Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-11

AUTHORS

Frank Lee, Richard Mulligan, Paul Berg, Gordon Ringold

ABSTRACT

Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome. More... »

PAGES

228

Journal

TITLE

Nature

ISSUE

5838

VOLUME

294

Related Patents

  • Retroviral Vectors Comprising A Functional Splice Donor Site And A Functional Splice Acceptor Site
  • Oncolytic Rhabdovirus
  • Methods And Compositions For Vitamin K Epoxide Reductase
  • Methods And Compositions For Producing Vitamin K Dependent Proteins
  • Process For The Production Of Human Antithrombin Iii (Atiii) And Vectors Suitable Therefor
  • Chimeric Plasmid Vector
  • Remedies For Hepatitis C
  • Methods And Compositions For Vitamin K Epoxide Reductase
  • Methods And Compositions Relating To Improved Lentiviral Vector Production Systems
  • Dna For Eukaryotic Expression Of Cymr
  • Recombinant Dna And Transformant Containing The Same
  • Tissue Preferential Codon Modified Expression Cassettes, Vectors Containing Same, And Uses Thereof
  • Process For The Production Of Human Antithrombin Iii (Atiii) And Vectors Suitable Therefor
  • Methods For Identifying Modulators Of Apoptosis
  • Cumate-Inducible Expression System For Eukaryotic Cells
  • Egln2 Variants And Use Thereof In Preventing Or Treating Thromboembolic Disorders And Coronary Heart Diseases
  • Methods And Compositions Relating To Restricted Expression Lentiviral Vectors And Their Applications
  • Mouse Carrying A Knock-Out Mutation Of The Qpct-Gene
  • Method To Enhance Amplification And Expression Of Foreign Genes
  • Methods And Compositions Relating To Improved Lentiviral Vectors And Their Applications
  • Animal Cell Transformant, Method For Obtaining The Transformant And Method For Producing Desired Foreign Gene Product By Using The Transformant
  • Method To Identify Tumor Suppressor Genes
  • Methods And Compositions Relating To Improved Lentiviral Vectors And Their Applications
  • Fkbp-L And Uses Thereof
  • Egln2 Variants And Use Thereof In Preventing Or Treating Thromboembolic Disorders And Coronary Heart Diseases
  • Immunotherapy And Diagnosis Of Mucormycosis Using Coth
  • Methods And Compositions For The Correlation Of Single Nucleotide Polymorphisms In The Vitamin K Epoxide Reductase Gene And Warfarin Dosage
  • Methods And Compositions For Vitamin K Epoxide Reductase
  • Recombinant Human Thyroid Peroxidase
  • Granulocyte-Binding Antibody Constructs, Their Preparation And Use
  • Retroviral Vectors Comprising A Functional Splice Donor Site And A Functional Splice Acceptor Site
  • Methods And Compositions For Producing Active Vitamin K-Dependent Proteins
  • Methods And Compositions Relating To Improved Lentiviral Vectors And Their Applications
  • Methods And Compositions For Producing Vitamin K Dependent Proteins
  • Methods And Compositions Relating To Improved Lentiviral Vectors And Their Applications
  • Egln2 Variants And Use Thereof In Preventing Or Treating Thromboembolic Disorders And Coronary Heart Disease
  • High Level Inducible Expression Of Heterologous Genes
  • Method Of Producing Foreign Gene Products
  • New Nucleic Acid Sequence, Which Encodes A Polypeptide With Alcohol Dehydrogenase Activity, Comprising E.G. Nucleic Acid Sequence That Hybridizes Under Stringent Conditions With Specific Nucleic Acid Sequence, Useful To Produce Polypeptide
  • Specific Antibodies Against Activated Platelets, The Preparation Thereof And The Use Thereof In Diagnosis And Therapy
  • Control Of Gene Expression By Glucose, Calcium And Temperature
  • Egln2 Variants And Use Thereof In Preventing Or Treating Thromboembolic Disorders And Coronary Heart Diseases
  • Mouse Models Carrying A Knock-Out Mutation Of The Qpctl-Gene
  • Oncolytic Rhabdovirus
  • Methods And Compositions For Vitamin K Epoxide Reductase
  • Isoforms Of The Porcine Liver Esterase
  • Compositions And Methods For Glioblastoma Treatment
  • Methods And Compositions For Producing Vitamin K Dependent Proteins
  • Methods And Compositions Relating To Improved Lentiviral Vector Production Systems
  • Methods For Identifying Modulators Of Apoptosis
  • Methods And Compositions For Vitamin K Epoxide Reductase
  • Methods And Compositions Relating To Restricted Expression Lentiviral Vectors And Their Applications
  • Tetravalent Bispecific Receptors, The Preparation And Use Thereof
  • Method To Identify Tumor Suppressor Genes
  • Method To Enhance Amplification And Expression Of Foreign Genes
  • High Level Inducible Expression Of Heterologous Genes.
  • Methods And Compositions Relating To Improved Lentiviral Vectors And Their Applications
  • Methods And Compositions For Producing Active Vitamin K-Dependent Proteins
  • Fusion Protein Comprising A Furin Derivative Or A Derivative Of A Furin Analogue And A Heterologous Sequence
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/294228a0

    DOI

    http://dx.doi.org/10.1038/294228a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1036697775

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6272123


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Base Sequence", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Transformation, Viral", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cloning, Molecular", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "DNA, Recombinant", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Glucocorticoids", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mammary Tumor Virus, Mouse", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Plasmids", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Tetrahydrofolate Dehydrogenase", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "familyName": "Lee", 
            "givenName": "Frank", 
            "id": "sg:person.0621144735.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621144735.11"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Mulligan", 
            "givenName": "Richard", 
            "id": "sg:person.01261172203.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261172203.49"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Berg", 
            "givenName": "Paul", 
            "id": "sg:person.01007760252.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007760252.94"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Ringold", 
            "givenName": "Gordon", 
            "id": "sg:person.01142776657.04", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142776657.04"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/0092-8674(75)90181-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009148934"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.4.2038", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009608699"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.74.7.2879", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016257195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(81)90129-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017299140"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(79)90333-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017495749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0042-6822(73)90341-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017876073"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.2.665", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021897719"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0042-6822(78)90353-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024616400"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/282579a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024654890", 
              "https://doi.org/10.1038/282579a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-419x(79)90014-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032237969"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-419x(79)90014-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032237969"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(77)90272-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035888199"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/275617a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036271461", 
              "https://doi.org/10.1038/275617a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.ph.38.030176.002233", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037779726"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.71.10.3901", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041730796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.bi.45.070176.003445", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041986157"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.59.2.632", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044673158"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0065-230x(08)60650-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046890961"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.77.7.4216", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050158759"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.4.2072", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051147601"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.1.9.854", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053430959"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.715457", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062644316"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081649942", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1981-11", 
        "datePublishedReg": "1981-11-01", 
        "description": "Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/294228a0", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2508576", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2634963", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2509290", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1018957", 
            "issn": [
              "0090-0028", 
              "1476-4687"
            ], 
            "name": "Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "5838", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "294"
          }
        ], 
        "name": "Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids", 
        "pagination": "228", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "aed090970db2c55c8974a0acd210738d50d75e6790d70357e047774bee3d2914"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "6272123"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "0410462"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/294228a0"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1036697775"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/294228a0", 
          "https://app.dimensions.ai/details/publication/pub.1036697775"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T23:12", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000425.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://www.nature.com/articles/294228a0"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/294228a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/294228a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/294228a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/294228a0'


     

    This table displays all metadata directly associated to this object as RDF triples.

    196 TRIPLES      21 PREDICATES      61 URIs      31 LITERALS      19 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/294228a0 schema:about N01bbb57a24bc405ba8724b9fb8b42070
    2 N264d58f17a99443e94ef19fb47346c8b
    3 N4f958e717a7146b1af7be080426679ab
    4 N5725e7d9ecf549abb7b9a2dd88767be9
    5 N7442a27fb49f40d9913cd8c929fd1f7a
    6 N93ac0d60ce95495c88d20fe8219e0c11
    7 N998455d1fd0f42e2ae0fc29b074ca03d
    8 Nc4ea857f508a472b878c2b50ea3c475f
    9 Nc9bf7087eb13421d9182d649e9efcc2a
    10 Nd00e311b9dba46929828cb86ba5836bb
    11 anzsrc-for:06
    12 anzsrc-for:0604
    13 schema:author N911ed92f64c24af2b4acee452a8d6d96
    14 schema:citation sg:pub.10.1038/275617a0
    15 sg:pub.10.1038/282579a0
    16 https://app.dimensions.ai/details/publication/pub.1081649942
    17 https://doi.org/10.1016/0042-6822(73)90341-3
    18 https://doi.org/10.1016/0042-6822(78)90353-7
    19 https://doi.org/10.1016/0092-8674(75)90181-6
    20 https://doi.org/10.1016/0092-8674(77)90272-0
    21 https://doi.org/10.1016/0092-8674(79)90333-7
    22 https://doi.org/10.1016/0092-8674(81)90129-x
    23 https://doi.org/10.1016/0304-419x(79)90014-3
    24 https://doi.org/10.1016/s0065-230x(08)60650-8
    25 https://doi.org/10.1073/pnas.59.2.632
    26 https://doi.org/10.1073/pnas.71.10.3901
    27 https://doi.org/10.1073/pnas.74.7.2879
    28 https://doi.org/10.1073/pnas.76.2.665
    29 https://doi.org/10.1073/pnas.77.7.4216
    30 https://doi.org/10.1073/pnas.78.4.2038
    31 https://doi.org/10.1073/pnas.78.4.2072
    32 https://doi.org/10.1126/science.715457
    33 https://doi.org/10.1128/mcb.1.9.854
    34 https://doi.org/10.1146/annurev.bi.45.070176.003445
    35 https://doi.org/10.1146/annurev.ph.38.030176.002233
    36 schema:datePublished 1981-11
    37 schema:datePublishedReg 1981-11-01
    38 schema:description Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome.
    39 schema:genre research_article
    40 schema:inLanguage en
    41 schema:isAccessibleForFree false
    42 schema:isPartOf N076d493d912d4871b912d5628b409059
    43 N9e54f7e6a73e4d81a4d83a9600e0b26f
    44 sg:journal.1018957
    45 schema:name Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids
    46 schema:pagination 228
    47 schema:productId N77da51520cb5496d8d66337a8209b25d
    48 N8b8718091e46458cb858328d56c0fd40
    49 N9a8f10a9a1f3461e8559f7c149294843
    50 Nac2ebc07c06c4aaea25676503a78585a
    51 Nbabbfca8237a4b59b673103d710c6e26
    52 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036697775
    53 https://doi.org/10.1038/294228a0
    54 schema:sdDatePublished 2019-04-10T23:12
    55 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    56 schema:sdPublisher N568c7bff2eab4e88bc4b8fd21b4e00a9
    57 schema:url https://www.nature.com/articles/294228a0
    58 sgo:license sg:explorer/license/
    59 sgo:sdDataset articles
    60 rdf:type schema:ScholarlyArticle
    61 N01bbb57a24bc405ba8724b9fb8b42070 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    62 schema:name Mice
    63 rdf:type schema:DefinedTerm
    64 N076d493d912d4871b912d5628b409059 schema:issueNumber 5838
    65 rdf:type schema:PublicationIssue
    66 N264d58f17a99443e94ef19fb47346c8b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    67 schema:name Cell Transformation, Viral
    68 rdf:type schema:DefinedTerm
    69 N41f1a32f18284c769db1f41b8606cbd5 rdf:first sg:person.01261172203.49
    70 rdf:rest Nf144b69bd7de417ab086b887adacccb2
    71 N4f958e717a7146b1af7be080426679ab schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    72 schema:name Mammary Tumor Virus, Mouse
    73 rdf:type schema:DefinedTerm
    74 N568c7bff2eab4e88bc4b8fd21b4e00a9 schema:name Springer Nature - SN SciGraph project
    75 rdf:type schema:Organization
    76 N5725e7d9ecf549abb7b9a2dd88767be9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    77 schema:name Base Sequence
    78 rdf:type schema:DefinedTerm
    79 N7442a27fb49f40d9913cd8c929fd1f7a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    80 schema:name Animals
    81 rdf:type schema:DefinedTerm
    82 N77da51520cb5496d8d66337a8209b25d schema:name nlm_unique_id
    83 schema:value 0410462
    84 rdf:type schema:PropertyValue
    85 N8b8718091e46458cb858328d56c0fd40 schema:name readcube_id
    86 schema:value aed090970db2c55c8974a0acd210738d50d75e6790d70357e047774bee3d2914
    87 rdf:type schema:PropertyValue
    88 N911ed92f64c24af2b4acee452a8d6d96 rdf:first sg:person.0621144735.11
    89 rdf:rest N41f1a32f18284c769db1f41b8606cbd5
    90 N93ac0d60ce95495c88d20fe8219e0c11 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Glucocorticoids
    92 rdf:type schema:DefinedTerm
    93 N998455d1fd0f42e2ae0fc29b074ca03d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    94 schema:name Cloning, Molecular
    95 rdf:type schema:DefinedTerm
    96 N9a8f10a9a1f3461e8559f7c149294843 schema:name doi
    97 schema:value 10.1038/294228a0
    98 rdf:type schema:PropertyValue
    99 N9e54f7e6a73e4d81a4d83a9600e0b26f schema:volumeNumber 294
    100 rdf:type schema:PublicationVolume
    101 Nac2ebc07c06c4aaea25676503a78585a schema:name pubmed_id
    102 schema:value 6272123
    103 rdf:type schema:PropertyValue
    104 Nbabbfca8237a4b59b673103d710c6e26 schema:name dimensions_id
    105 schema:value pub.1036697775
    106 rdf:type schema:PropertyValue
    107 Nc4ea857f508a472b878c2b50ea3c475f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    108 schema:name Plasmids
    109 rdf:type schema:DefinedTerm
    110 Nc9bf7087eb13421d9182d649e9efcc2a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    111 schema:name DNA, Recombinant
    112 rdf:type schema:DefinedTerm
    113 Nd00e311b9dba46929828cb86ba5836bb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    114 schema:name Tetrahydrofolate Dehydrogenase
    115 rdf:type schema:DefinedTerm
    116 Ndc756fe068f344b28cf3814b6b358e6a rdf:first sg:person.01142776657.04
    117 rdf:rest rdf:nil
    118 Nf144b69bd7de417ab086b887adacccb2 rdf:first sg:person.01007760252.94
    119 rdf:rest Ndc756fe068f344b28cf3814b6b358e6a
    120 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    121 schema:name Biological Sciences
    122 rdf:type schema:DefinedTerm
    123 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    124 schema:name Genetics
    125 rdf:type schema:DefinedTerm
    126 sg:grant.2508576 http://pending.schema.org/fundedItem sg:pub.10.1038/294228a0
    127 rdf:type schema:MonetaryGrant
    128 sg:grant.2509290 http://pending.schema.org/fundedItem sg:pub.10.1038/294228a0
    129 rdf:type schema:MonetaryGrant
    130 sg:grant.2634963 http://pending.schema.org/fundedItem sg:pub.10.1038/294228a0
    131 rdf:type schema:MonetaryGrant
    132 sg:journal.1018957 schema:issn 0090-0028
    133 1476-4687
    134 schema:name Nature
    135 rdf:type schema:Periodical
    136 sg:person.01007760252.94 schema:familyName Berg
    137 schema:givenName Paul
    138 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01007760252.94
    139 rdf:type schema:Person
    140 sg:person.01142776657.04 schema:familyName Ringold
    141 schema:givenName Gordon
    142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01142776657.04
    143 rdf:type schema:Person
    144 sg:person.01261172203.49 schema:familyName Mulligan
    145 schema:givenName Richard
    146 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01261172203.49
    147 rdf:type schema:Person
    148 sg:person.0621144735.11 schema:familyName Lee
    149 schema:givenName Frank
    150 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0621144735.11
    151 rdf:type schema:Person
    152 sg:pub.10.1038/275617a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036271461
    153 https://doi.org/10.1038/275617a0
    154 rdf:type schema:CreativeWork
    155 sg:pub.10.1038/282579a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024654890
    156 https://doi.org/10.1038/282579a0
    157 rdf:type schema:CreativeWork
    158 https://app.dimensions.ai/details/publication/pub.1081649942 schema:CreativeWork
    159 https://doi.org/10.1016/0042-6822(73)90341-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017876073
    160 rdf:type schema:CreativeWork
    161 https://doi.org/10.1016/0042-6822(78)90353-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024616400
    162 rdf:type schema:CreativeWork
    163 https://doi.org/10.1016/0092-8674(75)90181-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009148934
    164 rdf:type schema:CreativeWork
    165 https://doi.org/10.1016/0092-8674(77)90272-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035888199
    166 rdf:type schema:CreativeWork
    167 https://doi.org/10.1016/0092-8674(79)90333-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017495749
    168 rdf:type schema:CreativeWork
    169 https://doi.org/10.1016/0092-8674(81)90129-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017299140
    170 rdf:type schema:CreativeWork
    171 https://doi.org/10.1016/0304-419x(79)90014-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032237969
    172 rdf:type schema:CreativeWork
    173 https://doi.org/10.1016/s0065-230x(08)60650-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046890961
    174 rdf:type schema:CreativeWork
    175 https://doi.org/10.1073/pnas.59.2.632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044673158
    176 rdf:type schema:CreativeWork
    177 https://doi.org/10.1073/pnas.71.10.3901 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041730796
    178 rdf:type schema:CreativeWork
    179 https://doi.org/10.1073/pnas.74.7.2879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016257195
    180 rdf:type schema:CreativeWork
    181 https://doi.org/10.1073/pnas.76.2.665 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021897719
    182 rdf:type schema:CreativeWork
    183 https://doi.org/10.1073/pnas.77.7.4216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050158759
    184 rdf:type schema:CreativeWork
    185 https://doi.org/10.1073/pnas.78.4.2038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009608699
    186 rdf:type schema:CreativeWork
    187 https://doi.org/10.1073/pnas.78.4.2072 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051147601
    188 rdf:type schema:CreativeWork
    189 https://doi.org/10.1126/science.715457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062644316
    190 rdf:type schema:CreativeWork
    191 https://doi.org/10.1128/mcb.1.9.854 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053430959
    192 rdf:type schema:CreativeWork
    193 https://doi.org/10.1146/annurev.bi.45.070176.003445 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041986157
    194 rdf:type schema:CreativeWork
    195 https://doi.org/10.1146/annurev.ph.38.030176.002233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037779726
    196 rdf:type schema:CreativeWork
     




    Preview window. Press ESC to close (or click here)


    ...