Sequence and organization of the human mitochondrial genome View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1981-04

AUTHORS

S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger, P H Schreier, A J Smith, R Staden, I G Young

ABSTRACT

The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22 tRNAs, cytochrome c oxidase subunits I, II and III, ATPase subunit 6, cytochrome b and eight other predicted protein coding genes have been located. The sequence shows extreme economy in that the genes have none or only a few noncoding bases between them, and in many cases the termination codons are not coded in the DNA but are created post-transcriptionally by polyadenylation of the mRNAs. More... »

PAGES

457-465

Journal

TITLE

Nature

ISSUE

5806

VOLUME

290

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/290457a0

    DOI

    http://dx.doi.org/10.1038/290457a0

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1038487698

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/7219534


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