Structural analysis of murine genes containing homoeo box sequences and their expression in embryonal carcinoma cells View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-04

AUTHORS

Anamaris M. Colberg-Poley, Stephan D. Voss, Kamal Chowdhury, Peter Gruss

ABSTRACT

The presence of homoeo box sequences in the genomes of vertebrates has suggested that these metazoans possess the equivalent of the homoeotic genes that have a key role in regulating the development of the fruitfly Drosophila melanogaster. We report here that a novel murine homoeo box-containing gene is expressed in embryonal carcinoma stem cells. Transcripts of the sequences that flank the homoeo box of this gene are found in these cells before and after induced differentiation, whereas a specific transcript that seems to contain the homoeo sequence is only present after differentiation. More... »

PAGES

713

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/314713a0

DOI

http://dx.doi.org/10.1038/314713a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019840622

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2986010


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