Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-07

AUTHORS

J Pelletier, N Sonenberg

ABSTRACT

Poliovirus RNA is naturally uncapped, therefore its translation must proceed via a cap-independent mechanism. Translation initiation on poliovirus RNA occurs by binding of ribosomes to an internal sequence within the 5' noncoding region. This novel mechanism of initiation may explain the disparate translation of several other eukaryotic messenger RNAs.

PAGES

320-325

Journal

TITLE

Nature

ISSUE

6180

VOLUME

334

Author Affiliations

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/334320a0

    DOI

    http://dx.doi.org/10.1038/334320a0

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2839775


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