Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-09

AUTHORS

Oliver Smithies, Ronald G. Gregg, Sallie S. Boggs, Michael A. Koralewski, Raju S. Kucherlapati

ABSTRACT

A 'rescuable' plasmid containing globin gene sequences allowing recombination with homologous chromosomal sequences has enabled us to produce, score and clone mammalian cells with the plasmid integrated into the human beta-globin locus. The planned modification was achieved in about one per thousand transformed cells whether or not the target gene was expressed. More... »

PAGES

230-234

Journal

TITLE

Nature

ISSUE

6034

VOLUME

317

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/317230a0

    DOI

    http://dx.doi.org/10.1038/317230a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1005647127

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/2995814


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    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/317230a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/317230a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/317230a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/317230a0'


     

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