Molecular structure of r(GCG)d(TATACGC): a DNA–RNA hybrid helix joined to double helical DNA View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-10

AUTHORS

Andrew H.-J. Wang, Satoshi Fujii, Jacques H. van Boom, Gijs A. van der Marel, Stan A. A. van Boeckel, Alexander Rich

ABSTRACT

The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA hybrid segments surrounding a central region of double helical DNA; its molecular structure has been solved by X-ray analysis. All three parts of the molecule adopt a conformation which is close to that seen in the 11-fold RNA double helix. The conformation of the ribonucleotides is partly determined by water molecules bridging between the ribose O2' hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no structural discontinuities. However, the central DNA TATA sequence has some structural irregularities. More... »

PAGES

601-604

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/299601a0

DOI

http://dx.doi.org/10.1038/299601a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1036648503

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6181416


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