Specific interaction between the p53 cellular tumour antigen and major heat shock proteins View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1986-03

AUTHORS

Orit Pinhasi-Kimhi, Dan Michalovitz, Avri Ben-Zeev, Moshe Oren

ABSTRACT

The protein p53 is capable of participating in neoplastic transformation1–3 and can form specific complexes with the large-T antigen of simian virus 40 (SV40)4–6. This interaction probably results in the stabilization of p53 (refs 7, 8) and may contribute to SV40-mediated transformation9,10. Several non-SV40-trans-formed cells also exhibit a stabilized p53 which is present in elevated levels11–13. Recently, this stabilization was shown to coincide with the ability to precipitate a polypeptide (p68) of relative molecular mass (Mr) 68,000–70,000 by anti-p53 monoclonal antibodies13–15. We now report that this co-precipitation indeed represents a specific complex between the two proteins; the complex sediments on a sucrose gradient as a relatively broad peak of 10–14S and can be dissociated in vitro. Furthermore, p68 is the HSP70 heat shock protein cognate, found in elevated levels in a p53-overproducing cell line. On heat-shock treatment of such overproduces, p53 also forms a complex with the related highly inducible HSP68. More... »

PAGES

182-185

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/320182a0

DOI

http://dx.doi.org/10.1038/320182a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1020926485

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3513022


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Cycle", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Heat-Shock Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Isoelectric Point", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Weight", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasm Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Phosphoproteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Binding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Rats", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Suppressor Protein p53", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel", 
          "id": "http://www.grid.ac/institutes/grid.13992.30", 
          "name": [
            "Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pinhasi-Kimhi", 
        "givenName": "Orit", 
        "id": "sg:person.01225172351.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225172351.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel", 
          "id": "http://www.grid.ac/institutes/grid.13992.30", 
          "name": [
            "Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Michalovitz", 
        "givenName": "Dan", 
        "id": "sg:person.01172740447.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172740447.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Genetics, Weizmann Institute of Science, 76100, Rehovot, Israel", 
          "id": "http://www.grid.ac/institutes/grid.13992.30", 
          "name": [
            "Department of Genetics, Weizmann Institute of Science, 76100, Rehovot, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ben-Zeev", 
        "givenName": "Avri", 
        "id": "sg:person.077756236.49", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.077756236.49"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel", 
          "id": "http://www.grid.ac/institutes/grid.13992.30", 
          "name": [
            "Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Oren", 
        "givenName": "Moshe", 
        "id": "sg:person.0654632765.36", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654632765.36"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/312649a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045403650", 
          "https://doi.org/10.1038/312649a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/312646a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004629945", 
          "https://doi.org/10.1038/312646a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/312651a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047086040", 
          "https://doi.org/10.1038/312651a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/316158a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031701159", 
          "https://doi.org/10.1038/316158a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1986-03", 
    "datePublishedReg": "1986-03-01", 
    "description": "The protein p53 is capable of participating in neoplastic transformation1\u20133 and can form specific complexes with the large-T antigen of simian virus 40 (SV40)4\u20136. This interaction probably results in the stabilization of p53 (refs 7, 8) and may contribute to SV40-mediated transformation9,10. Several non-SV40-trans-formed cells also exhibit a stabilized p53 which is present in elevated levels11\u201313. Recently, this stabilization was shown to coincide with the ability to precipitate a polypeptide (p68) of relative molecular mass (Mr) 68,000\u201370,000 by anti-p53 monoclonal antibodies13\u201315. We now report that this co-precipitation indeed represents a specific complex between the two proteins; the complex sediments on a sucrose gradient as a relatively broad peak of 10\u201314S and can be dissociated in vitro. Furthermore, p68 is the HSP70 heat shock protein cognate, found in elevated levels in a p53-overproducing cell line. On heat-shock treatment of such overproduces, p53 also forms a complex with the related highly inducible HSP68.", 
    "genre": "article", 
    "id": "sg:pub.10.1038/320182a0", 
    "inLanguage": "en", 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2468493", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0028-0836", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "publisher": "Springer Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6058", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "320"
      }
    ], 
    "keywords": [
      "tumor antigens", 
      "heat shock proteins", 
      "elevated levels", 
      "simian virus 40", 
      "cell lines", 
      "major heat shock proteins", 
      "antigen", 
      "p53", 
      "stabilization of p53", 
      "shock proteins", 
      "heat-shock treatment", 
      "protein p53", 
      "cellular tumor antigen", 
      "p53 cellular tumor antigen", 
      "protein cognate", 
      "inducible hsp68", 
      "treatment", 
      "protein", 
      "cells", 
      "sucrose gradients", 
      "relative molecular mass", 
      "levels", 
      "p68", 
      "stabilization", 
      "mass", 
      "polypeptide", 
      "ability", 
      "hsp68", 
      "lines", 
      "overproduce", 
      "molecular mass", 
      "specific complex", 
      "specific interactions", 
      "interaction", 
      "complexes", 
      "complex sediments", 
      "peak", 
      "cognates", 
      "gradient", 
      "broad peak", 
      "transformation1", 
      "sediments", 
      "neoplastic transformation1", 
      "virus 40", 
      "SV40-mediated", 
      "elevated levels11", 
      "levels11", 
      "anti-p53 monoclonal antibodies13", 
      "monoclonal antibodies13", 
      "antibodies13", 
      "HSP70 heat shock protein cognate", 
      "heat shock protein cognate", 
      "shock protein cognate", 
      "p53-overproducing cell line", 
      "such overproduces"
    ], 
    "name": "Specific interaction between the p53 cellular tumour antigen and major heat shock proteins", 
    "pagination": "182-185", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1020926485"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/320182a0"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "3513022"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/320182a0", 
      "https://app.dimensions.ai/details/publication/pub.1020926485"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2021-12-01T19:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20211201/entities/gbq_results/article/article_199.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "https://doi.org/10.1038/320182a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/320182a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/320182a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/320182a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/320182a0'


 

This table displays all metadata directly associated to this object as RDF triples.

202 TRIPLES      22 PREDICATES      97 URIs      85 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/320182a0 schema:about N3c42fdc4f05d4b438fb80d36e73349b2
2 N3f22a2e232114c26b367a12b9ce9f091
3 N649c5aee1ef643068d5fff55f1a8388b
4 N8606d2b4e4b4400686367a5f6a58150f
5 Na426ba486cd44720916c25c5106b44d6
6 Nc1b30989deee4a06bc746e13f434bcf9
7 Ncf42ca16d189449daf63ee2ab51e8c7d
8 Nd21d413498aa446792df4078f584cab8
9 Ndbfbe8ee04e246a1a1c86dfc584b6bf0
10 Nec596b2abfcb4ba581b5dd91a6650437
11 Nfce2818bbdd944b888c3d594c2259200
12 anzsrc-for:06
13 anzsrc-for:0601
14 schema:author N6202044115534c9caf84a2eb07b48036
15 schema:citation sg:pub.10.1038/312646a0
16 sg:pub.10.1038/312649a0
17 sg:pub.10.1038/312651a0
18 sg:pub.10.1038/316158a0
19 schema:datePublished 1986-03
20 schema:datePublishedReg 1986-03-01
21 schema:description The protein p53 is capable of participating in neoplastic transformation1–3 and can form specific complexes with the large-T antigen of simian virus 40 (SV40)4–6. This interaction probably results in the stabilization of p53 (refs 7, 8) and may contribute to SV40-mediated transformation9,10. Several non-SV40-trans-formed cells also exhibit a stabilized p53 which is present in elevated levels11–13. Recently, this stabilization was shown to coincide with the ability to precipitate a polypeptide (p68) of relative molecular mass (Mr) 68,000–70,000 by anti-p53 monoclonal antibodies13–15. We now report that this co-precipitation indeed represents a specific complex between the two proteins; the complex sediments on a sucrose gradient as a relatively broad peak of 10–14S and can be dissociated in vitro. Furthermore, p68 is the HSP70 heat shock protein cognate, found in elevated levels in a p53-overproducing cell line. On heat-shock treatment of such overproduces, p53 also forms a complex with the related highly inducible HSP68.
22 schema:genre article
23 schema:inLanguage en
24 schema:isAccessibleForFree false
25 schema:isPartOf N4560481142ee4a82a4331e77fa50f265
26 N6a9a5d85cff245ff9150fb40d19fa648
27 sg:journal.1018957
28 schema:keywords HSP70 heat shock protein cognate
29 SV40-mediated
30 ability
31 anti-p53 monoclonal antibodies13
32 antibodies13
33 antigen
34 broad peak
35 cell lines
36 cells
37 cellular tumor antigen
38 cognates
39 complex sediments
40 complexes
41 elevated levels
42 elevated levels11
43 gradient
44 heat shock protein cognate
45 heat shock proteins
46 heat-shock treatment
47 hsp68
48 inducible hsp68
49 interaction
50 levels
51 levels11
52 lines
53 major heat shock proteins
54 mass
55 molecular mass
56 monoclonal antibodies13
57 neoplastic transformation1
58 overproduce
59 p53
60 p53 cellular tumor antigen
61 p53-overproducing cell line
62 p68
63 peak
64 polypeptide
65 protein
66 protein cognate
67 protein p53
68 relative molecular mass
69 sediments
70 shock protein cognate
71 shock proteins
72 simian virus 40
73 specific complex
74 specific interactions
75 stabilization
76 stabilization of p53
77 such overproduces
78 sucrose gradients
79 transformation1
80 treatment
81 tumor antigens
82 virus 40
83 schema:name Specific interaction between the p53 cellular tumour antigen and major heat shock proteins
84 schema:pagination 182-185
85 schema:productId N272d2003fbd4462d84ab62043a8bc1a0
86 N6c75f9c77d894b0eb63b357293637559
87 N9cbb50cfda9a48a7af9d56172e5056c1
88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020926485
89 https://doi.org/10.1038/320182a0
90 schema:sdDatePublished 2021-12-01T19:05
91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
92 schema:sdPublisher Nd079c349a72b45129165cc67ccfeffb2
93 schema:url https://doi.org/10.1038/320182a0
94 sgo:license sg:explorer/license/
95 sgo:sdDataset articles
96 rdf:type schema:ScholarlyArticle
97 N13862ec959df4cb788fab2282fb972f2 rdf:first sg:person.01172740447.46
98 rdf:rest Nd3c0accfee9a467c8b648d893fc3fc97
99 N272d2003fbd4462d84ab62043a8bc1a0 schema:name pubmed_id
100 schema:value 3513022
101 rdf:type schema:PropertyValue
102 N3c42fdc4f05d4b438fb80d36e73349b2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Neoplasm Proteins
104 rdf:type schema:DefinedTerm
105 N3f22a2e232114c26b367a12b9ce9f091 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Phosphoproteins
107 rdf:type schema:DefinedTerm
108 N4560481142ee4a82a4331e77fa50f265 schema:issueNumber 6058
109 rdf:type schema:PublicationIssue
110 N5e39a95812874d03ae4c6da6d035a735 rdf:first sg:person.0654632765.36
111 rdf:rest rdf:nil
112 N6202044115534c9caf84a2eb07b48036 rdf:first sg:person.01225172351.25
113 rdf:rest N13862ec959df4cb788fab2282fb972f2
114 N649c5aee1ef643068d5fff55f1a8388b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Isoelectric Point
116 rdf:type schema:DefinedTerm
117 N6a9a5d85cff245ff9150fb40d19fa648 schema:volumeNumber 320
118 rdf:type schema:PublicationVolume
119 N6c75f9c77d894b0eb63b357293637559 schema:name dimensions_id
120 schema:value pub.1020926485
121 rdf:type schema:PropertyValue
122 N8606d2b4e4b4400686367a5f6a58150f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Cells, Cultured
124 rdf:type schema:DefinedTerm
125 N9cbb50cfda9a48a7af9d56172e5056c1 schema:name doi
126 schema:value 10.1038/320182a0
127 rdf:type schema:PropertyValue
128 Na426ba486cd44720916c25c5106b44d6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name Molecular Weight
130 rdf:type schema:DefinedTerm
131 Nc1b30989deee4a06bc746e13f434bcf9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
132 schema:name Heat-Shock Proteins
133 rdf:type schema:DefinedTerm
134 Ncf42ca16d189449daf63ee2ab51e8c7d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
135 schema:name Protein Binding
136 rdf:type schema:DefinedTerm
137 Nd079c349a72b45129165cc67ccfeffb2 schema:name Springer Nature - SN SciGraph project
138 rdf:type schema:Organization
139 Nd21d413498aa446792df4078f584cab8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
140 schema:name Cell Cycle
141 rdf:type schema:DefinedTerm
142 Nd3c0accfee9a467c8b648d893fc3fc97 rdf:first sg:person.077756236.49
143 rdf:rest N5e39a95812874d03ae4c6da6d035a735
144 Ndbfbe8ee04e246a1a1c86dfc584b6bf0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Tumor Suppressor Protein p53
146 rdf:type schema:DefinedTerm
147 Nec596b2abfcb4ba581b5dd91a6650437 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Animals
149 rdf:type schema:DefinedTerm
150 Nfce2818bbdd944b888c3d594c2259200 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
151 schema:name Rats
152 rdf:type schema:DefinedTerm
153 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
154 schema:name Biological Sciences
155 rdf:type schema:DefinedTerm
156 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
157 schema:name Biochemistry and Cell Biology
158 rdf:type schema:DefinedTerm
159 sg:grant.2468493 http://pending.schema.org/fundedItem sg:pub.10.1038/320182a0
160 rdf:type schema:MonetaryGrant
161 sg:journal.1018957 schema:issn 0028-0836
162 1476-4687
163 schema:name Nature
164 schema:publisher Springer Nature
165 rdf:type schema:Periodical
166 sg:person.01172740447.46 schema:affiliation grid-institutes:grid.13992.30
167 schema:familyName Michalovitz
168 schema:givenName Dan
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172740447.46
170 rdf:type schema:Person
171 sg:person.01225172351.25 schema:affiliation grid-institutes:grid.13992.30
172 schema:familyName Pinhasi-Kimhi
173 schema:givenName Orit
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01225172351.25
175 rdf:type schema:Person
176 sg:person.0654632765.36 schema:affiliation grid-institutes:grid.13992.30
177 schema:familyName Oren
178 schema:givenName Moshe
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0654632765.36
180 rdf:type schema:Person
181 sg:person.077756236.49 schema:affiliation grid-institutes:grid.13992.30
182 schema:familyName Ben-Zeev
183 schema:givenName Avri
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.077756236.49
185 rdf:type schema:Person
186 sg:pub.10.1038/312646a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004629945
187 https://doi.org/10.1038/312646a0
188 rdf:type schema:CreativeWork
189 sg:pub.10.1038/312649a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045403650
190 https://doi.org/10.1038/312649a0
191 rdf:type schema:CreativeWork
192 sg:pub.10.1038/312651a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047086040
193 https://doi.org/10.1038/312651a0
194 rdf:type schema:CreativeWork
195 sg:pub.10.1038/316158a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031701159
196 https://doi.org/10.1038/316158a0
197 rdf:type schema:CreativeWork
198 grid-institutes:grid.13992.30 schema:alternateName Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel
199 Department of Genetics, Weizmann Institute of Science, 76100, Rehovot, Israel
200 schema:name Department of Chemical Immunology, Weizmann Institute of Science, 76100, Rehovot, Israel
201 Department of Genetics, Weizmann Institute of Science, 76100, Rehovot, Israel
202 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...