Inositol trisphosphate, a novel second messenger in cellular signal transduction View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-11

AUTHORS

Michael J. Berridge, Robin F. Irvine

ABSTRACT

There has recently been rapid progress in understanding receptors that generate intracellular signals from inositol lipids. One of these lipids, phosphatidylinositol 4,5-bisphosphate, is hydrolysed to diacylglycerol and inositol trisphosphate as part of a signal transduction mechanism for controlling a variety of cellular processes including secretion, metabolism, phototransduction and cell proliferation. Diacylglycerol operates within the plane of the membrane to activate protein kinase C, whereas inositol trisphosphate is released into the cytoplasm to function as a second messenger for mobilizing intracellular calcium. More... »

PAGES

315-321

References to SciGraph publications

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  • Journal

    TITLE

    Nature

    ISSUE

    5992

    VOLUME

    312

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/312315a0

    DOI

    http://dx.doi.org/10.1038/312315a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1050116673

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6095092


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    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/312315a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/312315a0'

    RDF/XML is a standard XML format for linked data.

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