The sequences of an expressed rat α-tubulin gene and a pseudogene with an inserted repetitive element View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-11

AUTHORS

Ihor Lemischka, Phillip A. Sharp

ABSTRACT

The rat genome contains two segments closely related to a rat α-tubulin mRNA. Both have been cloned and complete nucleotide sequences are presented. Analysis of the structure and sequence of one of these establishes it as a functional α-tubulin gene. The second segment is a processed α-tubulin pseudogene. Comparison of this pseudogene to the mRNA and gene coding for α-tubulin strongly suggests that a mature mRNA was involved in its origin. Features of the pseudogene and a dispersed repetitive element inserted within it possibly reflect a common RNA-mediated process of insertion. More... »

PAGES

330-335

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/300330a0

DOI

http://dx.doi.org/10.1038/300330a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1006486090

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6927856


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