Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1983-08

AUTHORS

Martin Kreitman

ABSTRACT

The sequencing of eleven cloned Drosophila melanogaster alcohol dehydrogenase (Adh) genes from five natural populations has revealed a large number of previously hidden polymorphisms. Only one of the 43 polymorphisms results in an amino acid change, the one responsible for the two electrophoretic variants (fast, Adh-f, and slow, Adh-s) found in nearly all natural populations. The implication is that most amino acid changes in Adh would be selectively deleterious. More... »

PAGES

412-417

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/304412a0

DOI

http://dx.doi.org/10.1038/304412a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010901342

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6410283


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