Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1984-01

AUTHORS

Attila T. Lörincz, Steven I. Reed

ABSTRACT

In the budding yeast, Saccharomyces cerevisiae, division is controlled in response to nutrient limitation and in preparation for conjugation. Cells deprived of an essential nutrient or responding to mating pheromones cease division and become synchronous in the G1 interval, apparently constrained from completing a critical event. This event has been given the operational designation of 'start'. We have isolated a large number of start mutations which confer on S. cerevisiae cells a conditional inability to complete start (Fig. 1) presumably because they define genes which must be expressed for the start event to be successfully completed. We have described the isolation on plasmids of one of the start genes, CDC28, by genetic complementation and initial characterization of its product. We now describe the DNA sequence of the gene CDC28. More... »

PAGES

183-185

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/307183a0

DOI

http://dx.doi.org/10.1038/307183a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024981692

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6361575


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA, Fungal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genes, Fungal", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Growth Substances", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oncogenes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Kinases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Saccharomyces cerevisiae", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "L\u00f6rincz", 
        "givenName": "Attila T.", 
        "id": "sg:person.01341322342.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341322342.00"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Reed", 
        "givenName": "Steven I.", 
        "id": "sg:person.014417232732.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014417232732.54"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/304219a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008096441", 
          "https://doi.org/10.1038/304219a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.77.4.2119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014842740"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.79.9.2836", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018729188"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/289258a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018787893", 
          "https://doi.org/10.1038/289258a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4827(77)90154-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021182171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.74.12.5463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025360556"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-4827(73)90424-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030715075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.78.2.848", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035524696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(77)90272-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035888199"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(82)90044-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036559465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(82)90044-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036559465"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(83)90345-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040866380"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/300706a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050973343", 
          "https://doi.org/10.1038/300706a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.2.4.412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052201928"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.183.4120.46", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062508832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7280687", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062645221"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081689947", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082093759", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1984-01", 
    "datePublishedReg": "1984-01-01", 
    "description": "In the budding yeast, Saccharomyces cerevisiae, division is controlled in response to nutrient limitation and in preparation for conjugation. Cells deprived of an essential nutrient or responding to mating pheromones cease division and become synchronous in the G1 interval, apparently constrained from completing a critical event. This event has been given the operational designation of 'start'. We have isolated a large number of start mutations which confer on S. cerevisiae cells a conditional inability to complete start (Fig. 1) presumably because they define genes which must be expressed for the start event to be successfully completed. We have described the isolation on plasmids of one of the start genes, CDC28, by genetic complementation and initial characterization of its product. We now describe the DNA sequence of the gene CDC28.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/307183a0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2509554", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5947", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "307"
      }
    ], 
    "name": "Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes", 
    "pagination": "183-185", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "7702b0cecac1b56503f8acdd6c3517e76c18b4ee850ab9399d58eb3dad9c051c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6361575"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/307183a0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1024981692"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/307183a0", 
      "https://app.dimensions.ai/details/publication/pub.1024981692"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T20:34", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000424.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/307183a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/307183a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/307183a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/307183a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/307183a0'


 

This table displays all metadata directly associated to this object as RDF triples.

161 TRIPLES      21 PREDICATES      55 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/307183a0 schema:about N026006ce5a9f49ba827b0abe707f471d
2 N0771512419ca492f9f94962d89d7800e
3 N14fde73259634d0dba9d244b7cb3d375
4 N65962dc4a4ba4cee88722637024515c9
5 N67c3b454bcf2424f9ad403fc395fd753
6 N8988e9e386a8409ca10af33fda84d02e
7 N8fa8e94546754d6aab00cb5c8bb86fd1
8 N98f9659d3b724afd846e90fde5c4d7f2
9 Nec67a0ae424e4b6db181ac78350c4c99
10 anzsrc-for:06
11 anzsrc-for:0604
12 schema:author Nc872f76b849747ada42206ebb3cff20b
13 schema:citation sg:pub.10.1038/289258a0
14 sg:pub.10.1038/300706a0
15 sg:pub.10.1038/304219a0
16 https://app.dimensions.ai/details/publication/pub.1081689947
17 https://app.dimensions.ai/details/publication/pub.1082093759
18 https://doi.org/10.1016/0014-4827(73)90424-2
19 https://doi.org/10.1016/0014-4827(77)90154-9
20 https://doi.org/10.1016/0092-8674(77)90272-0
21 https://doi.org/10.1016/0092-8674(83)90345-8
22 https://doi.org/10.1016/0378-1119(82)90044-0
23 https://doi.org/10.1073/pnas.74.12.5463
24 https://doi.org/10.1073/pnas.77.4.2119
25 https://doi.org/10.1073/pnas.78.2.848
26 https://doi.org/10.1073/pnas.79.9.2836
27 https://doi.org/10.1126/science.183.4120.46
28 https://doi.org/10.1126/science.7280687
29 https://doi.org/10.1128/mcb.2.4.412
30 schema:datePublished 1984-01
31 schema:datePublishedReg 1984-01-01
32 schema:description In the budding yeast, Saccharomyces cerevisiae, division is controlled in response to nutrient limitation and in preparation for conjugation. Cells deprived of an essential nutrient or responding to mating pheromones cease division and become synchronous in the G1 interval, apparently constrained from completing a critical event. This event has been given the operational designation of 'start'. We have isolated a large number of start mutations which confer on S. cerevisiae cells a conditional inability to complete start (Fig. 1) presumably because they define genes which must be expressed for the start event to be successfully completed. We have described the isolation on plasmids of one of the start genes, CDC28, by genetic complementation and initial characterization of its product. We now describe the DNA sequence of the gene CDC28.
33 schema:genre research_article
34 schema:inLanguage en
35 schema:isAccessibleForFree false
36 schema:isPartOf N3a80b2af845b40ad947ab92907ff27ea
37 Ncede4e7bf18f4729b8395f5d41ffe643
38 sg:journal.1018957
39 schema:name Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes
40 schema:pagination 183-185
41 schema:productId N546fd36f275543d695a2cf7658fc45bd
42 N55d97bbc390149ed8b38f6cfd80afc74
43 N7703aff8e2d24444a5a289896303b4a6
44 N9dfdf2397cf84b69962e87028b5152c2
45 Na303923dac244ef380dfb9b4b66ba716
46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024981692
47 https://doi.org/10.1038/307183a0
48 schema:sdDatePublished 2019-04-10T20:34
49 schema:sdLicense https://scigraph.springernature.com/explorer/license/
50 schema:sdPublisher N0347fdbd16cd44e59a44ca1c37a8d58f
51 schema:url http://www.nature.com/articles/307183a0
52 sgo:license sg:explorer/license/
53 sgo:sdDataset articles
54 rdf:type schema:ScholarlyArticle
55 N026006ce5a9f49ba827b0abe707f471d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
56 schema:name Oncogenes
57 rdf:type schema:DefinedTerm
58 N0347fdbd16cd44e59a44ca1c37a8d58f schema:name Springer Nature - SN SciGraph project
59 rdf:type schema:Organization
60 N0771512419ca492f9f94962d89d7800e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
61 schema:name Saccharomyces cerevisiae
62 rdf:type schema:DefinedTerm
63 N14fde73259634d0dba9d244b7cb3d375 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
64 schema:name Growth Substances
65 rdf:type schema:DefinedTerm
66 N3a80b2af845b40ad947ab92907ff27ea schema:issueNumber 5947
67 rdf:type schema:PublicationIssue
68 N546fd36f275543d695a2cf7658fc45bd schema:name dimensions_id
69 schema:value pub.1024981692
70 rdf:type schema:PropertyValue
71 N55d97bbc390149ed8b38f6cfd80afc74 schema:name pubmed_id
72 schema:value 6361575
73 rdf:type schema:PropertyValue
74 N65962dc4a4ba4cee88722637024515c9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Amino Acid Sequence
76 rdf:type schema:DefinedTerm
77 N67c3b454bcf2424f9ad403fc395fd753 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Genes, Fungal
79 rdf:type schema:DefinedTerm
80 N7703aff8e2d24444a5a289896303b4a6 schema:name readcube_id
81 schema:value 7702b0cecac1b56503f8acdd6c3517e76c18b4ee850ab9399d58eb3dad9c051c
82 rdf:type schema:PropertyValue
83 N8988e9e386a8409ca10af33fda84d02e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name DNA, Fungal
85 rdf:type schema:DefinedTerm
86 N8fa8e94546754d6aab00cb5c8bb86fd1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
87 schema:name Protein Kinases
88 rdf:type schema:DefinedTerm
89 N98f9659d3b724afd846e90fde5c4d7f2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
90 schema:name Animals
91 rdf:type schema:DefinedTerm
92 N9dfdf2397cf84b69962e87028b5152c2 schema:name nlm_unique_id
93 schema:value 0410462
94 rdf:type schema:PropertyValue
95 Na303923dac244ef380dfb9b4b66ba716 schema:name doi
96 schema:value 10.1038/307183a0
97 rdf:type schema:PropertyValue
98 Nc872f76b849747ada42206ebb3cff20b rdf:first sg:person.01341322342.00
99 rdf:rest Ne8e90e15dce94ad8b0bc9bf583ea31c0
100 Ncede4e7bf18f4729b8395f5d41ffe643 schema:volumeNumber 307
101 rdf:type schema:PublicationVolume
102 Ne8e90e15dce94ad8b0bc9bf583ea31c0 rdf:first sg:person.014417232732.54
103 rdf:rest rdf:nil
104 Nec67a0ae424e4b6db181ac78350c4c99 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Base Sequence
106 rdf:type schema:DefinedTerm
107 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
108 schema:name Biological Sciences
109 rdf:type schema:DefinedTerm
110 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
111 schema:name Genetics
112 rdf:type schema:DefinedTerm
113 sg:grant.2509554 http://pending.schema.org/fundedItem sg:pub.10.1038/307183a0
114 rdf:type schema:MonetaryGrant
115 sg:journal.1018957 schema:issn 0090-0028
116 1476-4687
117 schema:name Nature
118 rdf:type schema:Periodical
119 sg:person.01341322342.00 schema:familyName Lörincz
120 schema:givenName Attila T.
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01341322342.00
122 rdf:type schema:Person
123 sg:person.014417232732.54 schema:familyName Reed
124 schema:givenName Steven I.
125 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014417232732.54
126 rdf:type schema:Person
127 sg:pub.10.1038/289258a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018787893
128 https://doi.org/10.1038/289258a0
129 rdf:type schema:CreativeWork
130 sg:pub.10.1038/300706a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050973343
131 https://doi.org/10.1038/300706a0
132 rdf:type schema:CreativeWork
133 sg:pub.10.1038/304219a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008096441
134 https://doi.org/10.1038/304219a0
135 rdf:type schema:CreativeWork
136 https://app.dimensions.ai/details/publication/pub.1081689947 schema:CreativeWork
137 https://app.dimensions.ai/details/publication/pub.1082093759 schema:CreativeWork
138 https://doi.org/10.1016/0014-4827(73)90424-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030715075
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1016/0014-4827(77)90154-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021182171
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1016/0092-8674(77)90272-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035888199
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1016/0092-8674(83)90345-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040866380
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1016/0378-1119(82)90044-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036559465
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1073/pnas.74.12.5463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025360556
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1073/pnas.77.4.2119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014842740
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1073/pnas.78.2.848 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035524696
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1073/pnas.79.9.2836 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018729188
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1126/science.183.4120.46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062508832
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1126/science.7280687 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062645221
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1128/mcb.2.4.412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052201928
161 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...