A novel viral oncogene with structural similarity to phospholipase C View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1988-03

AUTHORS

Bruce J. Mayer, Michinari Hamaguchi, Hidesaburo Hanafusa

ABSTRACT

Numerous oncogenes have been isolated from acutely transforming retroviruses. To date, the products of these viral oncogenes have been protein kinases, nuclear proteins, growth factors, or GTP-binding proteins1,2. We have cloned the previously uncharacterized avian sarcoma virus CT10 and sequenced its genome. This virus encodes a protein, p47gag-crk, that has blocks of sequence similarity to the amino-terminal, non-catalytic region of the non-receptor class of tyrosine kinases. In addition, the structure of p47gag-crk has striking similarity to a 180-amino acid region of bovine brain phospholipase C. Biochemical data suggest that p47gag-crk activates one or several endogenous tyrosine kinases. More... »

PAGES

272-275

References to SciGraph publications

Journal

TITLE

Nature

ISSUE

6161

VOLUME

332

Related Patents

  • Protein Tyrosine Phosphatase Ptp20 And Related Products And Methods
  • Diagnosis And Treatment Of Ptp04 Related Disorders
  • Tyrosine Kinase Associated Protein
  • Tyrosine Kinase Associated Polypeptides
  • Diagnosis And Treatment Of Sad Related Disorders
  • Megakaryocytic Protein Tyrosine Kinase I
  • Screening For Modulators Of Protein Binding Activity; Incubation With At Least One Modulator And Screening For The Components Of The Separated Protein Binding Macromolecular Structure
  • Identification Of Protein Kinase Proteins Which Are Human Orthologues Of The Drosophila Wart Gene (Hwart); Tumor Suppressor Genes
  • Diagnostics And Treatments For Cancers Expressing Tyrosine Phosphorylated Crkl Protein
  • Using 2,5-Bisindol-3-Yl-1,4-Quinone
  • Protein Tyrosine Phosphatase Ptp20 And Related Products And Methods
  • Insulin Diseases; Antidiabetic Agents
  • Expression-Cloning Method For Identifying Target Proteins For Eukaryotic Tyrosine Kinases And Novel Target Protiens
  • Bis-Indolylquinone Compounds
  • Identification And Isolation Of Novel Polypeptides Having Ww Domains And Methods Of Using Same
  • Expression-Cloning Method For Identifying Target Proteins For Eukaryotic Tyrosine Kinases And Novel Target Proteins
  • Gene Therapy In Coronary Angioplasty And Bypass
  • Methods For Disrupting Grb-7 Complexes
  • Contacting Cell That Forms Complex Of Protein Tyrosine Kinase And Grb-2 Adaptor Polypeptide With Compound, Detecting Level Of Complex Present, Comparing To Control; Reduction In Complex Formation Indicates Antiproliferative Agents
  • Expression-Cloning Method For Identifying Target Proteins For Eukaryotic Tyrosine Kinases And Novel Target Proteins
  • Determining Concentration Of Her2/Grb-7 Polypeptide Complex Present In A Biological Sample; Use In Prevention And Treatment Of Oncogenic Disorders Of The Breast
  • Nucleotide Sequences Coding Preferential Polypeptide For Use In The Diagnosis, Treatment And Prevention Of Cell Proliferative Defects
  • Method And Compositions For Inhibition Of Adaptor Protein/Tyrosine Kinase Interactions
  • Diagnosis And Treatment Of Alk-7 Related Disorders
  • Identification And Isolation Of Novel Polypeptides Having Ww Domains And Methods Of Using Same
  • Thrombocytopenia Treatment
  • Methods For Identifying Compounds For Treatment Of Cell Proliferative Disorders Associated With Adaptor Protein Interactions
  • Antibody Recognizing An Antigen Selected From Given Peptide Sequences; End Stage Cirrhosis And Hepatocellular Carcinoma
  • Genetic Engineering; Libraries
  • Methods For Treatment Or Diagnosis Of Diseases Or Disorders Associated With An Apb Domain
  • Nucleic Acids Encoding Proteins For Early Liver Development
  • Diagnosis And Treatment Of Tka-1 Related Disorders
  • Anticarcinogenic And Antiproliferative Agents That Treat Overexpression Of Tyrosine Phosphatase; Genetic Engineering
  • Protein Tyrosine Phosphatase Ptp20 And Related Products And Methods
  • Gene Products Differentially Expressed In Cancerous Cells And Their Methods Of Use Ii
  • Ptp05 Or Ptp10 Polypeptide; Nucleic Acid Encoding The Peptide And Probe For Detecting The Nucleic Acid; Recombinant Cell; Treating Diseases Caused By Ptp Abnormality Like Cancer And Diabetes
  • Polynucleotides For Use In The Treatment And Diagnosis Of Cancer And Autoimmune Diseases
  • Megakaryocytic Protein Tyrosine Kinases
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/332272a0

    DOI

    http://dx.doi.org/10.1038/332272a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1037158467

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2450282


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Amino Acid Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Avian Sarcoma Viruses", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Base Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Brain", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cattle", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cloning, Molecular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA, Recombinant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA, Viral", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genes, Viral", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Immunosorbent Techniques", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Molecular Sequence Data", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Oncogenes", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phosphatidylinositol Diacylglycerol-Lyase", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phosphoric Diester Hydrolases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phosphotyrosine", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Protein-Tyrosine Kinases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sequence Homology, Nucleic Acid", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Type C Phospholipases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tyrosine", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "The Rockefeller University, 10021, New York, New York, USA", 
              "id": "http://www.grid.ac/institutes/grid.134907.8", 
              "name": [
                "The Rockefeller University, 10021, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mayer", 
            "givenName": "Bruce J.", 
            "id": "sg:person.01244537451.59", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244537451.59"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Rockefeller University, 10021, New York, New York, USA", 
              "id": "http://www.grid.ac/institutes/grid.134907.8", 
              "name": [
                "The Rockefeller University, 10021, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hamaguchi", 
            "givenName": "Michinari", 
            "id": "sg:person.01033146126.76", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033146126.76"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "The Rockefeller University, 10021, New York, New York, USA", 
              "id": "http://www.grid.ac/institutes/grid.134907.8", 
              "name": [
                "The Rockefeller University, 10021, New York, New York, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hanafusa", 
            "givenName": "Hidesaburo", 
            "id": "sg:person.0707012145.99", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707012145.99"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/332269a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024899426", 
              "https://doi.org/10.1038/332269a0"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1988-03", 
        "datePublishedReg": "1988-03-01", 
        "description": "Numerous oncogenes have been isolated from acutely transforming retroviruses. To date, the products of these viral oncogenes have been protein kinases, nuclear proteins, growth factors, or GTP-binding proteins1,2. We have cloned the previously uncharacterized avian sarcoma virus CT10 and sequenced its genome. This virus encodes a protein, p47gag-crk, that has blocks of sequence similarity to the amino-terminal, non-catalytic region of the non-receptor class of tyrosine kinases. In addition, the structure of p47gag-crk has striking similarity to a 180-amino acid region of bovine brain phospholipase C. Biochemical data suggest that p47gag-crk activates one or several endogenous tyrosine kinases.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/332272a0", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0028-0836", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6161", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "332"
          }
        ], 
        "keywords": [
          "P47gag-crk", 
          "avian sarcoma virus CT10", 
          "tyrosine kinase", 
          "viral oncogenes", 
          "non-catalytic region", 
          "endogenous tyrosine kinases", 
          "sequence similarity", 
          "numerous oncogenes", 
          "protein kinase", 
          "nuclear proteins", 
          "acid region", 
          "kinase", 
          "oncogene", 
          "biochemical data", 
          "structural similarity", 
          "growth factor", 
          "protein", 
          "genome", 
          "similarity", 
          "retroviruses", 
          "CT10", 
          "region", 
          "amino", 
          "virus", 
          "date", 
          "structure", 
          "factors", 
          "addition", 
          "products", 
          "class", 
          "data", 
          "block"
        ], 
        "name": "A novel viral oncogene with structural similarity to phospholipase C", 
        "pagination": "272-275", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1037158467"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/332272a0"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "2450282"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/332272a0", 
          "https://app.dimensions.ai/details/publication/pub.1037158467"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:28", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_195.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/332272a0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/332272a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/332272a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/332272a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/332272a0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    191 TRIPLES      21 PREDICATES      79 URIs      70 LITERALS      27 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/332272a0 schema:about N062c500ed2da48c7b6511a89a5480439
    2 N07e3aee929884717afb0168a46636e4b
    3 N24304fa320094715b02310248f93b6f1
    4 N277af4c826d44d6cbbe96d18992cee9f
    5 N29945782ab4b454cbb5c1efc60b9551f
    6 N2cf920b108ab4769a4aa14c126802163
    7 N2fc0cb37d128449fada3f6cfbb354592
    8 N331a0760c83c4d1f868978b7018edbf4
    9 N48e772a2f07d4288a453d6652ce8200a
    10 N502d4497e5654c5896bae9fcce6ee8f7
    11 N5bada89f3e9c4ba2a9c6d6e97ff0b5e7
    12 N79f372a8cbf04d23b14959b4a845fc85
    13 N901f15780da44321989c22dfdab03d92
    14 N978cb396dd994737bb545dc625071fb1
    15 N9c4e4feb135c4aa2ad607a4b398908b3
    16 Na2e74fc971b844b3a915de058c916f1f
    17 Nd0a1878940c348828741bda772606e43
    18 Ne081d34a4e7449839292a4f8d26a72f7
    19 Nf4b8a10a44094bb3a45b664bbccce02e
    20 Nf660b8d721344732887711e60e847e8f
    21 anzsrc-for:06
    22 anzsrc-for:0601
    23 schema:author Nc7da5604797b4ee382fd9040fb6dd887
    24 schema:citation sg:pub.10.1038/332269a0
    25 schema:datePublished 1988-03
    26 schema:datePublishedReg 1988-03-01
    27 schema:description Numerous oncogenes have been isolated from acutely transforming retroviruses. To date, the products of these viral oncogenes have been protein kinases, nuclear proteins, growth factors, or GTP-binding proteins1,2. We have cloned the previously uncharacterized avian sarcoma virus CT10 and sequenced its genome. This virus encodes a protein, p47gag-crk, that has blocks of sequence similarity to the amino-terminal, non-catalytic region of the non-receptor class of tyrosine kinases. In addition, the structure of p47gag-crk has striking similarity to a 180-amino acid region of bovine brain phospholipase C. Biochemical data suggest that p47gag-crk activates one or several endogenous tyrosine kinases.
    28 schema:genre article
    29 schema:isAccessibleForFree false
    30 schema:isPartOf N4f709e09652f4c66a66193d6d0edd13d
    31 N5710f4dcf17643329c400e739de4d851
    32 sg:journal.1018957
    33 schema:keywords CT10
    34 P47gag-crk
    35 acid region
    36 addition
    37 amino
    38 avian sarcoma virus CT10
    39 biochemical data
    40 block
    41 class
    42 data
    43 date
    44 endogenous tyrosine kinases
    45 factors
    46 genome
    47 growth factor
    48 kinase
    49 non-catalytic region
    50 nuclear proteins
    51 numerous oncogenes
    52 oncogene
    53 products
    54 protein
    55 protein kinase
    56 region
    57 retroviruses
    58 sequence similarity
    59 similarity
    60 structural similarity
    61 structure
    62 tyrosine kinase
    63 viral oncogenes
    64 virus
    65 schema:name A novel viral oncogene with structural similarity to phospholipase C
    66 schema:pagination 272-275
    67 schema:productId N561c7a13f175463fba6ad8a6e14dae1d
    68 N96dba3bf01e64d74b7c10be1e30f82a9
    69 Nd31bea1de46c4d5086946bce81ec44ed
    70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037158467
    71 https://doi.org/10.1038/332272a0
    72 schema:sdDatePublished 2022-10-01T06:28
    73 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    74 schema:sdPublisher Na08940f55583476e86bc42974ec939c5
    75 schema:url https://doi.org/10.1038/332272a0
    76 sgo:license sg:explorer/license/
    77 sgo:sdDataset articles
    78 rdf:type schema:ScholarlyArticle
    79 N062c500ed2da48c7b6511a89a5480439 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    80 schema:name Tyrosine
    81 rdf:type schema:DefinedTerm
    82 N07e3aee929884717afb0168a46636e4b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    83 schema:name Molecular Sequence Data
    84 rdf:type schema:DefinedTerm
    85 N24304fa320094715b02310248f93b6f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name Cloning, Molecular
    87 rdf:type schema:DefinedTerm
    88 N277af4c826d44d6cbbe96d18992cee9f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    89 schema:name DNA, Recombinant
    90 rdf:type schema:DefinedTerm
    91 N29945782ab4b454cbb5c1efc60b9551f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    92 schema:name Animals
    93 rdf:type schema:DefinedTerm
    94 N2cf920b108ab4769a4aa14c126802163 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    95 schema:name Oncogenes
    96 rdf:type schema:DefinedTerm
    97 N2fc0cb37d128449fada3f6cfbb354592 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    98 schema:name Base Sequence
    99 rdf:type schema:DefinedTerm
    100 N331a0760c83c4d1f868978b7018edbf4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    101 schema:name Phosphotyrosine
    102 rdf:type schema:DefinedTerm
    103 N48e772a2f07d4288a453d6652ce8200a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    104 schema:name Phosphoric Diester Hydrolases
    105 rdf:type schema:DefinedTerm
    106 N4f709e09652f4c66a66193d6d0edd13d schema:issueNumber 6161
    107 rdf:type schema:PublicationIssue
    108 N502d4497e5654c5896bae9fcce6ee8f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    109 schema:name Amino Acid Sequence
    110 rdf:type schema:DefinedTerm
    111 N561c7a13f175463fba6ad8a6e14dae1d schema:name dimensions_id
    112 schema:value pub.1037158467
    113 rdf:type schema:PropertyValue
    114 N5710f4dcf17643329c400e739de4d851 schema:volumeNumber 332
    115 rdf:type schema:PublicationVolume
    116 N5bada89f3e9c4ba2a9c6d6e97ff0b5e7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    117 schema:name Genes, Viral
    118 rdf:type schema:DefinedTerm
    119 N73a73fececfb4d9ca3dc485b06e36c60 rdf:first sg:person.0707012145.99
    120 rdf:rest rdf:nil
    121 N7991cabfb97c469dadfa98bd2bfafdd8 rdf:first sg:person.01033146126.76
    122 rdf:rest N73a73fececfb4d9ca3dc485b06e36c60
    123 N79f372a8cbf04d23b14959b4a845fc85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    124 schema:name Immunosorbent Techniques
    125 rdf:type schema:DefinedTerm
    126 N901f15780da44321989c22dfdab03d92 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    127 schema:name Cattle
    128 rdf:type schema:DefinedTerm
    129 N96dba3bf01e64d74b7c10be1e30f82a9 schema:name doi
    130 schema:value 10.1038/332272a0
    131 rdf:type schema:PropertyValue
    132 N978cb396dd994737bb545dc625071fb1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    133 schema:name Type C Phospholipases
    134 rdf:type schema:DefinedTerm
    135 N9c4e4feb135c4aa2ad607a4b398908b3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    136 schema:name Sequence Homology, Nucleic Acid
    137 rdf:type schema:DefinedTerm
    138 Na08940f55583476e86bc42974ec939c5 schema:name Springer Nature - SN SciGraph project
    139 rdf:type schema:Organization
    140 Na2e74fc971b844b3a915de058c916f1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Protein-Tyrosine Kinases
    142 rdf:type schema:DefinedTerm
    143 Nc7da5604797b4ee382fd9040fb6dd887 rdf:first sg:person.01244537451.59
    144 rdf:rest N7991cabfb97c469dadfa98bd2bfafdd8
    145 Nd0a1878940c348828741bda772606e43 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    146 schema:name DNA, Viral
    147 rdf:type schema:DefinedTerm
    148 Nd31bea1de46c4d5086946bce81ec44ed schema:name pubmed_id
    149 schema:value 2450282
    150 rdf:type schema:PropertyValue
    151 Ne081d34a4e7449839292a4f8d26a72f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    152 schema:name Avian Sarcoma Viruses
    153 rdf:type schema:DefinedTerm
    154 Nf4b8a10a44094bb3a45b664bbccce02e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    155 schema:name Brain
    156 rdf:type schema:DefinedTerm
    157 Nf660b8d721344732887711e60e847e8f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    158 schema:name Phosphatidylinositol Diacylglycerol-Lyase
    159 rdf:type schema:DefinedTerm
    160 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    161 schema:name Biological Sciences
    162 rdf:type schema:DefinedTerm
    163 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    164 schema:name Biochemistry and Cell Biology
    165 rdf:type schema:DefinedTerm
    166 sg:journal.1018957 schema:issn 0028-0836
    167 1476-4687
    168 schema:name Nature
    169 schema:publisher Springer Nature
    170 rdf:type schema:Periodical
    171 sg:person.01033146126.76 schema:affiliation grid-institutes:grid.134907.8
    172 schema:familyName Hamaguchi
    173 schema:givenName Michinari
    174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033146126.76
    175 rdf:type schema:Person
    176 sg:person.01244537451.59 schema:affiliation grid-institutes:grid.134907.8
    177 schema:familyName Mayer
    178 schema:givenName Bruce J.
    179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01244537451.59
    180 rdf:type schema:Person
    181 sg:person.0707012145.99 schema:affiliation grid-institutes:grid.134907.8
    182 schema:familyName Hanafusa
    183 schema:givenName Hidesaburo
    184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707012145.99
    185 rdf:type schema:Person
    186 sg:pub.10.1038/332269a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024899426
    187 https://doi.org/10.1038/332269a0
    188 rdf:type schema:CreativeWork
    189 grid-institutes:grid.134907.8 schema:alternateName The Rockefeller University, 10021, New York, New York, USA
    190 schema:name The Rockefeller University, 10021, New York, New York, USA
    191 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...