Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transport View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-06

AUTHORS

R Diaz, L S Mayorga, P J Weidman, J E Rothman, P D Stahl

ABSTRACT

In reconstitution studies N-ethylmaleimide, a sulphydryl alkylating reagent, inhibits both fusion of endocytic vesicles and vesicular transport in the Golgi apparatus. We show here that the same N-ethylmaleimide-sensitive factor that catalyses the vesicle-mediated transport within Golgi stacks is also required for endocytic vesicle fusion. Thus, it is likely that a common mechanism for vesicle fusion exists for both the secretory and endocytic pathways of eukaryotic cells. More... »

PAGES

398-400

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/339398a0

DOI

http://dx.doi.org/10.1038/339398a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1025679088

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2725659


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