Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1990-01

AUTHORS

Joseph A. Piccirilli, Steven A. Benner, Tilman Krauch, Simon E. Moroney, Steven A. Benner

ABSTRACT

A new Watson-Crick base pair, with a hydrogen bonding pattern different from that in the A.T and G.C base pairs, is incorporated into duplex DNA and RNA by DNA and RNA polymerases and expands the genetic alphabet from 4 to 6 letters. This expansion could lead to RNAs with greater diversity in functional groups and greater catalytic potential. More... »

PAGES

33-37

Journal

TITLE

Nature

ISSUE

6253

VOLUME

343

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/343033a0

    DOI

    http://dx.doi.org/10.1038/343033a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1023013667

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/1688644


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