Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-11

AUTHORS

Frank Lee, Richard Mulligan, Paul Berg, Gordon Ringold

ABSTRACT

Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome. More... »

PAGES

228-232

Journal

TITLE

Nature

ISSUE

5838

VOLUME

294

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/294228a0

    DOI

    http://dx.doi.org/10.1038/294228a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1036697775

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6272123


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    171 schema:name Center for Cancer Research, Massachusetts Institute of Technology, 02139, Cambridge, Massachusetts, USA
    172 Department of Biochemistry, Stanford University School of Medicine, 94305, Stanford, California, USA
    173 Department of Pharmacology, Stanford University School of Medicine, 94305, Stanford, California, USA
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