The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-09

AUTHORS

B Chabot, D A Stephenson, V M Chapman, P Besmer, A Bernstein

ABSTRACT

Mice carrying mutations at the W locus located on chromosome 5 are characterized by severe macrocytic anaemia, lack of hair pigmentation and sterility. Mutations at this locus appear to affect the proliferation and/or migration of cells during early embryogenesis and result in an intrinsic defect in the haematopoietic stem cell hierarchy. An understanding of the molecular basis of the complex and pleiotropic phenotype in W mutant mice would thus provide insights into the important developmental processes of gametogenesis, melanogenesis and haematopoiesis. Here we show that the mouse mutant W has a deletion of the c-kit proto-oncogene. Interspecific backcross analysis demonstrates that the W locus is very tightly linked to c-kit and that the two loci cannot be segregated at this level of analysis. c-kit is the cellular homologue of the oncogene v-kit of the HZ4 feline sarcoma virus and encodes a transmembrane protein tyrosine kinase receptor that is structurally similar to the receptors for colony-stimulating factor-1 (CSF-1) and platelet derived growth factor. The co-localization of c-kit with W provides a molecular entry into this important region of the mouse genome. In addition, these observations provide the first example of a germ-line mutation in a mammalian proto-oncogene and implicate the c-kit gene as a candidate for the W locus. More... »

PAGES

88-89

Journal

TITLE

Nature

ISSUE

6185

VOLUME

335

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/335088a0

DOI

http://dx.doi.org/10.1038/335088a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1037763215

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2457811


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membrane Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice, Mutant Strains", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein-Tyrosine Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogene Proteins c-kit", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Proto-Oncogenes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Cell Surface", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Mount Sinai Hospital", 
          "id": "https://www.grid.ac/institutes/grid.416166.2", 
          "name": [
            "Division of Molecular and Developmental Biology, Mount Sinai Hospital Research Institute, Toronto, Ontario, Canada."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chabot", 
        "givenName": "B", 
        "id": "sg:person.01050047210.95", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050047210.95"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Stephenson", 
        "givenName": "D A", 
        "type": "Person"
      }, 
      {
        "familyName": "Chapman", 
        "givenName": "V M", 
        "type": "Person"
      }, 
      {
        "familyName": "Besmer", 
        "givenName": "P", 
        "id": "sg:person.01166442246.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166442246.38"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Bernstein", 
        "givenName": "A", 
        "id": "sg:person.01207401047.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207401047.34"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/s0092-8674(85)80047-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019129197"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-9525(88)90044-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027569100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-9525(88)90044-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027569100"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/320415a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048357643", 
          "https://doi.org/10.1038/320415a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00291740", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050913708", 
          "https://doi.org/10.1007/bf00291740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s001667230002098x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053874040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s001667230002098x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053874040"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0016672300001555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053968198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s0016672300001555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053968198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.144.3620.844", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062482656"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1987.tb02655.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078849474"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1988.tb02907.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1078871156"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0065-2660(08)60549-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1080028381"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080988070", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1988-09", 
    "datePublishedReg": "1988-09-01", 
    "description": "Mice carrying mutations at the W locus located on chromosome 5 are characterized by severe macrocytic anaemia, lack of hair pigmentation and sterility. Mutations at this locus appear to affect the proliferation and/or migration of cells during early embryogenesis and result in an intrinsic defect in the haematopoietic stem cell hierarchy. An understanding of the molecular basis of the complex and pleiotropic phenotype in W mutant mice would thus provide insights into the important developmental processes of gametogenesis, melanogenesis and haematopoiesis. Here we show that the mouse mutant W has a deletion of the c-kit proto-oncogene. Interspecific backcross analysis demonstrates that the W locus is very tightly linked to c-kit and that the two loci cannot be segregated at this level of analysis. c-kit is the cellular homologue of the oncogene v-kit of the HZ4 feline sarcoma virus and encodes a transmembrane protein tyrosine kinase receptor that is structurally similar to the receptors for colony-stimulating factor-1 (CSF-1) and platelet derived growth factor. The co-localization of c-kit with W provides a molecular entry into this important region of the mouse genome. In addition, these observations provide the first example of a germ-line mutation in a mammalian proto-oncogene and implicate the c-kit gene as a candidate for the W locus.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/335088a0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6185", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "335"
      }
    ], 
    "name": "The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus", 
    "pagination": "88-89", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "b3e4708fb9bb9266e1303d449da179c8af5fe1ad1bb6c7e29330ac11cc4a4392"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "2457811"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/335088a0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1037763215"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/335088a0", 
      "https://app.dimensions.ai/details/publication/pub.1037763215"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:04", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000425.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/335088a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/335088a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/335088a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/335088a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/335088a0'


 

This table displays all metadata directly associated to this object as RDF triples.

169 TRIPLES      21 PREDICATES      51 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/335088a0 schema:about N16ebb6cfba7247e29eda4d1b5cdc7fb9
2 N2c232dd8bcef404686e4320f06b96e99
3 N3f9060cdacb6407ea7094b1f9171fea7
4 N47f3e451b5d04ed497b83d387b98a4fe
5 N4a246117e5de443bb8962da25c907e85
6 N5d77c7092d44465cb3b333876ea1bb07
7 N66314ba45fca44cf94b0117e2d996850
8 N6d80f8d9876e414aa421afe03cd8d4e2
9 N6ef7034a061a4656b08d7549ff4f7495
10 N7dc70e7cabc84b5d857989e6d8a3f3fa
11 Nc820b21060cf4f6590de2edb7853512a
12 anzsrc-for:06
13 anzsrc-for:0604
14 schema:author N5b3b09fc81e743d9a53c847d477d0f06
15 schema:citation sg:pub.10.1007/bf00291740
16 sg:pub.10.1038/320415a0
17 https://app.dimensions.ai/details/publication/pub.1080988070
18 https://doi.org/10.1002/j.1460-2075.1987.tb02655.x
19 https://doi.org/10.1002/j.1460-2075.1988.tb02907.x
20 https://doi.org/10.1016/0168-9525(88)90044-3
21 https://doi.org/10.1016/s0065-2660(08)60549-0
22 https://doi.org/10.1016/s0092-8674(85)80047-7
23 https://doi.org/10.1017/s0016672300001555
24 https://doi.org/10.1017/s001667230002098x
25 https://doi.org/10.1126/science.144.3620.844
26 schema:datePublished 1988-09
27 schema:datePublishedReg 1988-09-01
28 schema:description Mice carrying mutations at the W locus located on chromosome 5 are characterized by severe macrocytic anaemia, lack of hair pigmentation and sterility. Mutations at this locus appear to affect the proliferation and/or migration of cells during early embryogenesis and result in an intrinsic defect in the haematopoietic stem cell hierarchy. An understanding of the molecular basis of the complex and pleiotropic phenotype in W mutant mice would thus provide insights into the important developmental processes of gametogenesis, melanogenesis and haematopoiesis. Here we show that the mouse mutant W has a deletion of the c-kit proto-oncogene. Interspecific backcross analysis demonstrates that the W locus is very tightly linked to c-kit and that the two loci cannot be segregated at this level of analysis. c-kit is the cellular homologue of the oncogene v-kit of the HZ4 feline sarcoma virus and encodes a transmembrane protein tyrosine kinase receptor that is structurally similar to the receptors for colony-stimulating factor-1 (CSF-1) and platelet derived growth factor. The co-localization of c-kit with W provides a molecular entry into this important region of the mouse genome. In addition, these observations provide the first example of a germ-line mutation in a mammalian proto-oncogene and implicate the c-kit gene as a candidate for the W locus.
29 schema:genre research_article
30 schema:inLanguage en
31 schema:isAccessibleForFree false
32 schema:isPartOf N047b76fb767a4b53afe84f36e18e0b2d
33 Nd09f78dd145043b4a9c38f6154c35f64
34 sg:journal.1018957
35 schema:name The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
36 schema:pagination 88-89
37 schema:productId N610fa44ce031481b8cfba78eae64cb0d
38 N93af6ab771074a40aeec9544bcc9a6d7
39 Naad922ca6697445db7b3c94f2609edb4
40 Nd3fb84d13da341279a35cc5419a441b9
41 Ndadd65f1fd7045c280f954297deccec6
42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037763215
43 https://doi.org/10.1038/335088a0
44 schema:sdDatePublished 2019-04-11T00:04
45 schema:sdLicense https://scigraph.springernature.com/explorer/license/
46 schema:sdPublisher N01e88bf8a6b34b93b9db1503e332c2fa
47 schema:url http://www.nature.com/articles/335088a0
48 sgo:license sg:explorer/license/
49 sgo:sdDataset articles
50 rdf:type schema:ScholarlyArticle
51 N01e88bf8a6b34b93b9db1503e332c2fa schema:name Springer Nature - SN SciGraph project
52 rdf:type schema:Organization
53 N047b76fb767a4b53afe84f36e18e0b2d schema:issueNumber 6185
54 rdf:type schema:PublicationIssue
55 N0e4efc470cb849adb8db46cfd071cd4f rdf:first sg:person.01207401047.34
56 rdf:rest rdf:nil
57 N16ebb6cfba7247e29eda4d1b5cdc7fb9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
58 schema:name Mice
59 rdf:type schema:DefinedTerm
60 N1bca6a9bac9f41a5a201703a439b716f schema:familyName Stephenson
61 schema:givenName D A
62 rdf:type schema:Person
63 N2b5b9fab6b374a239d738b565120d6cb rdf:first N1bca6a9bac9f41a5a201703a439b716f
64 rdf:rest Ne4b0cd738f16438ca58c898a31b6e66c
65 N2c232dd8bcef404686e4320f06b96e99 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
66 schema:name Proto-Oncogene Proteins c-kit
67 rdf:type schema:DefinedTerm
68 N3f9060cdacb6407ea7094b1f9171fea7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Mice, Mutant Strains
70 rdf:type schema:DefinedTerm
71 N47f3e451b5d04ed497b83d387b98a4fe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Proto-Oncogenes
73 rdf:type schema:DefinedTerm
74 N4a246117e5de443bb8962da25c907e85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Chromosome Mapping
76 rdf:type schema:DefinedTerm
77 N5b3b09fc81e743d9a53c847d477d0f06 rdf:first sg:person.01050047210.95
78 rdf:rest N2b5b9fab6b374a239d738b565120d6cb
79 N5d77c7092d44465cb3b333876ea1bb07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
80 schema:name Proto-Oncogene Proteins
81 rdf:type schema:DefinedTerm
82 N610fa44ce031481b8cfba78eae64cb0d schema:name readcube_id
83 schema:value b3e4708fb9bb9266e1303d449da179c8af5fe1ad1bb6c7e29330ac11cc4a4392
84 rdf:type schema:PropertyValue
85 N66314ba45fca44cf94b0117e2d996850 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name Membrane Proteins
87 rdf:type schema:DefinedTerm
88 N6d80f8d9876e414aa421afe03cd8d4e2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Receptors, Cell Surface
90 rdf:type schema:DefinedTerm
91 N6ef7034a061a4656b08d7549ff4f7495 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Animals
93 rdf:type schema:DefinedTerm
94 N7dc70e7cabc84b5d857989e6d8a3f3fa schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
95 schema:name Mutation
96 rdf:type schema:DefinedTerm
97 N93af6ab771074a40aeec9544bcc9a6d7 schema:name dimensions_id
98 schema:value pub.1037763215
99 rdf:type schema:PropertyValue
100 Naad922ca6697445db7b3c94f2609edb4 schema:name nlm_unique_id
101 schema:value 0410462
102 rdf:type schema:PropertyValue
103 Nb98e5c24c8a34ded86f4c9ac46f5a63c rdf:first sg:person.01166442246.38
104 rdf:rest N0e4efc470cb849adb8db46cfd071cd4f
105 Nc820b21060cf4f6590de2edb7853512a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Protein-Tyrosine Kinases
107 rdf:type schema:DefinedTerm
108 Nd09f78dd145043b4a9c38f6154c35f64 schema:volumeNumber 335
109 rdf:type schema:PublicationVolume
110 Nd3fb84d13da341279a35cc5419a441b9 schema:name pubmed_id
111 schema:value 2457811
112 rdf:type schema:PropertyValue
113 Ndadd65f1fd7045c280f954297deccec6 schema:name doi
114 schema:value 10.1038/335088a0
115 rdf:type schema:PropertyValue
116 Ne4b0cd738f16438ca58c898a31b6e66c rdf:first Ne845cf9fc7994a608bd4e51d777a76a0
117 rdf:rest Nb98e5c24c8a34ded86f4c9ac46f5a63c
118 Ne845cf9fc7994a608bd4e51d777a76a0 schema:familyName Chapman
119 schema:givenName V M
120 rdf:type schema:Person
121 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
122 schema:name Biological Sciences
123 rdf:type schema:DefinedTerm
124 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
125 schema:name Genetics
126 rdf:type schema:DefinedTerm
127 sg:journal.1018957 schema:issn 0090-0028
128 1476-4687
129 schema:name Nature
130 rdf:type schema:Periodical
131 sg:person.01050047210.95 schema:affiliation https://www.grid.ac/institutes/grid.416166.2
132 schema:familyName Chabot
133 schema:givenName B
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050047210.95
135 rdf:type schema:Person
136 sg:person.01166442246.38 schema:familyName Besmer
137 schema:givenName P
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01166442246.38
139 rdf:type schema:Person
140 sg:person.01207401047.34 schema:familyName Bernstein
141 schema:givenName A
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207401047.34
143 rdf:type schema:Person
144 sg:pub.10.1007/bf00291740 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050913708
145 https://doi.org/10.1007/bf00291740
146 rdf:type schema:CreativeWork
147 sg:pub.10.1038/320415a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048357643
148 https://doi.org/10.1038/320415a0
149 rdf:type schema:CreativeWork
150 https://app.dimensions.ai/details/publication/pub.1080988070 schema:CreativeWork
151 https://doi.org/10.1002/j.1460-2075.1987.tb02655.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1078849474
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1002/j.1460-2075.1988.tb02907.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1078871156
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/0168-9525(88)90044-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027569100
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/s0065-2660(08)60549-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1080028381
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/s0092-8674(85)80047-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019129197
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1017/s0016672300001555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053968198
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1017/s001667230002098x schema:sameAs https://app.dimensions.ai/details/publication/pub.1053874040
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1126/science.144.3620.844 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062482656
166 rdf:type schema:CreativeWork
167 https://www.grid.ac/institutes/grid.416166.2 schema:alternateName Mount Sinai Hospital
168 schema:name Division of Molecular and Developmental Biology, Mount Sinai Hospital Research Institute, Toronto, Ontario, Canada.
169 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...