The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1987-01

AUTHORS

Diomedes E. Logothetis, Yoshihisa Kurachi, Jonas Galper, Eva J. Neer, David E. Clapham

ABSTRACT

Subunits ofguanine nucleotide regulatory proteins purified from bovine cerebral cortex were used to perfuse the intracellular surface of excised patches of chick embryonic atrial cells. Single-channel current measurements unexpectedly indicate that the βγ, and not the a subunits, are responsible for activating the muscarinic-gated potassium channel.

PAGES

321-326

References to SciGraph publications

Journal

TITLE

Nature

ISSUE

6102

VOLUME

325

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/325321a0

DOI

http://dx.doi.org/10.1038/325321a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042146376

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2433589


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