Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-07

AUTHORS

James L. Bittle, Richard A. Houghten, Hannah Alexander, Thomas M. Shinnick, J. Gregor Sutcliffe, Richard A. Lerner, David J. Rowlands, Fred Brown

ABSTRACT

Chemically synthesized peptides corresponding to two different regions of the VP1 polypeptide of foot-and-mouth disease virus (FMDV) produced high levels of serotype-specific virus neutralizing antibody in cattle, guinea pigs and rabbits. A single inoculation of one of these peptides protected guinea pigs against subsequent challenge with the virulent virus.

PAGES

30-33

Journal

TITLE

Nature

ISSUE

5869

VOLUME

298

Related Patents

  • Rodent Hepatitis B Virus Core Proteins As Vaccine Platforms And Methods Of Use Thereof
  • Polypeptides And Antibodies Related To Deglycosylated Viral Glycoproteins
  • Hepatitis B Surface Antigen Vaccine
  • Amino Acid Sequences And Polypeptides Including These Sequences And Having The Specificity Of Foot And Mouth Disease And Other Viral Antigens
  • Novel Antigens And Vaccines Containing Them
  • Synthetic Picornavirus Antigen.
  • Amino Acid Sequences; For Increased Immunogenicity
  • Characterization Of Oncogenes And Assays Based Thereon
  • Method Of Producing An Antibody Capable Of Detecting The Presence Of A Human Oncogene.
  • Radiolabeled Or Enzyme Labeled Peptides
  • Hepatitis B Surface Antigen Vaccine
  • Hepatitis Virus Core Proteins As Vaccine Platforms And Methods Of Use Thereof
  • A Immunization Product To Prevent Viral Infection
  • Rodent Hepatitis B Virus Core Proteins As Vaccine Platforms And Methods Of Use Thereof
  • Human Hepatitis B Virus Core Proteins As Vaccine Platforms And Methods Of Use Thereof
  • Amino Acid Sequences And Polypeptides Including These Sequences And Having The Specificity Of Foot And Mouth Disease And Other Viral Antigens
  • Peptides Derived From The Non-Structural Proteins Of Foot And Mouth Disease Virus As Diagnostic Reagents
  • Synthetic Picornavirus Antigen
  • Synthetic Picornavirus Antigen
  • Synthetic Vaccines For Foot And Mouth Disease
  • Hepatitis B Surface Antigen Vaccine
  • Composition Used As A Therapeutic Agent Against Chronic Viral Hepatic Diseases
  • Recombinant Dna Of An Expression Regulatory Sequence Operatively Linked To First And Second Dna Sequences Which Encode Pre-S1 Peptide Epitope And Surface Antigen Peptide; Production Of Immunogenic Particles For Vaccine
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/298030a0

    DOI

    http://dx.doi.org/10.1038/298030a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1049090502

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7045684


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/07", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Agricultural and Veterinary Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0707", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Veterinary Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Amino Acid Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Base Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA, Recombinant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Escherichia coli", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Foot-and-Mouth Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Guinea Pigs", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Immunotherapy", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Peptides", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plasmids", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Protein Biosynthesis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Rabbits", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.214007.0", 
              "name": [
                "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bittle", 
            "givenName": "James L.", 
            "id": "sg:person.01056372453.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056372453.08"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.214007.0", 
              "name": [
                "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Houghten", 
            "givenName": "Richard A.", 
            "id": "sg:person.01020157344.12", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020157344.12"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.214007.0", 
              "name": [
                "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Alexander", 
            "givenName": "Hannah", 
            "id": "sg:person.0763171305.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763171305.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.214007.0", 
              "name": [
                "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shinnick", 
            "givenName": "Thomas M.", 
            "id": "sg:person.0722552124.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722552124.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.214007.0", 
              "name": [
                "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sutcliffe", 
            "givenName": "J. Gregor", 
            "id": "sg:person.01051423703.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051423703.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA", 
              "id": "http://www.grid.ac/institutes/grid.214007.0", 
              "name": [
                "Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lerner", 
            "givenName": "Richard A.", 
            "id": "sg:person.01127276005.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127276005.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Animal Virus Research Institute, GU24 0NF, Pirbright, Surrey, UK", 
              "id": "http://www.grid.ac/institutes/grid.63622.33", 
              "name": [
                "Animal Virus Research Institute, GU24 0NF, Pirbright, Surrey, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rowlands", 
            "givenName": "David J.", 
            "id": "sg:person.0672233670.67", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672233670.67"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Animal Virus Research Institute, GU24 0NF, Pirbright, Surrey, UK", 
              "id": "http://www.grid.ac/institutes/grid.63622.33", 
              "name": [
                "Animal Virus Research Institute, GU24 0NF, Pirbright, Surrey, UK"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brown", 
            "givenName": "Fred", 
            "id": "sg:person.01350725627.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350725627.48"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/290800a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002634567", 
              "https://doi.org/10.1038/290800a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/227680a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010419937", 
              "https://doi.org/10.1038/227680a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/287801a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018637284", 
              "https://doi.org/10.1038/287801a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/289555a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021160314", 
              "https://doi.org/10.1038/289555a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/293479a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020611299", 
              "https://doi.org/10.1038/293479a0"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1982-07", 
        "datePublishedReg": "1982-07-01", 
        "description": "Chemically synthesized peptides corresponding to two different regions of the VP1 polypeptide of foot-and-mouth disease virus (FMDV) produced high levels of serotype-specific virus neutralizing antibody in cattle, guinea pigs and rabbits. A single inoculation of one of these peptides protected guinea pigs against subsequent challenge with the virulent virus.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/298030a0", 
        "isAccessibleForFree": false, 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0028-0836", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5869", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "298"
          }
        ], 
        "keywords": [
          "mouth disease virus", 
          "single inoculation", 
          "virulent virus", 
          "mouth disease", 
          "disease virus", 
          "pigs", 
          "viral nucleotide sequences", 
          "subsequent challenge", 
          "cattle", 
          "virus", 
          "inoculation", 
          "different regions", 
          "high levels", 
          "guinea pigs", 
          "nucleotide sequence", 
          "foot", 
          "protection", 
          "region", 
          "levels", 
          "disease", 
          "challenges", 
          "immunization", 
          "sequence", 
          "rabbits", 
          "antibodies", 
          "peptides", 
          "polypeptide", 
          "VP1 polypeptide"
        ], 
        "name": "Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence", 
        "pagination": "30-33", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1049090502"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/298030a0"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "7045684"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/298030a0", 
          "https://app.dimensions.ai/details/publication/pub.1049090502"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-10-01T06:27", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/article/article_159.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/298030a0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/298030a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/298030a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/298030a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/298030a0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    209 TRIPLES      21 PREDICATES      71 URIs      58 LITERALS      19 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/298030a0 schema:about N18200bdd8eae43fd87aba71fa6d22ec5
    2 N1a757d95a12346f19740536d91bd65c6
    3 N1dba6398dffc461a8cb05d5a4ff48901
    4 N3ae13305146644edbe85bf403f0301ec
    5 N3d57e2fe38274fbf97bfa37c4f7b9b01
    6 N43719e8e8eca4075948aea236660730c
    7 N59c0da2db2584828ae29b120323f79f6
    8 N9c7274dc0515407ba7cea7678d72c3e1
    9 Nd8bae61e003d4c22a6c6ada636f1139d
    10 Neda752eea94c4f6d99d28895a3d9bf6b
    11 Nf45b372d4da844e4bbf79a8448b70360
    12 Nf973643846d041f99aae4beef978a899
    13 anzsrc-for:07
    14 anzsrc-for:0707
    15 schema:author Nf4e687f358bd4e4fac125c388913cfc4
    16 schema:citation sg:pub.10.1038/227680a0
    17 sg:pub.10.1038/287801a0
    18 sg:pub.10.1038/289555a0
    19 sg:pub.10.1038/290800a0
    20 sg:pub.10.1038/293479a0
    21 schema:datePublished 1982-07
    22 schema:datePublishedReg 1982-07-01
    23 schema:description Chemically synthesized peptides corresponding to two different regions of the VP1 polypeptide of foot-and-mouth disease virus (FMDV) produced high levels of serotype-specific virus neutralizing antibody in cattle, guinea pigs and rabbits. A single inoculation of one of these peptides protected guinea pigs against subsequent challenge with the virulent virus.
    24 schema:genre article
    25 schema:isAccessibleForFree false
    26 schema:isPartOf N67f47de742724617a866f00dc9ec7b49
    27 N7718400da0044c939f307df35c9b477e
    28 sg:journal.1018957
    29 schema:keywords VP1 polypeptide
    30 antibodies
    31 cattle
    32 challenges
    33 different regions
    34 disease
    35 disease virus
    36 foot
    37 guinea pigs
    38 high levels
    39 immunization
    40 inoculation
    41 levels
    42 mouth disease
    43 mouth disease virus
    44 nucleotide sequence
    45 peptides
    46 pigs
    47 polypeptide
    48 protection
    49 rabbits
    50 region
    51 sequence
    52 single inoculation
    53 subsequent challenge
    54 viral nucleotide sequences
    55 virulent virus
    56 virus
    57 schema:name Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence
    58 schema:pagination 30-33
    59 schema:productId N1a34e31f869840f9b7f9d9f45d935c5d
    60 N50be2750dbac47668ae97cb2382e1e99
    61 Nb0b33eedf0cb4b6590bf87fd624daedf
    62 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049090502
    63 https://doi.org/10.1038/298030a0
    64 schema:sdDatePublished 2022-10-01T06:27
    65 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    66 schema:sdPublisher N54a2e6d2be364202ba1b97aec4f6c5ac
    67 schema:url https://doi.org/10.1038/298030a0
    68 sgo:license sg:explorer/license/
    69 sgo:sdDataset articles
    70 rdf:type schema:ScholarlyArticle
    71 N18200bdd8eae43fd87aba71fa6d22ec5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    72 schema:name Animals
    73 rdf:type schema:DefinedTerm
    74 N1a34e31f869840f9b7f9d9f45d935c5d schema:name pubmed_id
    75 schema:value 7045684
    76 rdf:type schema:PropertyValue
    77 N1a757d95a12346f19740536d91bd65c6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    78 schema:name Escherichia coli
    79 rdf:type schema:DefinedTerm
    80 N1dba6398dffc461a8cb05d5a4ff48901 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    81 schema:name DNA, Recombinant
    82 rdf:type schema:DefinedTerm
    83 N216971f64e61413291f9be5cfce4d135 rdf:first sg:person.01127276005.74
    84 rdf:rest Naade7229a847443f8c90fb6f79322da7
    85 N3ae13305146644edbe85bf403f0301ec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name Plasmids
    87 rdf:type schema:DefinedTerm
    88 N3d57e2fe38274fbf97bfa37c4f7b9b01 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    89 schema:name Protein Biosynthesis
    90 rdf:type schema:DefinedTerm
    91 N43719e8e8eca4075948aea236660730c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    92 schema:name Guinea Pigs
    93 rdf:type schema:DefinedTerm
    94 N50be2750dbac47668ae97cb2382e1e99 schema:name dimensions_id
    95 schema:value pub.1049090502
    96 rdf:type schema:PropertyValue
    97 N54a2e6d2be364202ba1b97aec4f6c5ac schema:name Springer Nature - SN SciGraph project
    98 rdf:type schema:Organization
    99 N59c0da2db2584828ae29b120323f79f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    100 schema:name Base Sequence
    101 rdf:type schema:DefinedTerm
    102 N67f47de742724617a866f00dc9ec7b49 schema:issueNumber 5869
    103 rdf:type schema:PublicationIssue
    104 N69acbde603c145038c57283c26785cd1 rdf:first sg:person.01051423703.27
    105 rdf:rest N216971f64e61413291f9be5cfce4d135
    106 N7718400da0044c939f307df35c9b477e schema:volumeNumber 298
    107 rdf:type schema:PublicationVolume
    108 N91a0370931874602a0de7c7de4ae7f42 rdf:first sg:person.0763171305.05
    109 rdf:rest Nbbf2941843054678b2d03c613c2cf35e
    110 N9c7274dc0515407ba7cea7678d72c3e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name Peptides
    112 rdf:type schema:DefinedTerm
    113 Naade7229a847443f8c90fb6f79322da7 rdf:first sg:person.0672233670.67
    114 rdf:rest Nee07f7fd4b79471685a1876def1047e0
    115 Nb0b33eedf0cb4b6590bf87fd624daedf schema:name doi
    116 schema:value 10.1038/298030a0
    117 rdf:type schema:PropertyValue
    118 Nbbf2941843054678b2d03c613c2cf35e rdf:first sg:person.0722552124.56
    119 rdf:rest N69acbde603c145038c57283c26785cd1
    120 Nd8bae61e003d4c22a6c6ada636f1139d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    121 schema:name Immunotherapy
    122 rdf:type schema:DefinedTerm
    123 Ne6bb16020d984a71972ede9ef468e011 rdf:first sg:person.01020157344.12
    124 rdf:rest N91a0370931874602a0de7c7de4ae7f42
    125 Neda752eea94c4f6d99d28895a3d9bf6b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    126 schema:name Amino Acid Sequence
    127 rdf:type schema:DefinedTerm
    128 Nee07f7fd4b79471685a1876def1047e0 rdf:first sg:person.01350725627.48
    129 rdf:rest rdf:nil
    130 Nf45b372d4da844e4bbf79a8448b70360 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    131 schema:name Rabbits
    132 rdf:type schema:DefinedTerm
    133 Nf4e687f358bd4e4fac125c388913cfc4 rdf:first sg:person.01056372453.08
    134 rdf:rest Ne6bb16020d984a71972ede9ef468e011
    135 Nf973643846d041f99aae4beef978a899 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    136 schema:name Foot-and-Mouth Disease
    137 rdf:type schema:DefinedTerm
    138 anzsrc-for:07 schema:inDefinedTermSet anzsrc-for:
    139 schema:name Agricultural and Veterinary Sciences
    140 rdf:type schema:DefinedTerm
    141 anzsrc-for:0707 schema:inDefinedTermSet anzsrc-for:
    142 schema:name Veterinary Sciences
    143 rdf:type schema:DefinedTerm
    144 sg:journal.1018957 schema:issn 0028-0836
    145 1476-4687
    146 schema:name Nature
    147 schema:publisher Springer Nature
    148 rdf:type schema:Periodical
    149 sg:person.01020157344.12 schema:affiliation grid-institutes:grid.214007.0
    150 schema:familyName Houghten
    151 schema:givenName Richard A.
    152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01020157344.12
    153 rdf:type schema:Person
    154 sg:person.01051423703.27 schema:affiliation grid-institutes:grid.214007.0
    155 schema:familyName Sutcliffe
    156 schema:givenName J. Gregor
    157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051423703.27
    158 rdf:type schema:Person
    159 sg:person.01056372453.08 schema:affiliation grid-institutes:grid.214007.0
    160 schema:familyName Bittle
    161 schema:givenName James L.
    162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01056372453.08
    163 rdf:type schema:Person
    164 sg:person.01127276005.74 schema:affiliation grid-institutes:grid.214007.0
    165 schema:familyName Lerner
    166 schema:givenName Richard A.
    167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01127276005.74
    168 rdf:type schema:Person
    169 sg:person.01350725627.48 schema:affiliation grid-institutes:grid.63622.33
    170 schema:familyName Brown
    171 schema:givenName Fred
    172 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350725627.48
    173 rdf:type schema:Person
    174 sg:person.0672233670.67 schema:affiliation grid-institutes:grid.63622.33
    175 schema:familyName Rowlands
    176 schema:givenName David J.
    177 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0672233670.67
    178 rdf:type schema:Person
    179 sg:person.0722552124.56 schema:affiliation grid-institutes:grid.214007.0
    180 schema:familyName Shinnick
    181 schema:givenName Thomas M.
    182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0722552124.56
    183 rdf:type schema:Person
    184 sg:person.0763171305.05 schema:affiliation grid-institutes:grid.214007.0
    185 schema:familyName Alexander
    186 schema:givenName Hannah
    187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0763171305.05
    188 rdf:type schema:Person
    189 sg:pub.10.1038/227680a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010419937
    190 https://doi.org/10.1038/227680a0
    191 rdf:type schema:CreativeWork
    192 sg:pub.10.1038/287801a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018637284
    193 https://doi.org/10.1038/287801a0
    194 rdf:type schema:CreativeWork
    195 sg:pub.10.1038/289555a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021160314
    196 https://doi.org/10.1038/289555a0
    197 rdf:type schema:CreativeWork
    198 sg:pub.10.1038/290800a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002634567
    199 https://doi.org/10.1038/290800a0
    200 rdf:type schema:CreativeWork
    201 sg:pub.10.1038/293479a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020611299
    202 https://doi.org/10.1038/293479a0
    203 rdf:type schema:CreativeWork
    204 grid-institutes:grid.214007.0 schema:alternateName Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA
    205 schema:name Committee for the Study of Molecular Genetics, Research Institute of Scripps Clinic, 92037, La Jolla, California, USA
    206 rdf:type schema:Organization
    207 grid-institutes:grid.63622.33 schema:alternateName Animal Virus Research Institute, GU24 0NF, Pirbright, Surrey, UK
    208 schema:name Animal Virus Research Institute, GU24 0NF, Pirbright, Surrey, UK
    209 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...