Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T ... View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-12

AUTHORS

Isao Miyoshi, Ichiro Kubonishi, Shizuo Yoshimoto, Tadaatsu Akagi, Yuji Ohtsuki, Yukimasa Shiraishi, Kinya Nagata, Yorio Hinuma

ABSTRACT

A recent nationwide survey of the lymphocyte subpopulations of leukaemia and lymphoma in Japan has disclosed a high incidence of adult T-cell leukaemia (ATL)1. One of the striking features of this disease is the clustering of patients in the southwestern part of Japan1,2. We have established a continuous culture line of leukaemic T cells from a patient with ATL3,4. This cell line, MT-1, was found to carry type C virus particles and ATL-associated antigens (ATLA) which specifically reacted with sera from all ATL patients and about 25% of healthy adults in the endemic area5. We report here that by co-culture of ATL cells from a female patient and normal human cord leukocytes from a male infant, a T-cell line of cord leukocyte origin was established. Numerous type C virus particles as well as ATLA were detected in this cell line. More... »

PAGES

770-771

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/294770a0

DOI

http://dx.doi.org/10.1038/294770a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005819260

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6275274


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antigens, Neoplasm", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Line", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Inclusion Bodies, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Leukemia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Retroviridae", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "T-Lymphocytes", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "familyName": "Miyoshi", 
        "givenName": "Isao", 
        "id": "sg:person.01051066610.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051066610.52"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Kubonishi", 
        "givenName": "Ichiro", 
        "id": "sg:person.01060701147.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060701147.16"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Yoshimoto", 
        "givenName": "Shizuo", 
        "id": "sg:person.0651045615.03", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651045615.03"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Akagi", 
        "givenName": "Tadaatsu", 
        "id": "sg:person.010520137352.96", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010520137352.96"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Ohtsuki", 
        "givenName": "Yuji", 
        "id": "sg:person.0777010316.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777010316.75"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Shiraishi", 
        "givenName": "Yukimasa", 
        "id": "sg:person.01120516555.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120516555.60"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Nagata", 
        "givenName": "Kinya", 
        "id": "sg:person.01335205436.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335205436.29"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Hinuma", 
        "givenName": "Yorio", 
        "id": "sg:person.01335063603.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335063603.32"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.77.3.1617", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029171498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.77.12.7415", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048965236"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079509088", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082072821", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1981-12", 
    "datePublishedReg": "1981-12-01", 
    "description": "A recent nationwide survey of the lymphocyte subpopulations of leukaemia and lymphoma in Japan has disclosed a high incidence of adult T-cell leukaemia (ATL)1. One of the striking features of this disease is the clustering of patients in the southwestern part of Japan1,2. We have established a continuous culture line of leukaemic T cells from a patient with ATL3,4. This cell line, MT-1, was found to carry type C virus particles and ATL-associated antigens (ATLA) which specifically reacted with sera from all ATL patients and about 25% of healthy adults in the endemic area5. We report here that by co-culture of ATL cells from a female patient and normal human cord leukocytes from a male infant, a T-cell line of cord leukocyte origin was established. Numerous type C virus particles as well as ATLA were detected in this cell line.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/294770a0", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1018957", 
        "issn": [
          "0090-0028", 
          "1476-4687"
        ], 
        "name": "Nature", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "5843", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "294"
      }
    ], 
    "name": "Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells", 
    "pagination": "770-771", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "1bb9015ffa07b89e4be743a762ab1f2aabbd8fc09ad64f646547686df959f378"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "6275274"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "0410462"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/294770a0"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005819260"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/294770a0", 
      "https://app.dimensions.ai/details/publication/pub.1005819260"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:03", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000421.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/294770a0"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/294770a0'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/294770a0'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/294770a0'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/294770a0'


 

This table displays all metadata directly associated to this object as RDF triples.

153 TRIPLES      21 PREDICATES      42 URIs      30 LITERALS      18 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/294770a0 schema:about N23888c0295884e7ea6bbe38d122caa88
2 N460f4b94831c472aac7c84b5cea2f985
3 N8d42630275e64459a6f9851742958529
4 Nafb48bd4b3e84886be415f609f9b10a3
5 Nc1eed1eb5fbd412fae4e3127582df1cb
6 Nc3f87e94af054f87b75eb8860d08f39b
7 Ne0d5fb732f634cba94371cd6fb3b2831
8 Ne79f6502b015452b94961dd3373462a5
9 Nf93e0a95d7864366b66649184d2aea1f
10 anzsrc-for:11
11 anzsrc-for:1112
12 schema:author N95e528b025914a9fb1905105e44ce2bb
13 schema:citation https://app.dimensions.ai/details/publication/pub.1079509088
14 https://app.dimensions.ai/details/publication/pub.1082072821
15 https://doi.org/10.1073/pnas.77.12.7415
16 https://doi.org/10.1073/pnas.77.3.1617
17 schema:datePublished 1981-12
18 schema:datePublishedReg 1981-12-01
19 schema:description A recent nationwide survey of the lymphocyte subpopulations of leukaemia and lymphoma in Japan has disclosed a high incidence of adult T-cell leukaemia (ATL)1. One of the striking features of this disease is the clustering of patients in the southwestern part of Japan1,2. We have established a continuous culture line of leukaemic T cells from a patient with ATL3,4. This cell line, MT-1, was found to carry type C virus particles and ATL-associated antigens (ATLA) which specifically reacted with sera from all ATL patients and about 25% of healthy adults in the endemic area5. We report here that by co-culture of ATL cells from a female patient and normal human cord leukocytes from a male infant, a T-cell line of cord leukocyte origin was established. Numerous type C virus particles as well as ATLA were detected in this cell line.
20 schema:genre research_article
21 schema:inLanguage en
22 schema:isAccessibleForFree false
23 schema:isPartOf N97d8281073ee463d8ff587441a360708
24 Nacc0e1d3af7b4c6e9561b036a26724e6
25 sg:journal.1018957
26 schema:name Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells
27 schema:pagination 770-771
28 schema:productId N30f7980cd2324ce5a7e0131be17a9c05
29 N38c59e593b8c4bf08835c0f9ece28b85
30 N8f160c9f76eb43bb8d41b2edb89ed471
31 N923d8a9bc6644bc5805daa04a1524af7
32 Na35c257626724eb29382129192cc937c
33 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005819260
34 https://doi.org/10.1038/294770a0
35 schema:sdDatePublished 2019-04-11T00:03
36 schema:sdLicense https://scigraph.springernature.com/explorer/license/
37 schema:sdPublisher Na8665b37649c4fc7b0f4c5cca32b97f9
38 schema:url http://www.nature.com/articles/294770a0
39 sgo:license sg:explorer/license/
40 sgo:sdDataset articles
41 rdf:type schema:ScholarlyArticle
42 N23888c0295884e7ea6bbe38d122caa88 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
43 schema:name Leukemia
44 rdf:type schema:DefinedTerm
45 N2bba729086db4f1e9454a2a5ad84c138 rdf:first sg:person.0777010316.75
46 rdf:rest Nceb28c944c784501bf220016e29ed1e5
47 N2f11c45fefbc484e9ba8d04b3c54a311 rdf:first sg:person.0651045615.03
48 rdf:rest Nc8de4e94591e42fb9ad9580f2580c7fa
49 N30f7980cd2324ce5a7e0131be17a9c05 schema:name nlm_unique_id
50 schema:value 0410462
51 rdf:type schema:PropertyValue
52 N38c59e593b8c4bf08835c0f9ece28b85 schema:name pubmed_id
53 schema:value 6275274
54 rdf:type schema:PropertyValue
55 N42d96e3d85e8446395df4ac69ad635d9 rdf:first sg:person.01335063603.32
56 rdf:rest rdf:nil
57 N460f4b94831c472aac7c84b5cea2f985 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
58 schema:name Female
59 rdf:type schema:DefinedTerm
60 N5665247c39684d57b71d2f83c7579741 rdf:first sg:person.01335205436.29
61 rdf:rest N42d96e3d85e8446395df4ac69ad635d9
62 N8d42630275e64459a6f9851742958529 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
63 schema:name Inclusion Bodies, Viral
64 rdf:type schema:DefinedTerm
65 N8f160c9f76eb43bb8d41b2edb89ed471 schema:name readcube_id
66 schema:value 1bb9015ffa07b89e4be743a762ab1f2aabbd8fc09ad64f646547686df959f378
67 rdf:type schema:PropertyValue
68 N923d8a9bc6644bc5805daa04a1524af7 schema:name doi
69 schema:value 10.1038/294770a0
70 rdf:type schema:PropertyValue
71 N95e528b025914a9fb1905105e44ce2bb rdf:first sg:person.01051066610.52
72 rdf:rest Nae9527d3d88248e9b9649a535d8926ab
73 N97d8281073ee463d8ff587441a360708 schema:issueNumber 5843
74 rdf:type schema:PublicationIssue
75 Na35c257626724eb29382129192cc937c schema:name dimensions_id
76 schema:value pub.1005819260
77 rdf:type schema:PropertyValue
78 Na8665b37649c4fc7b0f4c5cca32b97f9 schema:name Springer Nature - SN SciGraph project
79 rdf:type schema:Organization
80 Nacc0e1d3af7b4c6e9561b036a26724e6 schema:volumeNumber 294
81 rdf:type schema:PublicationVolume
82 Nae9527d3d88248e9b9649a535d8926ab rdf:first sg:person.01060701147.16
83 rdf:rest N2f11c45fefbc484e9ba8d04b3c54a311
84 Nafb48bd4b3e84886be415f609f9b10a3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
85 schema:name Middle Aged
86 rdf:type schema:DefinedTerm
87 Nc1eed1eb5fbd412fae4e3127582df1cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
88 schema:name Cell Line
89 rdf:type schema:DefinedTerm
90 Nc3f87e94af054f87b75eb8860d08f39b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name T-Lymphocytes
92 rdf:type schema:DefinedTerm
93 Nc8de4e94591e42fb9ad9580f2580c7fa rdf:first sg:person.010520137352.96
94 rdf:rest N2bba729086db4f1e9454a2a5ad84c138
95 Nceb28c944c784501bf220016e29ed1e5 rdf:first sg:person.01120516555.60
96 rdf:rest N5665247c39684d57b71d2f83c7579741
97 Ne0d5fb732f634cba94371cd6fb3b2831 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
98 schema:name Humans
99 rdf:type schema:DefinedTerm
100 Ne79f6502b015452b94961dd3373462a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
101 schema:name Retroviridae
102 rdf:type schema:DefinedTerm
103 Nf93e0a95d7864366b66649184d2aea1f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Antigens, Neoplasm
105 rdf:type schema:DefinedTerm
106 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
107 schema:name Medical and Health Sciences
108 rdf:type schema:DefinedTerm
109 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
110 schema:name Oncology and Carcinogenesis
111 rdf:type schema:DefinedTerm
112 sg:journal.1018957 schema:issn 0090-0028
113 1476-4687
114 schema:name Nature
115 rdf:type schema:Periodical
116 sg:person.01051066610.52 schema:familyName Miyoshi
117 schema:givenName Isao
118 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01051066610.52
119 rdf:type schema:Person
120 sg:person.010520137352.96 schema:familyName Akagi
121 schema:givenName Tadaatsu
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010520137352.96
123 rdf:type schema:Person
124 sg:person.01060701147.16 schema:familyName Kubonishi
125 schema:givenName Ichiro
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01060701147.16
127 rdf:type schema:Person
128 sg:person.01120516555.60 schema:familyName Shiraishi
129 schema:givenName Yukimasa
130 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01120516555.60
131 rdf:type schema:Person
132 sg:person.01335063603.32 schema:familyName Hinuma
133 schema:givenName Yorio
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335063603.32
135 rdf:type schema:Person
136 sg:person.01335205436.29 schema:familyName Nagata
137 schema:givenName Kinya
138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335205436.29
139 rdf:type schema:Person
140 sg:person.0651045615.03 schema:familyName Yoshimoto
141 schema:givenName Shizuo
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651045615.03
143 rdf:type schema:Person
144 sg:person.0777010316.75 schema:familyName Ohtsuki
145 schema:givenName Yuji
146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0777010316.75
147 rdf:type schema:Person
148 https://app.dimensions.ai/details/publication/pub.1079509088 schema:CreativeWork
149 https://app.dimensions.ai/details/publication/pub.1082072821 schema:CreativeWork
150 https://doi.org/10.1073/pnas.77.12.7415 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048965236
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1073/pnas.77.3.1617 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029171498
153 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...