Cell-surface expression of influenza haemagglutinin from a cloned DNA copy of the RNA gene View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-10

AUTHORS

Mary-Jane Gething, Joe Sambrook

ABSTRACT

By replacing either the eight early or the late genes of SV40 with a cloned copy of the influenza virus haemagglutinin gene we have constructed recombinant viruses which, in infected cells, express large quantities of haemagglutinin. This glycoprotein, over 10(8) molecules of which are produced per cell, is identical in molecular weight to authentic influenza virus haemagglutinin, accumulates at the cell surface and displays haemabsorbing activity. More... »

PAGES

620-625

References to SciGraph publications

  • 1981-01. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution in NATURE
  • 1981-03. Structure of the neuraminidase gene in human influenza virus A/PR/8/34 in NATURE
  • 1981-07. Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype in NATURE
  • 1978-05. Complete nucleotide sequence of SV40 DNA in NATURE
  • 1980-09. Cloning and DNA sequence of double-stranded copies of haemagglutinin genes from H2 and H3 strains elucidates antigenic shift and drift in human influenza virus in NATURE
  • 1980-01. Influenza antigenic determinants are expressed from haemagglutinin genes cloned in Escherichia coli in NATURE
  • 1980-01. The mechanism of protein secretion across membranes in NATURE
  • 1981-05. Primary structure of a murine transplantation antigen in NATURE
  • 1980-08. Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75 in NATURE
  • 1980-11. Nucleotide sequence of cDNA coding for Semliki Forest virus membrane glycoproteins in NATURE
  • 1976-10. Synthetic lacoperator DNA is functional in vivo in NATURE
  • 1979-09. Expression of the chromosomal mouse βmaj-globin gene cloned in SV40 in NATURE
  • 1981-01. Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation in NATURE
  • 1980-10. The structure of one of the eight or more distinct chromosomal genes for human interferon-α in NATURE
  • 1979-01. Synthesis of rabbit β-globin in cultured monkey kidney cells following infection with a SV40 β-globin recombinant genome in NATURE
  • 1979-11. Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA in NATURE
  • Journal

    TITLE

    Nature

    ISSUE

    5834

    VOLUME

    293

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/293620a0

    DOI

    http://dx.doi.org/10.1038/293620a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1049262366

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/6270568


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    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/293620a0'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/293620a0'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/293620a0'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/293620a0'


     

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