Molecular cloning of Ancient Egyptian mummy DNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-04

AUTHORS

Svante Pääbo

ABSTRACT

Artificial mummification was practised in Egypt from approximately 2600 BC until the fourth century AD. Because of the dry Egyptian climate, however, there are also many natural mummies preserved from earlier as well as later times. To elucidate whether this unique source of ancient human remains can be used for molecular genetic analyses, 23 mummies were investigated for DNA content. One 2,400-yr-old mummy of a child was found to contain DNA that could be molecularly cloned in a plasmid vector. I report here that one such clone contains two members of the Alu family of human repetitive DNA sequences, as detected by DNA hybridizations and nucleotide sequencing. These analyses show that substantial pieces of mummy DNA (3.4 kilobases) can be cloned and that the DNA fragments seem to contain little or no modifications introduced postmortem. More... »

PAGES

644-645

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/314644a0

DOI

http://dx.doi.org/10.1038/314644a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1044179528

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3990798


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