Ontology type: schema:ScholarlyArticle
1984-02
AUTHORSJ Downward, Y Yarden, E Mayes, G Scrace, N Totty, P Stockwell, A Ullrich, J Schlessinger, M D Waterfield
ABSTRACTEach of six peptides derived from the human epidermal growth factor (EGF) receptor very closely matches a part of the deduced sequence of the v-erb-B transforming protein of avian erythroblastosis virus (AEV). In all, the peptides contain 83 amino acid residues, 74 of which are shared with v-erb-B. The AEV progenitor may have acquired the cellular gene sequences of a truncated EGF receptor (or closely related protein) lacking the external EGF-binding domain but retaining the transmembrane domain and a domain involved in stimulating cell proliferation. Transformation of cells by AEV may result, in part, from the inappropriate acquisition of a truncated EGF receptor from the c-erb-B gene. More... »
PAGES521-527
http://scigraph.springernature.com/pub.10.1038/307521a0
DOIhttp://dx.doi.org/10.1038/307521a0
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1052686262
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/6320011
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biochemistry and Cell Biology",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Amino Acid Sequence",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Cycle",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Transformation, Viral",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Epidermal Growth Factor",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Oncogenes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptor, Epidermal Growth Factor",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptors, Cell Surface",
"type": "DefinedTerm"
}
],
"author": [
{
"familyName": "Downward",
"givenName": "J",
"id": "sg:person.01265713147.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265713147.31"
],
"type": "Person"
},
{
"familyName": "Yarden",
"givenName": "Y",
"id": "sg:person.01336614556.63",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336614556.63"
],
"type": "Person"
},
{
"familyName": "Mayes",
"givenName": "E",
"id": "sg:person.01067361133.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01067361133.41"
],
"type": "Person"
},
{
"familyName": "Scrace",
"givenName": "G",
"id": "sg:person.01132241633.91",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01132241633.91"
],
"type": "Person"
},
{
"familyName": "Totty",
"givenName": "N",
"id": "sg:person.01364023267.15",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01364023267.15"
],
"type": "Person"
},
{
"familyName": "Stockwell",
"givenName": "P",
"type": "Person"
},
{
"familyName": "Ullrich",
"givenName": "A",
"id": "sg:person.01100307217.91",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100307217.91"
],
"type": "Person"
},
{
"familyName": "Schlessinger",
"givenName": "J",
"id": "sg:person.0745312627.44",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745312627.44"
],
"type": "Person"
},
{
"familyName": "Waterfield",
"givenName": "M D",
"id": "sg:person.07416712357.72",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07416712357.72"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1073/pnas.78.12.7535",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000954068"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90477-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001376529"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0002-9378(77)90686-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002298712"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/306806a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002500811",
"https://doi.org/10.1038/306806a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.bi.52.070183.001505",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003311132"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/297205a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004078465",
"https://doi.org/10.1038/297205a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.80.3.726",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005287778"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90071-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005352469"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/272356a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007108659",
"https://doi.org/10.1038/272356a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/304035a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007830435",
"https://doi.org/10.1038/304035a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ijc.2910320208",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009814284"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/227680a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010419937",
"https://doi.org/10.1038/227680a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.79.20.6237",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011130061"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/282266a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014263785",
"https://doi.org/10.1038/282266a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90130-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015578795"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/306799a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016161777",
"https://doi.org/10.1038/306799a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90036-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018810139"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/304167a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020024289",
"https://doi.org/10.1038/304167a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-94-009-5866-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021474815",
"https://doi.org/10.1007/978-94-009-5866-1"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-94-009-5866-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021474815",
"https://doi.org/10.1007/978-94-009-5866-1"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0309-1651(83)90167-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025105574"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-2697(76)90527-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025529346"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-2697(79)90328-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027201958"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0003-9861(74)90062-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029235226"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1159/000131829",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029951206"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.80.5.1337",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030458164"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90417-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031631531"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.80.18.5627",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032353807"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1083/jcb.96.3.679",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033804284"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejm198010093031511",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034540108"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.80.12.3623",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034683094"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90019-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034760923"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jcp.1041050118",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036298293"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.74.2.565",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036371526"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.77.6.3600",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037003394"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.73.12.4555",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037392927"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02359619",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037532411",
"https://doi.org/10.1007/bf02359619"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf02359619",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037532411",
"https://doi.org/10.1007/bf02359619"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90209-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037684979"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90307-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039713021"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.78.10.6013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039938117"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.72.1.93",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042648768"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/305605a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043416987",
"https://doi.org/10.1038/305605a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/306760a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043435557",
"https://doi.org/10.1038/306760a0"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(82)90070-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044131407"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(83)90513-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046443145"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0092-8674(82)90383-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047048382"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jcp.1040810205",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047346694"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.79.2.485",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048325029"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.75.8.4001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051169626"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/jcb.240200207",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052427608"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.80.15.4684",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053722724"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.6304883",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062636677"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.6310754",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062636710"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1076087236",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079574539",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081563101",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081657047",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081658598",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081658640",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081669828",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081670860",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081670907",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1081673553",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/j.1460-2075.1984.tb01777.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1081679088"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082249837",
"type": "CreativeWork"
}
],
"datePublished": "1984-02",
"datePublishedReg": "1984-02-01",
"description": "Each of six peptides derived from the human epidermal growth factor (EGF) receptor very closely matches a part of the deduced sequence of the v-erb-B transforming protein of avian erythroblastosis virus (AEV). In all, the peptides contain 83 amino acid residues, 74 of which are shared with v-erb-B. The AEV progenitor may have acquired the cellular gene sequences of a truncated EGF receptor (or closely related protein) lacking the external EGF-binding domain but retaining the transmembrane domain and a domain involved in stimulating cell proliferation. Transformation of cells by AEV may result, in part, from the inappropriate acquisition of a truncated EGF receptor from the c-erb-B gene.",
"genre": "research_article",
"id": "sg:pub.10.1038/307521a0",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.2466472",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1018957",
"issn": [
"0090-0028",
"1476-4687"
],
"name": "Nature",
"type": "Periodical"
},
{
"issueNumber": "5951",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "307"
}
],
"name": "Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences",
"pagination": "521-527",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"faf606105fa111fa8b080afe930deee188b64253c1f790d449ff519610a21e7b"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"6320011"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"0410462"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/307521a0"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1052686262"
]
}
],
"sameAs": [
"https://doi.org/10.1038/307521a0",
"https://app.dimensions.ai/details/publication/pub.1052686262"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-10T13:56",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000426.jsonl",
"type": "ScholarlyArticle",
"url": "http://www.nature.com/nature/journal/v307/n5951/full/307521a0.html"
}
]
Download the RDF metadata as:Â json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/307521a0'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/307521a0'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/307521a0'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/307521a0'
This table displays all metadata directly associated to this object as RDF triples.
339 TRIPLES
21 PREDICATES
101 URIs
29 LITERALS
17 BLANK NODES