Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-04

AUTHORS

Anne Chomyn, Paolo Mariottini, Michael W. J. Cleeter, C. Ian Ragan, Akemi Matsuno-Yagi, Youssef Hatefi, Russell F. Doolittle, Giuseppe Attardi

ABSTRACT

The products of six unidentified reading frames of human mitochondrial DNA are precipitated from a mitochondrial lysate by antibodies against highly purified native beef heart NADH-ubiquinone oxidoreductase (complex I). These products are enriched greatly in a human submitochondrial fraction enriched in NADH-Q1 and NADH-K3Fe(CN)6 oxidoreductase activities. We conclude that the six reading frames encode components of the respiratory-chain NADH dehydrogenase. More... »

PAGES

592-597

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/314592a0

DOI

http://dx.doi.org/10.1038/314592a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029259530

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3921850


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