The role of protein phosphorylation in neural and hormonal control of cellular activity View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1982-04

AUTHORS

Philip Cohen

ABSTRACT

Protein phosphorylation is now recognized to be the major general mechanism by which intracellular events in mammalian tissues are controlled by external physiological stimuli. However, only recently has the idea that different cellular functions are controlled by common protein kinases and protein phosphatases started to gain widespread acceptance. Thus there is an integrated network of regulatory pathways, mediated by phosphorylation–dephosphorylation, that allows diverse cellular events to be coordinated by neural and hormonal stimuli. The evidence that supports this concept is reviewed, with emphasis on the role of protein phosphorylation in enzyme regulation. More... »

PAGES

613-620

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/296613a0

DOI

http://dx.doi.org/10.1038/296613a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035034012

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6280056


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