Cryo-electron microscopy of viruses View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

1984-03

AUTHORS

Marc Adrian, Jacques Dubochet, Jean Lepault, Alasdair W. McDowall

ABSTRACT

Thin vitrified layers of unfixed, unstained and unsupported virus suspensions can be prepared for observation by cryo-electron microscopy in easily controlled conditions. The viral particles appear free from the kind of damage caused by dehydration, freezing or adsorption to a support that is encountered in preparing biological samples for conventional electron microscopy. Cryo-electron microscopy of vitrified specimens offers possibilities for high resolution observations that compare favourably with any other electron microscopical method. More... »

PAGES

32-36

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/308032a0

DOI

http://dx.doi.org/10.1038/308032a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046130483

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6322001


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