The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptors View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1987-07

AUTHORS

Gabriele Grenningloh, Axel Rienitz, Bertram Schmitt, Christoph Methfessel, Monika Zensen, Konrad Beyreuther, Eckart D. Gundelfinger, Heinrich Betz

ABSTRACT

We have cloned and sequenced cDNAs of the strychnine-binding subunit of the rat glycine receptor, a neurotransmitter-gated chloride channel protein of the CNS. The deduced polypeptide shows significant structural and amino-acid sequence homology with nicotinic acetylcholine receptor proteins, indicating that there is a family of genes encoding neurotransmitter-gated ion channels.

PAGES

215-220

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/328215a0

DOI

http://dx.doi.org/10.1038/328215a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034973265

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3037383


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