The c-erb-A protein is a high-affinity receptor for thyroid hormone View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1986-12

AUTHORS

Jan Sap, Alberto Muñoz, Klaus Damm, Yves Goldberg, Jacques Ghysdael, Achim Leutz, Hartmut Beug, Björn Vennström

ABSTRACT

Hormone binding and localization of the c-erb-A protein suggest that it is a receptor for thyroid hormone, a nuclear protein that binds to DNA and activates transcription. In contrast, the product of the viral oncogene v-erb-A is defective in binding the hormone but is still located in the nucleus.

PAGES

635-640

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/324635a0

DOI

http://dx.doi.org/10.1038/324635a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000355348

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2879242


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