A sodium-potassium switch in the formation of four-stranded G4-DNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-03

AUTHORS

D Sen, W Gilbert

ABSTRACT

Single-stranded complex guanine-rich DNA sequences from chromosomal telomeres and elsewhere can associate to form stable parallel four-stranded structures termed G4-DNA by a process that is anomalously dependent on the particular alkali metal cation that is present. The anomaly, which is not found in the formation of G4-DNA by oligonucleotides containing short, single runs of three or more guanines, is caused by potassium cations excessively stabilizing fold-back intermediate structures, or pathway by-products. More... »

PAGES

410-414

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/344410a0

DOI

http://dx.doi.org/10.1038/344410a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008619790

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2320109


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