    TITLE

    Nature

    ISSUE

    6788

    VOLUME

    405

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/35015701

    DOI

    http://dx.doi.org/10.1038/35015701

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1028135585

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/10866209


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    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/35015701'

    Turtle is a human-readable linked data format.

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    RDF/XML is a standard XML format for linked data.

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