Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-10

AUTHORS

Nancy A. Jenkins, Neal G. Copeland, Benjamin A. Taylor, Barbara K. Lee

ABSTRACT

The single endogenous DBA/2J ectropic provirus segregated concordantly with the dilute (d) coat colour mutation on chromosome 9 in 53/53 DBA/2J-derived recombinant inbred mouse strains and all seven inbred and mutant strains tested that carry the d allele. Analysis of DNA from a spontaneous DBA/2J d revertant (d+2J) showed that these mice lack ecotropic-specific MuLV DNA sequences and suggested that the dilute mutation resulted from integration of an ecotropic provirus into the mouse genome. More... »

PAGES

370-374

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/293370a0

DOI

http://dx.doi.org/10.1038/293370a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008897930

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/6268990


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