Molecular genetics of Krüppel, a gene required for segmentation of the Drosophila embryo View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1985-01

AUTHORS

Anette Preiss, Urs B. Rosenberg, Andrea Kienlin, Eveline Seifert, Herbert Jäckle

ABSTRACT

Krüppel is a member of the 'gap' class of segmentation genes of Drosophila melanogaster, mutations of which cause contiguous groups of segments of the fruitfly embryo to fail to develop. In the case of Krüppel mutant embryos, thoracic and anterior abdominal segments are deleted. The molecular cloning of the Krüppel locus will lead to an understanding of the crucial role that gap genes seem to have in early embryonic development. It has already allowed the identification of a blastoderm-specific Krüppel transcript and the phenotypic rescue of mutant embryos by injected cloned DNA. More... »

PAGES

27

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/313027a0

DOI

http://dx.doi.org/10.1038/313027a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049486085

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3917552


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