Antibodies to left-handed Z-DNA bind to interband regions of Drosophila polytene chromosomes View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-12

AUTHORS

Alfred Nordheim, Mary Lou Pardue, Eileen M. Lafer, Achim Möller, B. David Stollar, Alexander Rich

ABSTRACT

Antibodies which are specific to the Z-DNA conformation have been purified and characterized on the basis of their binding to three different DNA polymers which can form this left-handed helix. These antibodies bind specifically to polytene chromosomes of Drosophila melanogaster as visualized by fluorescent staining. The staining is found in the interband regions and its intensity varies among different interbands in a reproducible manner. This is the first identification of the Z-DNA conformation in material of biological origin. More... »

PAGES

417-422

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/294417a0

DOI

http://dx.doi.org/10.1038/294417a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053696957

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6796893


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