Function of a yeast TATA element-binding protein in a mammalian transcription system View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-07

AUTHORS

S Buratowski, S Hahn, P A Sharp, L Guarente

ABSTRACT

Saccharomyces cerevisiae contains a protein which is functionally similar to the mammalian TATA element-binding transcription factor, TFIID. The yeast factor substitutes for TFIID in a mammalian RNA polymerase II in vitro transcription system, forms a stable preinitiation complex on the Adenovirus-2 major late promoter, and binds specifically to the TATA boxes of the viral promoter and the yeast CYC1 promoter. Interestingly, the yeast factor promotes initiation at a distance from the TATA element typical of a mammalian system. More... »

PAGES

37-42

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/334037a0

DOI

http://dx.doi.org/10.1038/334037a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040532399

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3290687


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