The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1989-03

AUTHORS

Daniel Finley, Bonnie Bartel, Alexander Varshavsky

ABSTRACT

Three of the four yeast ubiquitin genes encode hybrid proteins which are cleaved to yield ubiquitin and previously unidentified ribosomal proteins. The transient association between ubiquitin and these proteins promotes their incorporation into nascent ribosomes and is required for efficient ribosome biogenesis. These results suggest a novel 'chaperone' function for ubiquitin, in which its covalent association with other proteins promotes the formation of specific cellular structures. More... »

PAGES

394-401

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/338394a0

DOI

http://dx.doi.org/10.1038/338394a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048837529

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2538753


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