Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1983-12

AUTHORS

T. H. Rabbitts, P. H. Hamlyn, R. Baer

ABSTRACT

The nucleotide sequence of a translocated c-myc gene in a Burkitt lymphoma reveals multiple base changes in the coding region. Twenty-five base changes, generating 16 codon alterations, were found in the first coding exon; no changes occur in the second coding exon. These changes are probably the result of somatic mutations that occurred during and after translocation, and may contribute to oncogenesis by allowing synthesis of an altered c-myc gene product. More... »

PAGES

760-765

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/306760a0

DOI

http://dx.doi.org/10.1038/306760a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043435557

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6419122


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