DNA sequences from the quagga, an extinct member of the horse family View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-11

AUTHORS

Russell Higuchi, Barbara Bowman, Mary Freiberger, Oliver A. Ryder, Allan C. Wilson

ABSTRACT

To determine whether DNA survives and can be recovered from the remains of extinct creatures, we have examined dried muscle from a museum specimen of the quagga, a zebra-like species (Equus quagga) that became extinct in 1883 (ref. 1). We report that DNA was extracted from this tissue in amounts approaching 1% of that expected from fresh muscle, and that the DNA was of relatively low molecular weight. Among the many clones obtained from the quagga DNA, two containing pieces of mitochondrial DNA (mtDNA) were sequenced. These sequences, comprising 229 nucleotide pairs, differ by 12 base substitutions from the corresponding sequences of mtDNA from a mountain zebra, an extant member of the genus Equus. The number, nature and locations of the substitutions imply that there has been little or no postmortem modification of the quagga DNA sequences, and that the two species had a common ancestor 3-4 Myr ago, consistent with fossil evidence concerning the age of the genus Equus. More... »

PAGES

282-284

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/312282a0

DOI

http://dx.doi.org/10.1038/312282a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1042967662

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6504142


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