RNA evolution and the origins of life View Full Text


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Article Info

DATE

1989-03

AUTHORS

Gerald F. Joyce

ABSTRACT

The evolution of RNA is likely to have played an important role in the very early history of life on Earth but it is doubtful that life began with RNA. Consideration of what came before RNA must take into account relevant information from geochemistry, prebiotic chemistry and nucleic acid biochemistry.

PAGES

217-224

References to SciGraph publications

  • 1986-02. Origin of life: The RNA world in NATURE
  • 1986-09. Non-enzymatic cleavage and ligation of RNAs complementary to a plant virus satellite RNA in NATURE
  • 1988-09. The chemical logic of a minimum protocell in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 1986-03. Did template-directed nucleation precede molecular replication? in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 1988-09. High resolution structure of the RNA duplex [U(U-A)6A]2 in NATURE
  • 1976-06. Coenzymes as fossils of an earlier metabolic state in JOURNAL OF MOLECULAR EVOLUTION
  • 1978-12. HCN: A plausible source of purines, pyrimidines and amino acids on the primitive earth in JOURNAL OF MOLECULAR EVOLUTION
  • 1988-02. Impact frustration of the origin of life in NATURE
  • 1974-12. Chemial evolution in JOURNAL OF MOLECULAR EVOLUTION
  • 1984-12. The improbability of prebiotic nucleic acid synthesis in ORIGINS OF LIFE
  • 1972-02. RNA Double Helix and the Evolution of the 3′,5′ Linkage in NATURE
  • 1967-11. Model for Origin of Monosaccharides in NATURE
  • 1961-04. Comets and the Formation of Biochemical Compounds on the Primitive Earth in NATURE
  • 1987-06. The triose model: Glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 1985-12. The photochemistry of biogenic gases in the early and present atmosphere in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 1973-12. Catalysts for the self-polymerization of adenosine cyclic 2′,3′-phosphate in JOURNAL OF MOLECULAR EVOLUTION
  • 1984-12. Chiral versus chemical evolutions and the appearance of life in ORIGINS OF LIFE
  • 1967-11. Model for Origin of Monosaccharides: Synthesis of Sugars in Potentially Prebiotic Conditions in NATURE
  • 1976-09. Possible pathway for prebiotic uracil synthesis by photodehydrogenation in NATURE
  • 1980-03. Origin of life: Consideration of alternatives to proteins and nucleic acids in JOURNAL OF MOLECULAR EVOLUTION
  • 1988-12. Cyclization of nucleotide analogues as an obstacle to polymerization in JOURNAL OF MOLECULAR EVOLUTION
  • 1975-12. Formation of nucleoside 5′-polyphosphates from nucleotides and trimetaphosphate in JOURNAL OF MOLECULAR EVOLUTION
  • 1978-09. Chemical evolution and the origin of life. in SCIENTIFIC AMERICAN
  • 1961-09. Mechanism of Synthesis of Adenine from Hydrogen Cyanide under Possible Primitive Earth Conditions in NATURE
  • 1982-09. Acceleration of HCN oligomerization by formaldehyde and related compounds: Implications for prebiotic syntheses in JOURNAL OF MOLECULAR EVOLUTION
  • 1982-09. A model for the origin of life in JOURNAL OF MOLECULAR EVOLUTION
  • 1984-08. Chiral selection in poly(C)-directed synthesis of oligo(G) in NATURE
  • 1987-09. Energy yields for hydrogen cyanide and formaldehyde syntheses: The hcn and amino acid concentrations in the primitive ocean in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 1971-10. Selforganization of matter and the evolution of biological macromolecules in THE SCIENCE OF NATURE
  • 1983-09. Prebiotic synthesis in atmospheres containing CH4, CO, and CO2 in JOURNAL OF MOLECULAR EVOLUTION
  • 1987-02. The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing in NATURE
  • 1973-06. Further studies of urea-catalyzed phosphorylation reactions in JOURNAL OF MOLECULAR EVOLUTION
  • 1981-12. Nonenzymatic photophosphorylation with visible light in THE SCIENCE OF NATURE
  • 1987-08. A small catalytic oligoribonucleotide in NATURE
  • 1985-06. Rna catalysis and the origin of life in ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
  • 1972-05. Prebiotic Phosphorylation of Thymidine at 65° C in Simulated Desert Conditions in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/338217a0

    DOI

    http://dx.doi.org/10.1038/338217a0

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2466202


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