Hypervariable ‘minisatellite’ regions in human DNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-03

AUTHORS

Alec J. Jeffreys, Victoria Wilson, Swee Lay Thein

ABSTRACT

The human genome contains many dispersed tandem-repetitive ‘minisatellite’ regions detected via a shared 10–15-base pair ‘core’ sequence similar to the generalized recombination signal (χ) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite. A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis. More... »

PAGES

67-73

Journal

TITLE

Nature

ISSUE

6006

VOLUME

314

Related Patents

  • Y Chromosome Specific Nucleic Acid Probe And Method For Determining The Y Chromosome In Situ
  • Polymorphic Dna Markers In Bovidae
  • Thermal Reaction Device And Method For Using The Same
  • Methods And Devices For Electronic And Magnetic Sensing Of The Contents Of Microfluidic Flow Channels
  • Microfluidic Rotary Flow Reactor Matrix
  • Length Polymorphisms In (Dc-Da)N.(Dg-Dt)N Sequences And Method Of Using The Same
  • Methods For Detecting And Sorting Polynucleotides Based On Size
  • Microfluidic Device And Methods Of Using Same
  • Microfluidic Device And Methods Of Using Same
  • Automatic Genotype Determination
  • Microfluidic Device And Methods Of Using Same
  • Methods And Devices For Electronic Sensing
  • Microfluidic Device And Methods Of Using Same
  • Hybridation Probe For Detection Of Polymorphic Nucleotide Sequences Contained In A Human Or Animal Dna Sample, Method For Detecting Polymorphic Dna Sequences Using Such A Probe, Its Biological Applications
  • Hybridization Probe For The Detection Of Polymorphic Nucleotide Sequences
  • Polynucleotide Sequence And Its Applications As Molecular Probe For Establishing Genetic Fingerprints Of Various Plant And Animal Species
  • Materials And Methods For Indentifying And Analyzing Intermediate Tandem Repeat Dna Markers
  • Polynucleotide Probes
  • Polynucleotide Probes For Horses
  • Multiplexed Method For The Identification And Quantitation Of Minor Alleles And Polymorphisms
  • Microfabricated Cell Sorter
  • Synthetic Dna Probes
  • Detection Of Residual Host Cell Dna By Pcr
  • Recirculating Fluidic Network And Methods For Using The Same
  • Multiplex Amplification Of Short Tandem Repeat Loci
  • Methods And Devices For Electronic Sensing
  • Microfluidic Device With Reaction Sites Configured For Blind Filling
  • Microfluidic Particle-Analysis Systems
  • Microfluidic Particle-Analysis Systems
  • Genetic Diagnosis Of Torsion Dystonia
  • Recirculating Fluidic Network And Methods For Using The Same
  • Materials And Methods For Identifying And Analyzing Intermediate Tandem Repeat Dna Markers
  • Microfluidic Nucleic Acid Analysis
  • Apparatus For Preparing Cdna Libraries From Single Cells
  • Process For Detection Of New Polymorphic Loci In A Dna Sequence, Nucleotide Sequences Forming Hybridization Probes And Their Applications
  • Linkage Analysis Of Genes With Diseases Using Difference Spectrum Analysis
  • Thermal Reaction Device And Method For Using The Same
  • Thermal Reaction Device And Method For Using The Same
  • Generalized Method For Assessment Of Colorectal Carcinoma
  • Materials And Methods For Achieving Differential Lysis Of Mixtures With The Aid Of Alkaline Lysis And Pressure Cycling Technology (Pct)
  • Microfluidic Devices And Methods Of Using Same
  • Microfluidic Nucleic Acid Analysis
  • Hybridization Probe For The Detection Of Polymorphic Nucleotide Sequences
  • Five Highly Informative Microsatellite Repeat Polymorphic Dna Markers
  • Method Of Characterizing Genomic Dna By Reference To A Genetic Variable
  • Three Highly Informative Microsatellite Repeat Polymorphic Dna Markers
  • Compositions And Methods For Analyzing Genomic Variation
  • A Method For The Simultaneous Determination Of Dna Sequence Variations At A Large Number Of Sites, And A Kit Therefor
  • Nucleic Acid Amplification Using Microfluidic Devices
  • Recirculating Fluidic Network And Methods For Using The Same
  • Microfluidic Devices And Methods Of Using Same
  • Thermal Reaction Device And Method For Using The Same
  • Generalized Method For Cancer Assessment
  • Thermal Reaction Device And Method For Using The Same
  • Integrated Active Flux Microfluidic Devices And Methods
  • Microfluidic Device And Methods Of Using Same
  • Integrated Active Flux Microfluidic Devices And Methods
  • Microfluidic Particle-Analysis Systems
  • Infrared Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis Of Macromolecules
  • Microfluidic Particle-Analysis Systems
  • Fragmentation-Based Methods And Systems For Sequence Variation Detection And Discovery
  • Highly Informative Microsatellite Repeat Polymorphic Dna Markers Twenty-[Seven]Six
  • Thermal Reaction Device And Method For Using The Same
  • Thermal Reaction Device And Method For Using The Same
  • Performance
  • Microfabricated Structure Having Parallel And Orthogonal Flow Channels Controlled By Row And Column Multiplexors
  • Nucleic Acid Amplification Using Microfluidic Devices
  • Integrated Active Flux Microfluidic Devices And Methods
  • Hypervariable Restriction Fragment Length Polymorphisms Within The Abr Gene
  • Eleven Highly Informative Microsatelite Repeat Polymorphic Dna Markers
  • Compositions And Methods Useful For Genetic Analysis
  • Multiplex Amplification Of Short Tandem Repeat Loci
  • Improvements In Genetic Probes
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/314067a0

    DOI

    http://dx.doi.org/10.1038/314067a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1047897100

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/3856104


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Alleles", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Base Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA, Satellite", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Engineering", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Variation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Heterozygote", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mutation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Nucleic Acid Hybridization", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Pedigree", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Polymorphism, Genetic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Recombination, Genetic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Repetitive Sequences, Nucleic Acid", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Department of Genetics, University of Leicester, University Road, LE1 7RH, Leicester, UK", 
              "id": "http://www.grid.ac/institutes/grid.9918.9", 
              "name": [
                "Department of Genetics, University of Leicester, University Road, LE1 7RH, Leicester, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jeffreys", 
            "givenName": "Alec J.", 
            "id": "sg:person.01010325224.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010325224.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Genetics, University of Leicester, University Road, LE1 7RH, Leicester, UK", 
              "id": "http://www.grid.ac/institutes/grid.9918.9", 
              "name": [
                "Department of Genetics, University of Leicester, University Road, LE1 7RH, Leicester, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wilson", 
            "givenName": "Victoria", 
            "id": "sg:person.01163631601.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163631601.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "MRC Molecular Haematology Unit, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, OX3 9DU, Headington, Oxford, UK", 
              "id": "http://www.grid.ac/institutes/grid.8348.7", 
              "name": [
                "MRC Molecular Haematology Unit, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, OX3 9DU, Headington, Oxford, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Thein", 
            "givenName": "Swee Lay", 
            "id": "sg:person.01274511101.91", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274511101.91"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/302033a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031650611", 
              "https://doi.org/10.1038/302033a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/295031a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017331230", 
              "https://doi.org/10.1038/295031a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/309176a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037654366", 
              "https://doi.org/10.1038/309176a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/309170a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013017501", 
              "https://doi.org/10.1038/309170a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/300069a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034929435", 
              "https://doi.org/10.1038/300069a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/305779a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049589192", 
              "https://doi.org/10.1038/305779a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00275182", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043397192", 
              "https://doi.org/10.1007/bf00275182"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/309172a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006555130", 
              "https://doi.org/10.1038/309172a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/299111a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030897036", 
              "https://doi.org/10.1038/299111a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/306234a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008727690", 
              "https://doi.org/10.1038/306234a0"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1985-03", 
        "datePublishedReg": "1985-03-01", 
        "description": "The human genome contains many dispersed tandem-repetitive \u2018minisatellite\u2019 regions detected via a shared 10\u201315-base pair \u2018core\u2019 sequence similar to the generalized recombination signal (\u03c7) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite. A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA \u2018fingerprint\u2019 of general use in human genetic analysis.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/314067a0", 
        "inLanguage": "en", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0028-0836", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "6006", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "314"
          }
        ], 
        "keywords": [
          "human genetic analysis", 
          "repeat copy number", 
          "variable loci", 
          "human genome", 
          "recombination signals", 
          "allelic variation", 
          "genetic analysis", 
          "Escherichia coli", 
          "core sequence", 
          "minisatellites", 
          "human DNA", 
          "copy number", 
          "individual-specific DNA", 
          "DNA", 
          "sequence", 
          "genome", 
          "loci", 
          "coli", 
          "region", 
          "probe", 
          "fingerprints", 
          "variation", 
          "pairs", 
          "signals", 
          "general use", 
          "analysis", 
          "number", 
          "core", 
          "use", 
          "generalized recombination signal"
        ], 
        "name": "Hypervariable \u2018minisatellite\u2019 regions in human DNA", 
        "pagination": "67-73", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1047897100"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/314067a0"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "3856104"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/314067a0", 
          "https://app.dimensions.ai/details/publication/pub.1047897100"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2021-11-01T17:57", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20211101/entities/gbq_results/article/article_195.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/314067a0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/314067a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/314067a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/314067a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/314067a0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    201 TRIPLES      22 PREDICATES      80 URIs      62 LITERALS      20 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/314067a0 schema:about N08f6e67a51cc45209d1b570189a4efc6
    2 N12d28df761d948a4be7e77f124f13862
    3 N2108e63f3f8349ecbf9807bd86e9c0b7
    4 N3ca9fe215a2640a7bd75e772a63c0a85
    5 N4091585826c94f5c8b3cf4f14a131565
    6 N54897f8ac9f743218b4b13156f984326
    7 N7ca170634a93456cb91b239dcf33cde1
    8 Na5201d2dff71480ebed0e8b0d25a4c6b
    9 Nb074bfe00d8041e4aab822569710db30
    10 Nb99aa42503374efbb0155a03618435e1
    11 Nd30c24a924014a0cb3831c7af796524f
    12 Nfe8a834f892847bca2a1a18fb64358c4
    13 Nff8b159a591840baac5a639e3f2435d2
    14 anzsrc-for:06
    15 anzsrc-for:0604
    16 schema:author N5bdddaf4967c478c8b6bc871415faf84
    17 schema:citation sg:pub.10.1007/bf00275182
    18 sg:pub.10.1038/295031a0
    19 sg:pub.10.1038/299111a0
    20 sg:pub.10.1038/300069a0
    21 sg:pub.10.1038/302033a0
    22 sg:pub.10.1038/305779a0
    23 sg:pub.10.1038/306234a0
    24 sg:pub.10.1038/309170a0
    25 sg:pub.10.1038/309172a0
    26 sg:pub.10.1038/309176a0
    27 schema:datePublished 1985-03
    28 schema:datePublishedReg 1985-03-01
    29 schema:description The human genome contains many dispersed tandem-repetitive ‘minisatellite’ regions detected via a shared 10–15-base pair ‘core’ sequence similar to the generalized recombination signal (χ) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite. A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA ‘fingerprint’ of general use in human genetic analysis.
    30 schema:genre article
    31 schema:inLanguage en
    32 schema:isAccessibleForFree false
    33 schema:isPartOf N1fb08511f23c4ce2b9311d7b27addd50
    34 Ne53d4326410c40f28e0cdcebf868b256
    35 sg:journal.1018957
    36 schema:keywords DNA
    37 Escherichia coli
    38 allelic variation
    39 analysis
    40 coli
    41 copy number
    42 core
    43 core sequence
    44 fingerprints
    45 general use
    46 generalized recombination signal
    47 genetic analysis
    48 genome
    49 human DNA
    50 human genetic analysis
    51 human genome
    52 individual-specific DNA
    53 loci
    54 minisatellites
    55 number
    56 pairs
    57 probe
    58 recombination signals
    59 region
    60 repeat copy number
    61 sequence
    62 signals
    63 use
    64 variable loci
    65 variation
    66 schema:name Hypervariable ‘minisatellite’ regions in human DNA
    67 schema:pagination 67-73
    68 schema:productId N64cd0387830e452bb0a7bc02920d5815
    69 N9af351f6f7cd4f9db64bba9cf0819867
    70 Ndf8945736bfa44daa22b7c7830af1407
    71 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047897100
    72 https://doi.org/10.1038/314067a0
    73 schema:sdDatePublished 2021-11-01T17:57
    74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    75 schema:sdPublisher Nf9e12753f63d4584a10b45a3776bbd60
    76 schema:url https://doi.org/10.1038/314067a0
    77 sgo:license sg:explorer/license/
    78 sgo:sdDataset articles
    79 rdf:type schema:ScholarlyArticle
    80 N08f6e67a51cc45209d1b570189a4efc6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    81 schema:name Recombination, Genetic
    82 rdf:type schema:DefinedTerm
    83 N12d28df761d948a4be7e77f124f13862 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    84 schema:name Genetic Engineering
    85 rdf:type schema:DefinedTerm
    86 N14a189ca8f7f409fa9c385510a279bbf rdf:first sg:person.01163631601.02
    87 rdf:rest Nfe098336afe443d5a145a0ad1737f5ae
    88 N1fb08511f23c4ce2b9311d7b27addd50 schema:volumeNumber 314
    89 rdf:type schema:PublicationVolume
    90 N2108e63f3f8349ecbf9807bd86e9c0b7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Alleles
    92 rdf:type schema:DefinedTerm
    93 N3ca9fe215a2640a7bd75e772a63c0a85 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Mutation
    95 rdf:type schema:DefinedTerm
    96 N4091585826c94f5c8b3cf4f14a131565 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    97 schema:name Heterozygote
    98 rdf:type schema:DefinedTerm
    99 N54897f8ac9f743218b4b13156f984326 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    100 schema:name Base Sequence
    101 rdf:type schema:DefinedTerm
    102 N5bdddaf4967c478c8b6bc871415faf84 rdf:first sg:person.01010325224.35
    103 rdf:rest N14a189ca8f7f409fa9c385510a279bbf
    104 N64cd0387830e452bb0a7bc02920d5815 schema:name dimensions_id
    105 schema:value pub.1047897100
    106 rdf:type schema:PropertyValue
    107 N7ca170634a93456cb91b239dcf33cde1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    108 schema:name Genetic Variation
    109 rdf:type schema:DefinedTerm
    110 N9af351f6f7cd4f9db64bba9cf0819867 schema:name pubmed_id
    111 schema:value 3856104
    112 rdf:type schema:PropertyValue
    113 Na5201d2dff71480ebed0e8b0d25a4c6b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    114 schema:name Nucleic Acid Hybridization
    115 rdf:type schema:DefinedTerm
    116 Nb074bfe00d8041e4aab822569710db30 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    117 schema:name Pedigree
    118 rdf:type schema:DefinedTerm
    119 Nb99aa42503374efbb0155a03618435e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    120 schema:name Humans
    121 rdf:type schema:DefinedTerm
    122 Nd30c24a924014a0cb3831c7af796524f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    123 schema:name Repetitive Sequences, Nucleic Acid
    124 rdf:type schema:DefinedTerm
    125 Ndf8945736bfa44daa22b7c7830af1407 schema:name doi
    126 schema:value 10.1038/314067a0
    127 rdf:type schema:PropertyValue
    128 Ne53d4326410c40f28e0cdcebf868b256 schema:issueNumber 6006
    129 rdf:type schema:PublicationIssue
    130 Nf9e12753f63d4584a10b45a3776bbd60 schema:name Springer Nature - SN SciGraph project
    131 rdf:type schema:Organization
    132 Nfe098336afe443d5a145a0ad1737f5ae rdf:first sg:person.01274511101.91
    133 rdf:rest rdf:nil
    134 Nfe8a834f892847bca2a1a18fb64358c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    135 schema:name Polymorphism, Genetic
    136 rdf:type schema:DefinedTerm
    137 Nff8b159a591840baac5a639e3f2435d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name DNA, Satellite
    139 rdf:type schema:DefinedTerm
    140 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    141 schema:name Biological Sciences
    142 rdf:type schema:DefinedTerm
    143 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    144 schema:name Genetics
    145 rdf:type schema:DefinedTerm
    146 sg:journal.1018957 schema:issn 0028-0836
    147 1476-4687
    148 schema:name Nature
    149 schema:publisher Springer Nature
    150 rdf:type schema:Periodical
    151 sg:person.01010325224.35 schema:affiliation grid-institutes:grid.9918.9
    152 schema:familyName Jeffreys
    153 schema:givenName Alec J.
    154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01010325224.35
    155 rdf:type schema:Person
    156 sg:person.01163631601.02 schema:affiliation grid-institutes:grid.9918.9
    157 schema:familyName Wilson
    158 schema:givenName Victoria
    159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163631601.02
    160 rdf:type schema:Person
    161 sg:person.01274511101.91 schema:affiliation grid-institutes:grid.8348.7
    162 schema:familyName Thein
    163 schema:givenName Swee Lay
    164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01274511101.91
    165 rdf:type schema:Person
    166 sg:pub.10.1007/bf00275182 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043397192
    167 https://doi.org/10.1007/bf00275182
    168 rdf:type schema:CreativeWork
    169 sg:pub.10.1038/295031a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017331230
    170 https://doi.org/10.1038/295031a0
    171 rdf:type schema:CreativeWork
    172 sg:pub.10.1038/299111a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030897036
    173 https://doi.org/10.1038/299111a0
    174 rdf:type schema:CreativeWork
    175 sg:pub.10.1038/300069a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034929435
    176 https://doi.org/10.1038/300069a0
    177 rdf:type schema:CreativeWork
    178 sg:pub.10.1038/302033a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031650611
    179 https://doi.org/10.1038/302033a0
    180 rdf:type schema:CreativeWork
    181 sg:pub.10.1038/305779a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049589192
    182 https://doi.org/10.1038/305779a0
    183 rdf:type schema:CreativeWork
    184 sg:pub.10.1038/306234a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008727690
    185 https://doi.org/10.1038/306234a0
    186 rdf:type schema:CreativeWork
    187 sg:pub.10.1038/309170a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013017501
    188 https://doi.org/10.1038/309170a0
    189 rdf:type schema:CreativeWork
    190 sg:pub.10.1038/309172a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006555130
    191 https://doi.org/10.1038/309172a0
    192 rdf:type schema:CreativeWork
    193 sg:pub.10.1038/309176a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037654366
    194 https://doi.org/10.1038/309176a0
    195 rdf:type schema:CreativeWork
    196 grid-institutes:grid.8348.7 schema:alternateName MRC Molecular Haematology Unit, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, OX3 9DU, Headington, Oxford, UK
    197 schema:name MRC Molecular Haematology Unit, Nuffield Department of Clinical Medicine, John Radcliffe Hospital, OX3 9DU, Headington, Oxford, UK
    198 rdf:type schema:Organization
    199 grid-institutes:grid.9918.9 schema:alternateName Department of Genetics, University of Leicester, University Road, LE1 7RH, Leicester, UK
    200 schema:name Department of Genetics, University of Leicester, University Road, LE1 7RH, Leicester, UK
    201 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...