Alteration of c-myc chromatin structure by avian leukosis virus integration View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-02

AUTHORS

William Schubach, Mark Groudine

ABSTRACT

The most common sites of integration of the leukosis virus (ALV) long terminal repeat (LTR) in bursal lymphomas and derivative cell lines correspond to a region encompassed by two major hypersensitive sites in the 5' flanking region of the pre-integration, unrearranged c-myc gene. After integration of the ALV LTR, the major hypersensitive site within the avian c-myc oncogene region is within the proviral LTR, and the major hypersensitive sites normally found in uninfected cells 5' to the first c-myc coding exon are no longer detectable. More... »

PAGES

702-708

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/307702a0

DOI

http://dx.doi.org/10.1038/307702a0

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https://app.dimensions.ai/details/publication/pub.1050566164

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6321996


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