Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1986-10

AUTHORS

Tai Kubo, Kazuhiko Fukuda, Atsushi Mikami, Akito Maeda, Hideo Takahashi, Masayoshi Mishina, Tatsuya Haga, Kazuko Haga, Arata Ichiyama, Kenji Kangawa, Masayasu Kojima, Hisayuki Matsuo, Tadaaki Hirose, Shosaku Numa

ABSTRACT

Cloning and sequence analysis of DNA complementary to porcine cerebral messenger RNA encoding the muscarinic acetylcholine receptor predict the complete amino-acid sequence of this protein. Expression of the complementary DNA produces functional muscarinic receptor in Xenopus oocytes. The muscarinic receptor is homologous with the β-adrenergic receptor and rhodopsin in both amino-acid sequence and suggested transmembrane topography. More... »

PAGES

411-416

Journal

TITLE

Nature

ISSUE

6087

VOLUME

323

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/323411a0

    DOI

    http://dx.doi.org/10.1038/323411a0

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/3762692


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